diff --git a/modifiers/caliper-cuda/configs/modifier.yaml b/modifiers/caliper-cuda/configs/modifier.yaml
new file mode 100644
index 000000000..7b5434837
--- /dev/null
+++ b/modifiers/caliper-cuda/configs/modifier.yaml
@@ -0,0 +1,18 @@
+# Copyright 2023 Lawrence Livermore National Security, LLC and other
+# Benchpark Project Developers. See the top-level COPYRIGHT file for details.
+#
+# SPDX-License-Identifier: Apache-2.0
+
+variables:
+  modifier_package_name: 'caliper-cuda'
+  modifier_spack_variant: '+caliper'
+
+modifiers:
+  - name: caliper-cuda
+    mode: cuda
+
+spack:
+  packages:
+    caliper-cuda:
+      spack_spec: caliper+adiak+mpi~libunwind~libdw~papi+cuda cuda_arch=={cuda_arch}
+
diff --git a/modifiers/caliper-cuda/modifier.py b/modifiers/caliper-cuda/modifier.py
new file mode 100644
index 000000000..7761a467e
--- /dev/null
+++ b/modifiers/caliper-cuda/modifier.py
@@ -0,0 +1,27 @@
+# Copyright 2023 Lawrence Livermore National Security, LLC and other
+# Benchpark Project Developers. See the top-level COPYRIGHT file for details.
+#
+# SPDX-License-Identifier: Apache-2.0
+
+from ramble.modkit import *
+from ramble.mod.benchpark.caliper import Caliper as CaliperBase
+
+
+class CaliperCuda(CaliperBase):
+    """Define a modifier for Caliper"""
+
+    name = "caliper-cuda"
+
+    mode(
+        "cuda",
+        description="Profile CUDA API functions",
+    )
+
+    _cali_datafile = CaliperBase._cali_datafile
+
+    env_var_modification(
+        "CALI_CONFIG",
+        "spot(output={}, profile.cuda)".format(_cali_datafile),
+        method="set",
+        modes=["cuda"],
+    )