diff --git a/include/vkd3d.h b/include/vkd3d.h
index 175a278c3f..3bf7b5626b 100644
--- a/include/vkd3d.h
+++ b/include/vkd3d.h
@@ -111,6 +111,7 @@ extern "C" {
 #define VKD3D_CONFIG_FLAG_INSTRUCTION_QA_CHECKS (1ull << 53)
 #define VKD3D_CONFIG_FLAG_TRANSFER_QUEUE (1ull << 54)
 #define VKD3D_CONFIG_FLAG_NO_GPU_UPLOAD_HEAP (1ull << 55)
+#define VKD3D_CONFIG_FLAG_ONE_TIME_SUBMIT (1ull << 56)
 
 struct vkd3d_instance;
 
diff --git a/libs/vkd3d/command.c b/libs/vkd3d/command.c
index a1d284b25a..e1e4dea6af 100644
--- a/libs/vkd3d/command.c
+++ b/libs/vkd3d/command.c
@@ -1906,7 +1906,8 @@ static HRESULT d3d12_command_list_begin_command_buffer(struct d3d12_command_list
 
     begin_info.sType = VK_STRUCTURE_TYPE_COMMAND_BUFFER_BEGIN_INFO;
     begin_info.pNext = NULL;
-    begin_info.flags = 0;
+    begin_info.flags = (vkd3d_config_flags & VKD3D_CONFIG_FLAG_ONE_TIME_SUBMIT) ?
+            VK_COMMAND_BUFFER_USAGE_ONE_TIME_SUBMIT_BIT : 0;
     begin_info.pInheritanceInfo = NULL;
 
     if ((vr = VK_CALL(vkBeginCommandBuffer(list->cmd.vk_command_buffer, &begin_info))) < 0)
@@ -2018,7 +2019,8 @@ static void d3d12_command_list_begin_new_sequence(struct d3d12_command_list *lis
 
     begin_info.sType = VK_STRUCTURE_TYPE_COMMAND_BUFFER_BEGIN_INFO;
     begin_info.pNext = NULL;
-    begin_info.flags = 0;
+    begin_info.flags = (vkd3d_config_flags & VKD3D_CONFIG_FLAG_ONE_TIME_SUBMIT) ?
+            VK_COMMAND_BUFFER_USAGE_ONE_TIME_SUBMIT_BIT : 0;
     begin_info.pInheritanceInfo = NULL;
     if ((vr = VK_CALL(vkBeginCommandBuffer(iteration->vk_command_buffer, &begin_info))) < 0)
     {
@@ -2112,7 +2114,8 @@ static HRESULT d3d12_command_allocator_allocate_init_command_buffer(struct d3d12
 
     begin_info.sType = VK_STRUCTURE_TYPE_COMMAND_BUFFER_BEGIN_INFO;
     begin_info.pNext = NULL;
-    begin_info.flags = 0;
+    begin_info.flags = (vkd3d_config_flags & VKD3D_CONFIG_FLAG_ONE_TIME_SUBMIT) ?
+            VK_COMMAND_BUFFER_USAGE_ONE_TIME_SUBMIT_BIT : 0;
     begin_info.pInheritanceInfo = NULL;
 
     if ((vr = VK_CALL(vkBeginCommandBuffer(list->cmd.iterations[0].vk_init_commands, &begin_info))) < 0)
@@ -2162,7 +2165,8 @@ static HRESULT d3d12_command_allocator_allocate_init_post_indirect_command_buffe
 
     begin_info.sType = VK_STRUCTURE_TYPE_COMMAND_BUFFER_BEGIN_INFO;
     begin_info.pNext = NULL;
-    begin_info.flags = 0;
+    begin_info.flags = (vkd3d_config_flags & VKD3D_CONFIG_FLAG_ONE_TIME_SUBMIT) ?
+            VK_COMMAND_BUFFER_USAGE_ONE_TIME_SUBMIT_BIT : 0;
     begin_info.pInheritanceInfo = NULL;
 
     if ((vr = VK_CALL(vkBeginCommandBuffer(iteration->vk_init_commands, &begin_info))) < 0)
diff --git a/libs/vkd3d/device.c b/libs/vkd3d/device.c
index 9a6ee1fb98..b2d2b2e804 100644
--- a/libs/vkd3d/device.c
+++ b/libs/vkd3d/device.c
@@ -982,6 +982,7 @@ static const struct vkd3d_debug_option vkd3d_config_options[] =
     {"instruction_qa_checks", VKD3D_CONFIG_FLAG_INSTRUCTION_QA_CHECKS},
     {"transfer_queue", VKD3D_CONFIG_FLAG_TRANSFER_QUEUE},
     {"no_gpu_upload_heap", VKD3D_CONFIG_FLAG_NO_GPU_UPLOAD_HEAP},
+    {"one_time_submit", VKD3D_CONFIG_FLAG_ONE_TIME_SUBMIT},
 };
 
 static void vkd3d_config_flags_init_once(void)