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Hybrid topologies for nucleic acids #6

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zharmad opened this issue Jan 9, 2017 · 0 comments
Open

Hybrid topologies for nucleic acids #6

zharmad opened this issue Jan 9, 2017 · 0 comments

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@zharmad
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zharmad commented Jan 9, 2017

Hi, a project of mine involves single-stranded RNA/protein interactions, where we have some experimental / structural information on affinity changes based on single site mutations of the RNA sequence. I'm considering mutational free energy calculations as a complement to help prove our structural models.
I've noted in the code here that while there is no current support in mutate_v2.py to create hybrid topology files, there seems to be an intention of adding the relevant files (via adding mutres_dna.mtp, etc.)

Are there people who do intend to work on this that you know of? Or is this a paused feature?

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