diff --git a/packages/p/python-bloscpack/.files b/packages/p/python-bloscpack/.files
index e201b67e09e..d42fb4f2139 100644
Binary files a/packages/p/python-bloscpack/.files and b/packages/p/python-bloscpack/.files differ
diff --git a/packages/p/python-bloscpack/.rev b/packages/p/python-bloscpack/.rev
index dc5c7e39e56..1522634b91c 100644
--- a/packages/p/python-bloscpack/.rev
+++ b/packages/p/python-bloscpack/.rev
@@ -56,4 +56,15 @@
     <comment></comment>
     <requestid>946886</requestid>
   </revision>
+  <revision rev="8" vrev="7">
+    <srcmd5>414007d86f5d26983958a47bb9829a0d</srcmd5>
+    <version>0.16.0</version>
+    <time>1667499292</time>
+    <user>dimstar_suse</user>
+    <comment>- Add drop-python2-support.patch to remove python-six
+  gh#Blosc/bloscpack#118
+- Remove python_module definition
+</comment>
+    <requestid>1033055</requestid>
+  </revision>
 </revisionlist>
diff --git a/packages/p/python-bloscpack/drop-python2-support.patch b/packages/p/python-bloscpack/drop-python2-support.patch
new file mode 100644
index 00000000000..37d9891f8f4
--- /dev/null
+++ b/packages/p/python-bloscpack/drop-python2-support.patch
@@ -0,0 +1,212 @@
+Index: bloscpack-0.16.0/bloscpack/args.py
+===================================================================
+--- bloscpack-0.16.0.orig/bloscpack/args.py
++++ bloscpack-0.16.0/bloscpack/args.py
+@@ -3,7 +3,6 @@
+ 
+ 
+ import blosc
+-from six import integer_types, string_types
+ 
+ 
+ from .abstract_objects import (MutableMappingObject,
+@@ -181,7 +180,7 @@ def calculate_nchunks(in_file_size, chun
+         return (1, 0, 0)
+         log.verbose("Input was length zero, ignoring 'chunk_size'")
+     # convert a human readable description to an int
+-    if isinstance(chunk_size, string_types):
++    if isinstance(chunk_size, str):
+         chunk_size = reverse_pretty(chunk_size)
+     check_range('chunk_size', chunk_size, 1, blosc.BLOSC_MAX_BUFFERSIZE)
+     # downcast
+@@ -264,7 +263,7 @@ def _handle_max_apps(offsets, nchunks, m
+             # it's a callable all right
+             log.debug("max_app_chunks is a callable")
+             max_app_chunks = max_app_chunks(nchunks)
+-            if not isinstance(max_app_chunks, integer_types):
++            if not isinstance(max_app_chunks, int):
+                 raise ValueError(
+                         "max_app_chunks callable returned a non integer "
+                         "of type '%s'" % type(max_app_chunks))
+@@ -272,7 +271,7 @@ def _handle_max_apps(offsets, nchunks, m
+             if max_app_chunks < 0:
+                 raise ValueError(
+                         'max_app_chunks callable returned a negative integer')
+-        elif isinstance(max_app_chunks, integer_types):
++        elif isinstance(max_app_chunks, int):
+             # it's a plain int, check its range
+             log.debug("max_app_chunks is an int")
+             check_range('max_app_chunks', max_app_chunks, 0, MAX_CHUNKS)
+@@ -425,7 +424,7 @@ class MetadataArgs(MutableMappingObject)
+     def effective_max_meta_size(self, meta_size):
+         if hasattr(self.max_meta_size, '__call__'):
+             max_meta_size = self.max_meta_size(meta_size)
+-        elif isinstance(self.max_meta_size, integer_types):
++        elif isinstance(self.max_meta_size, int):
+             max_meta_size = self.max_meta_size
+         log.debug('max meta size is deemed to be: %d' % max_meta_size)
+         return max_meta_size
+Index: bloscpack-0.16.0/bloscpack/file_io.py
+===================================================================
+--- bloscpack-0.16.0.orig/bloscpack/file_io.py
++++ bloscpack-0.16.0/bloscpack/file_io.py
+@@ -8,8 +8,6 @@ import itertools
+ import os.path as path
+ 
+ import blosc
+-import six
+-from six.moves import xrange
+ from deprecated import deprecated
+ 
+ 
+@@ -86,7 +84,7 @@ def _write_metadata(output_fp, metadata,
+     serializer_impl = SERIALIZERS_LOOKUP[metadata_args.magic_format]
+     metadata = serializer_impl.dumps(metadata)
+     meta_size = len(metadata)
+-    if six.PY3 and isinstance(metadata, str):
++    if isinstance(metadata, str):
+         metadata = metadata.encode()
+     if metadata_args.should_compress:
+         codec_impl = metadata_args.meta_codec_impl
+@@ -128,7 +126,7 @@ def _write_metadata(output_fp, metadata,
+     output_fp.write(raw_metadata_header)
+     output_fp.write(metadata)
+     prealloc = max_meta_size - meta_comp_size
+-    for i in xrange(prealloc):
++    for i in range(prealloc):
+         output_fp.write(b'\x00')
+     metadata_total += prealloc
+     log.debug("metadata has %d preallocated empty bytes" % prealloc)
+@@ -227,7 +225,7 @@ def _read_metadata(input_fp):
+             ('compressed' if metadata_header.meta_codec != 'None' else
+                 'uncompressed', metadata_header.meta_comp_size))
+     serializer_impl = SERIALIZERS_LOOKUP[metadata_header.magic_format]
+-    if six.PY3 and isinstance(metadata, bytes):
++    if isinstance(metadata, bytes):
+         metadata = metadata.decode()
+     metadata = serializer_impl.loads(metadata)
+     return metadata, metadata_header
+@@ -257,7 +255,7 @@ def _read_offsets(input_fp, bloscpack_he
+         offsets_raw = input_fp.read(8 * total_entries)
+         log.debug('Read raw offsets: %s' % repr(offsets_raw))
+         offsets = [decode_int64(offsets_raw[j - 8:j]) for j in
+-                   xrange(8, bloscpack_header.nchunks * 8 + 1, 8)]
++                   range(8, bloscpack_header.nchunks * 8 + 1, 8)]
+         log.debug('Offsets: %s' % offsets)
+         return offsets
+     else:
+@@ -363,7 +361,7 @@ class CompressedFPSource(CompressedSourc
+         self.nchunks = self.bloscpack_header.nchunks
+ 
+     def __iter__(self):
+-        for i in xrange(self.nchunks):
++        for i in range(self.nchunks):
+             compressed, header, digest = _read_compressed_chunk_fp(self.input_fp, self.checksum_impl)
+             compressed(digest)
+ 
+Index: bloscpack-0.16.0/bloscpack/headers.py
+===================================================================
+--- bloscpack-0.16.0.orig/bloscpack/headers.py
++++ bloscpack-0.16.0/bloscpack/headers.py
+@@ -11,7 +11,6 @@ except ImportError:
+ 
+ 
+ import blosc
+-from six import PY3, integer_types, binary_type
+ 
+ from .abstract_objects import (MutableMappingObject,
+                                )
+@@ -40,7 +39,7 @@ from . import log
+ 
+ def check_range(name, value, min_, max_):
+     """ Check that a variable is in range. """
+-    if not isinstance(value, integer_types):
++    if not isinstance(value, int):
+         raise TypeError("'%s' must be of type 'int'" % name)
+     elif not min_ <= value <= max_:
+         raise ValueError(
+@@ -49,7 +48,7 @@ def check_range(name, value, min_, max_)
+ 
+ 
+ def _check_str(name, value, max_len):
+-    if not isinstance(value, binary_type):
++    if not isinstance(value, bytes):
+         raise TypeError("'%s' must be of type 'str'/'bytes'" % name)
+     elif len(value) > max_len:
+         raise ValueError("'%s' can be of max length '%i' but is: '%s'" %
+@@ -103,10 +102,7 @@ def check_options_zero(options, indices)
+ 
+ 
+ def decode_uint8(byte):
+-    if PY3:
+-        return byte
+-    else:
+-        return struct.unpack('<B', byte)[0]
++    return byte
+ 
+ 
+ def decode_uint32(fourbyte):
+@@ -126,10 +122,7 @@ def decode_bitfield(byte):
+ 
+ 
+ def decode_magic_string(str_):
+-    if PY3:
+-        return str_.strip(b'\x00')
+-    else:
+-        return str_.strip('\x00')
++    return str_.strip(b'\x00')
+ 
+ 
+ def encode_uint8(byte):
+Index: bloscpack-0.16.0/bloscpack/memory_io.py
+===================================================================
+--- bloscpack-0.16.0.orig/bloscpack/memory_io.py
++++ bloscpack-0.16.0/bloscpack/memory_io.py
+@@ -2,7 +2,6 @@
+ # vim :set ft=py:
+ 
+ import blosc
+-from six.moves import xrange
+ 
+ from .abstract_io import (PlainSource,
+                           CompressedSource,
+@@ -38,7 +37,7 @@ class CompressedMemorySource(CompressedS
+             self.checksums = compressed_memory_sink.checksums
+ 
+     def __iter__(self):
+-        for i in xrange(self.nchunks):
++        for i in range(self.nchunks):
+             compressed = self.chunks[i]
+             digest = self.checksums[i] if self.checksum else None
+             compressed(digest)
+Index: bloscpack-0.16.0/bloscpack/numpy_io.py
+===================================================================
+--- bloscpack-0.16.0.orig/bloscpack/numpy_io.py
++++ bloscpack-0.16.0/bloscpack/numpy_io.py
+@@ -6,8 +6,6 @@ import ast
+ 
+ import blosc
+ import numpy
+-import six
+-from six.moves import xrange
+ from deprecated import deprecated
+ 
+ 
+@@ -88,7 +86,7 @@ class PlainNumpySource(PlainSource):
+                 )
+         self.nitems = int(self.chunk_size / self.ndarray.itemsize)
+         offset = self.ptr
+-        for i in xrange(self.nchunks - 1):
++        for i in range(self.nchunks - 1):
+             offset(self.nitems)
+             offset += self.chunk_size
+         offset(int(self.last_chunk / self.ndarray.itemsize))
+@@ -111,8 +109,6 @@ def _conv(descr):
+             descr = [_conv(d) for d in descr]
+         else:
+             descr = tuple([_conv(d) for d in descr])
+-    elif six.PY2 and isinstance(descr, unicode):  # pragma: no cover
+-        descr = str(descr)
+     return descr
+ 
+ 
diff --git a/packages/p/python-bloscpack/python-bloscpack.changes b/packages/p/python-bloscpack/python-bloscpack.changes
index 3904ba15928..9c7c1d2f71f 100644
--- a/packages/p/python-bloscpack/python-bloscpack.changes
+++ b/packages/p/python-bloscpack/python-bloscpack.changes
@@ -1,3 +1,10 @@
+-------------------------------------------------------------------
+Thu Nov  3 11:41:40 UTC 2022 - Daniel Garcia <daniel.garcia@suse.com>
+
+- Add drop-python2-support.patch to remove python-six
+  gh#Blosc/bloscpack#118
+- Remove python_module definition
+
 -------------------------------------------------------------------
 Sun Jan 16 16:12:38 UTC 2022 - Benjamin Greiner <code@bnavigator.de>
 
diff --git a/packages/p/python-bloscpack/python-bloscpack.spec b/packages/p/python-bloscpack/python-bloscpack.spec
index fe3325bcf07..aa7dc2be746 100644
--- a/packages/p/python-bloscpack/python-bloscpack.spec
+++ b/packages/p/python-bloscpack/python-bloscpack.spec
@@ -1,7 +1,7 @@
 #
 # spec file for package python-bloscpack
 #
-# Copyright (c) 2021 SUSE LLC
+# Copyright (c) 2022 SUSE LLC
 #
 # All modifications and additions to the file contributed by third parties
 # remain the property of their copyright owners, unless otherwise agreed
@@ -16,8 +16,6 @@
 #
 
 
-%{?!python_module:%define python_module() python3-%{**}}
-%define skip_python2 1
 Name:           python-bloscpack
 Version:        0.16.0
 Release:        0
@@ -28,12 +26,13 @@ Source:         https://files.pythonhosted.org/packages/source/b/bloscpack/blosc
 # PATCH-FEATURE-UPSTREAM remove_nose.patch gh#Blosc/bloscpack#99 mcepl@suse.com
 # Remove nose dependency
 Patch0:         remove_nose.patch
+# PATCH-FIX-UPSTREAM drop-python2-support.patch gh#Blosc/bloscpack#118
+Patch1:         drop-python2-support.patch
 BuildRequires:  %{python_module setuptools}
 BuildRequires:  fdupes
 BuildRequires:  python-rpm-macros
 Requires:       python-blosc
 Requires:       python-numpy
-Requires:       python-six
 Requires(post): update-alternatives
 Requires(postun):update-alternatives
 Recommends:     cryptography >= 1.3.4
@@ -46,7 +45,6 @@ BuildRequires:  %{python_module cryptography >= 1.3.4}
 BuildRequires:  %{python_module numpy}
 BuildRequires:  %{python_module pyOpenSSL >= 0.14}
 BuildRequires:  %{python_module pytest}
-BuildRequires:  %{python_module six}
 # /SECTION
 %python_subpackages