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DESCRIPTION
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Package: SIMPLEs
Type: Package
Title: SIMPLEs: single-cell RNA sequencing imputation and cell clustering methods by modeling gene module variation
Version: 0.1.0
Author: Zhirui,Hu, Songpeng Zu
Maintainer: Zhirui Hu <[email protected]>
Description: SIMPLE is a R package that imputes "dropout" values (i.e. zero or small entries)
in the single cell RNASeq data based on cell similarities and gene correlations.
The imputed matrix can be used for dimension reduction and visualization of the
cell spectrum, to identify markers between different samples and construct gene
co-expression network.
License: MIT
Encoding: UTF-8
Depends: R (>= 3.5.0)
Imports:
MASS (>= 7.3-51.4),
glmnet (>= 2.0-16),
matrixStats (>= 0.54.0),
mixtools (>= 1.1.0),
Rsolnp (>= 1.16),
msm (>= 1.6.7),
doParallel (>= 1.0.15),
foreach (>= 1.4.7),
irlba (>= 2.3.3)
RoxygenNote: 7.1.1
Suggests:
knitr,
rmarkdown,
Rtsne,
mclust,
ggplot2
VignetteBuilder: knitr
LazyData: true