From a2c990fca47976f6cc0e886af9e646974864872e Mon Sep 17 00:00:00 2001 From: Lieke Schoenmaker Date: Mon, 1 Apr 2019 12:16:16 +0200 Subject: [PATCH] update treatment mapping --- .../src/main/resources/treatment_mapping.csv | 57 +++++++++---------- 1 file changed, 26 insertions(+), 31 deletions(-) diff --git a/patient-db/src/main/resources/treatment_mapping.csv b/patient-db/src/main/resources/treatment_mapping.csv index 811f2e478d..fc4af2c62c 100644 --- a/patient-db/src/main/resources/treatment_mapping.csv +++ b/patient-db/src/main/resources/treatment_mapping.csv @@ -11,15 +11,16 @@ drug,type,mechanism,synonyms "Afatinib",Targeted therapy,"Anti-EGFR","" "Alectinib",Targeted therapy,"ALK inhitor","" "Alendronic acid",Bisphosphonates,"Bisphosphonates","" +"Alpelisib",Experimental therapy,"PI3K inhibitor","" "AMG 211",Experimental therapy,"Experimental","" "AMG 232",Experimental therapy,"Experimental","" -"Anastrozole",Hormonal therapy,"Aromatase inhibitor","anastozol,Arimidex,anastorozole, Anastrazol" +"Anastrozole",Hormonal therapy,"Aromatase inhibitor","anastozol,Arimidex,anastorozole, Anastrazol, anatrozol" "Androgen deprivation therapy (ADT)",Androgen/estrogen deprivation therapy,"GnRH (ant)agonist","androgen deprivation therapy, ADT, intermittent ADT" "Anthracycline",Chemotherapy,"Anthracycline","" "Anti - Glucocorticoid induced TNF receptor (GITR)",Experimental therapy,"Anti-GITR","Anti-GITR" -"Antiandrogen",Androgen/estrogen deprivation therapy,"GnRH (ant)agonist","Anti-androgen" "anti-PD-1 (PDR001)",Immunotherapy,"Anti-PD-1","PDR001, Anti-PD1" "anti-PD-1 (PDR001) or placebo",Randomized trial,"Anti-PD-1 or Placebo","PDR001 or placebo" +"Antiandrogen",Androgen/estrogen deprivation therapy,"GnRH (ant)agonist","Anti-androgen" "Apalutamide",Hormonal therapy,"Anti-AR","" "Aromatase inhibitor (AI)",Hormonal therapy,"Aromatase inhibitor","unknown aromatase inhibitor" "Atezolizumab",Immunotherapy,"Anti-PD-L1","atezolumab" @@ -72,8 +73,7 @@ drug,type,mechanism,synonyms "Cyclophosphamide, Methotrexate, Fluorouracil (CMF)",Chemotherapy,"Alkylating, antifolate, pyrimidine (ant)agonist","CMF" "Cyclophosphamide, Vincristine Sulfate, Procarbazine Hydrochloride, Prednisone (COPP)",Chemotherapy,"Alkylating, vinca alkaloid, alkylating, glucocorticoid","COPP" "Cyproterone",Androgen/estrogen deprivation therapy,"Anti androgen","Androcur" -"Cytarabine",Chemotherapy,"Pyrimidine (ant)agonist","cyturabine,depocyt" -"Cytarabin",Chemotherapy,"Antimetabolite","cytaribine" +"Cytarabin",Chemotherapy,"Pyrimidine (ant)agonist","cytaribine, cyturabine,depocyt" "Dabrafenib",Targeted therapy,"BRAF inhibitor","" "Dacarbazine",Chemotherapy,"Alkylating","" "Dactinomycin",Chemotherapy,"Antitumor antibiotic","Dactinomycine" @@ -81,9 +81,7 @@ drug,type,mechanism,synonyms "Darolutamide",Experimental therapy,"Experimental","ODM-201" "Degarelix",Androgen/estrogen deprivation therapy,"GnRH (ant)agonist","Firmagon" "Dendritic cell therapy (DCVAC)",Experimental therapy,"Immune therapy","DC therapy,DCVAC/PCa,Dendritic cell,dendritic cell vaccination,dendritic cell vacination,dendritic cell vacine,DC vaccinations,Dendritic cell therapy,myeloid and plasmacytoid DC vaccinations, DC immunotherapy (DENIM-study)" -"Dendritic cell vaccination (DCVAC) or placebo",Randomized trial,"Immune therapy or placebo","DCVAC/PCa of placebo, DCVAC/placebo, MIND-DC trial" -"Dendritic cells or placebo",Randomized trial,"Immune therapy or placebo","Dendritic cells or placebo (study)" -"Dendtritic cell activation or placebo",Randomized trial,"Immune therapy or placebo","dendtritic celactivation or placebo" +"Dendritic cell therapy (DCVAC) or placebo",Randomized trial,"Immune therapy or placebo","DCVAC/PCa of placebo, DCVAC/placebo, MIND-DC trial, Dendritic cells or placebo (study), dendtritic celactivation or placebo" "Denosumab",Boneregulating agent,"Anti-RANK-L","" "Dexamethasone",Other,"Glucocorticoid","Dexamethason" "Dexamethasone (liposomal)",Other,"Glucocorticoid","liposomaal dexamethason" @@ -93,7 +91,7 @@ drug,type,mechanism,synonyms "Docetaxel",Chemotherapy,"Taxane","dcoetaxel,Docetaxel.,Doxatel,Taxotere, Doxacetel" "Docetaxel (CriPec)",Chemotherapy,"Taxane","CriPec Docetaxel, Cri-Pec Docetaxel (Napoly study)" "Docetaxel, Doxorubicin, Cyclophosphamide (TAC)",Chemotherapy,"Taxane, anthracycline, alkylating","TAC, TCA" -"Doxorubicin",Chemotherapy,"Anthracycline","Doxorubicine (Adriamycine),Doxurubicine,Adriamycine,hydrodoxorubicin,Adriamyne,Adryamicine,doxoburicine,Doxorubine,Myocet,Adriamycin,adriacimicyne,dxorubicine,Doxorubicine, doxorubicine (mamma), Dox" +"Doxorubicin",Chemotherapy,"Anthracycline","Doxorubicine (Adriamycine),Doxurubicine,Adriamycine,hydrodoxorubicin,Adriamyne,Adryamicine,doxoburicine,Doxorubine,Myocet,Adriamycin,adriacimicyne,Doxorubicine, doxorubicine (mamma), Dox" "Doxorubicin (liposomal)",Chemotherapy,"Anthracycline","PLD,caelyx,Lipodoxorubicin, Caelyx (Doxorubicine in pegylated liposomes), liposomaal doxorubicine, Liposomal doxyrubicin, PEG lipsomaal Doxorubicine, lipoomal doxorubicine,Doxorubicine liposomaal= Caelyx, liposomal doxorubicine" "Doxorubicin, Bleomycin, Vinblastine, Dacarbazine (ABVD)",Chemotherapy,"Anthracycline, antitumor antibiotic, vinca alkaloid, alkylating","ABVD" "Doxorubicin, Cyclophosphamide (AC)",Chemotherapy,"Anthracycline, alkylating","AC+, AC" @@ -112,33 +110,30 @@ drug,type,mechanism,synonyms "Etoposide",Chemotherapy,"Alkaloid","" "Etoposide (platinum)",Chemotherapy,"Unknown","platinum etoposide" "Everolimus",Targeted therapy,"mTOR inhibitor","" -"Exemestane",Hormonal therapy,"Aromatase inhibitor","Aromasin,Exemestaan,estemane,Exemetastane" +"Exemestane",Hormonal therapy,"Aromatase inhibitor","Aromasin,Exemestaan,Exemetastane" "Fluoropyrimidine",Chemotherapy,"Pyrimidine (ant)agonist","fluorpyrimidine" "Fluorouracil",Chemotherapy,"Pyrimidine (ant)agonist","Tegafur,Teysuno,5-FU,5-Fluorouracil,5-floururacil,5-fluoracil,capacetabine,flouroucil,Flourouracil,fluor0uracil,Fluoroucil,Capecitabein,Fluoracil, 5-flurauracil, 5 Fluoro-uracil" -"Fluorouracil, Epirubicin, Cyclophosphamide, Docetaxel (FEC-D)",Chemotherapy,"Pyrimidine (ant)agonist, anthracycline, alkylating, taxane","FEC-D" "Fluorouracil, Epirubicin, Cyclophosphamide (FEC)",Chemotherapy,"Pyrimidine (ant)agonist, anthracycline, alkylating","FEC75, FEC" +"Fluorouracil, Epirubicin, Cyclophosphamide, Docetaxel (FEC-D)",Chemotherapy,"Pyrimidine (ant)agonist, anthracycline, alkylating, taxane","FEC-D" "Fluorouracil, Leucovorin Calcium (FU/LV)",Chemotherapy,"Pyrimidine (ant)agonist, folinic acid","FU/LV" +"Fluorouracil,Irinotecan,Leucovorin,Oxaliplatin",Chemotherapy,"Folinic acid, pyrimidine (ant)agonist, topoisomerase inhibitor, platinum","Folfirinox" "Flutamide",Androgen/estrogen deprivation therapy,"Anti-androgen","" -"Leucovorin",Detoxificant,"Folinic acid","folic acid, Folin acid, folinaccid,Foline acid,Foline zuur,folineacid,follincaccid,Folinezuur, folinicacid, Folinic acid" -"Leucovorin, fluorouracil, irinotecan (FOLFIRI)",Chemotherapy,"Folinic acid, pyrimidine (ant)agonist, topoisomerase inhibitor","Folfiri" -"Leucovorin, fluorouracil, irinotecan, oxaliplatin (FOLFIRINOX)",Chemotherapy,"Folinic acid, pyrimidine (ant)agonist, topoisomerase inhibitor, platinum","Folfirinox" -"Leucovorin, fluorouracil, oxaliplatin (FOLFOX)",Chemotherapy,"Folinic acid, pyrimidine (ant)agonist, platinum","Folfox" "Fulvestrant",Hormonal therapy,"Anti-ER","Faslodex" "Gallium(Ga) 68-DOTATATE",Nuclear therapy,"Somatostatin analogue","ga-68 dotatate" -"GDC-0032 or placebo",Randomized trial,"Experimental or placebo","GDC-0032/Placebo" "GDC or placebo",Randomized trial,"Experimental or placebo","GDC/placebo" +"GDC-0032 or placebo",Randomized trial,"Experimental or placebo","GDC-0032/Placebo" "Gefitinib",Targeted therapy,"Anti-EGFR","Gefinitib" "Gemcitabine",Chemotherapy,"Pyrimidine (ant)agonist","Gemicitabine" "Gimeracil",Chemotherapy,"Pyrimidine (ant)agonist","" "Goserelin",Androgen/estrogen deprivation therapy,"GnRH (ant)agonist","goserlrine,Zoladex,Gosareline,Zodalex,Goseriline, Zoladex (restart), Zoladex (Bolla-schema), goselerin" "Granulocyte-macrophage colony-stimulating factor (GM-CSF)",remove,"","GM CSF" -"GSK3359609",Experimental therapy,"Experimental","" "GSK3174998",Experimental therapy,"Experimental","" +"GSK3359609",Experimental therapy,"Experimental","" "HDM201",Experimental therapy,"Anti-HDM2","HDM201" "Hormonal therapy",hormonal therapy,"Unknown","HTx,hormone therapy" "Human papillomavirus vaccine (HPV)",Other,"Other","HPV vaccine" "Human Vascular Endothelial Growth Factor (hVEGF) vaccine",Experimental therapy,"Experimental","hVEGF vaccine" -"hVEGF/RFASE",Experimental therapy,"anti-vEGF","" +"hVEGF/RFASE",Experimental therapy,"Experimental","" "Hyperthermia",Hyperthermia,"Hyperthermia","Synergo" "Hyperthermic Intraperitoneal Chemotherapy (HIPEC)",HIPEC,"HIPEC","HIPEC, Pressurized IntraPeritoneal Aerosol Chemotherapy with Oxaliplatin (belgium)" "Hyperthermic Intraperitoneal Chemotherapy (HIPEC) - COLOPEC",HIPEC,"HIPEC","HIPEC-COLOPEC" @@ -157,13 +152,15 @@ drug,type,mechanism,synonyms "Ketoconazol",remove,"","" "Lanreotide",Hormonal therapy,"Somatostatin analogue","Somatuline, Somatuline = Lanreotide " "Lapatinib",Targeted therapy,"Anti-HER2","" -"LEE0011 or placebo",Randomized trial,"Experimental or placebo","" -"LEE011 or placebo",Randomized trial,"Experimental or placebo","LEE011/Placebo" +"LEE011 or placebo",Randomized trial,"Experimental or placebo","LEE011/Placebo, LEE0011 or placebo" "Lenalidomide",Chemotherapy,"Other","Lenalidomide (HOVON 130)" "Lenvatinib",Targeted therapy,"Multikinase inhibitor","" "Letrozole",Hormonal therapy,"Aromatase inhibitor","Femara,Letrzozol,lezetrol,Lezotrol" -"Letrozole (+ LEE01 or placebo in Monaleesa trial)",Randomized trial,"Aromatase inhibitor or placebo","Letrozole (+ LEE01/placebo in Monaleesa trial)" -"Leuprorelin",Androgen/estrogen deprivation therapy,"GnRH (ant)agonist","leuprolin,Leuproline,Eligard,Lucrin, Lucrin (+ EBRT) in other hospital, Leurporeline" +"Letrozole (+ LEE011 or placebo in Monaleesa trial)",Randomized trial,"Aromatase inhibitor or placebo","Letrozole (+ LEE01/placebo in Monaleesa trial)" +"Leucovorin",Detoxificant,"Folinic acid","folic acid, Folin acid, folinaccid,Foline acid,Foline zuur,folineacid,follincaccid,Folinezuur, folinicacid, Folinic acid" +"Leucovorin, fluorouracil, irinotecan (FOLFIRI)",Chemotherapy,"Folinic acid, pyrimidine (ant)agonist, topoisomerase inhibitor","Folfiri" +"Leucovorin, fluorouracil, oxaliplatin (FOLFOX)",Chemotherapy,"Folinic acid, pyrimidine (ant)agonist, platinum","Folfox" +"Leuprorelin",Androgen/estrogen deprivation therapy,"GnRH (ant)agonist","leuprolin,Leuproline,Eligard,Lucrin, Lucrin (+ EBRT) in other hospital, Leurporeline, Leupropreline, leupropeline" "Leurocristine",Chemotherapy,"Plant alkaloid","" "Liver embolization",Chemotherapy,"","leverembolisatie" "Lomustine",Chemotherapy,"Alkylating","" @@ -173,14 +170,13 @@ drug,type,mechanism,synonyms "Luteinizing hormone-releasing hormone (LHRH) agonists",Androgen/estrogen deprivation therapy,"GnRH (ant)agonist","LHRH,LHRH -antagonist,LHRH analoog,LHRH antagonist,LHRH unknown,LHRH-agonist,LHRH-analogue,LHRH-analoog, LHRH agonist, LHRH (Eligard 6 month depot) " "Lutetium (Lu) -177 DOTATATE",Nuclear therapy,"Somatostatin analogue","2 lutetium dotatate,Lu-177 octreotate,lu-177-dotatate,Lu-177-octreotate,Lutetium,Lutetium 1770octreotaat,Lutetium-177-Octreotaat,Lu-177-octreotaat,Lu-177-HA-DOTATATE, lutetium-octreotaat" "Lutetium (Lu) -177- Prostate-specific membrane antigen (PSMA)",Nuclear therapy,"Anti-PSMA","Lutetium-177-PSMA, Lu-PSMA, PSMA-Lu-177, PSMA-Lu, PSMQ-lu" -"Lutetium (Lu) 177",Nuclear therapy,"Somatostatin analogue","Lutetium 177" -"Lutetium(Lu) 177-Hydroxyapatite (HA) Peptide Receptor Radionuclide Therapy (PRRT)",Nuclear therapy,"Somatostatin analogue","Lutetium 177-HA (PRRT)" +"Lutetium (Lu) 177",Nuclear therapy,"radionuclide","Lutetium 177" +"Lutetium(Lu) 177-Hydroxyapatite (HA) Peptide Receptor Radionuclide Therapy (PRRT)",Nuclear therapy,"radionuclide","Lutetium 177-HA (PRRT)" "LXH254",Experimental therapy,"Experimental","Study15-716; LXH254 1200 mg" "Masitinib",Targeted therapy,"Multikinase inhibitor","" "Mechlorethamine Hydrochloride, Vincristine Sulfate, Procarbazine Hydrochloride, Prednisone (MOPP)",Chemotherapy,"Alkylating, vinca alkaloid, alkylating, glucocorticoid","MOPP" "Medi0562",Immunotherapy,"Monoclonal antibody","" -"Medroxyprogesterone",Hormonal therapy,"Progestogen","Medroxyprogesterion,medroxyprogesteron" -"Medroxyprogesterone acetate",Hormonal therapy,"Progesteron mimic","Provera" +"Medroxyprogesterone acetate",Hormonal therapy,"Progestogen","Medroxyprogesterion,medroxyprogesteron, Provera" "Megestrol",Hormonal therapy,"Progestogen","Megace,megastrolacetaat,Megesterolacetaat,megestra" "Melphalan",Chemotherapy,"Alkylating","melfalan, TNF+Melfalan, Melfalan + TNFalfa " "Mesna",Detoxificant,"Other","Mercaptoethaansulfon-acid" @@ -232,8 +228,8 @@ drug,type,mechanism,synonyms "PF-04518600",Experimental therapy,"Experimental","PF-04518600 (anti-OX40)" "Pimasertib",Targeted therapy,"MEK inhibitor","pimasertinib" "Placebo or ABT-414",Randomized trial,"Unknown","" -"Placebo or ribociclib",Randomized trial,"CDK4/6 inhibitor or placebo","Placebo OR ribociclib" "Placebo or olaparib",Randomized trial,"PARP inhibitor or placebo","Placebo vs olaparib" +"Placebo or ribociclib",Randomized trial,"CDK4/6 inhibitor or placebo","Placebo OR ribociclib" "Placebo or Taselisib",Randomized trial,"PI3K inhibitor or placebo","Placebo/Taselisib" "Pomalidomide",Chemotherapy,"Immune modulator","" "Prednisolone",Other,"Glucocorticoid","prednisolon" @@ -242,17 +238,17 @@ drug,type,mechanism,synonyms "Procarbazine, Lomustine, Vincristine (PCV)",Chemotherapy,"Alkylating, alkylating, vinca alkaloid","PCV" "Prostate-specific membrane antigen (PSMA) - Actinium-225 (Ac-225)",Nuclear therapy,"Anti-PSMA","PSMA-Ac-225 radioligand therapy,PSMA-Ac-225 treatment, PSMA-Ac-225" "Radiofrequency ablation (RFA)",Other,"Radiofrequency ablation","RFA" -"Radium or placebo",Randomized trial,"Nuclear therapy or placebo","radium or placebo" "Radium-223",Nuclear therapy,"Radionuclide","Radium 223 chloride,Radium-233,Radium, Xofigo, Ra223" -"Radium-223 dichloride or placebo",Randomized trial,"Radionuclide or placebo","Radium-223 dichloride/placebo" +"Radium-223 or placebo",Randomized trial,"Nuclear therapy or placebo","radium or placebo, Radium-223 dichloride/placebo" "Radius Investigational Drug Elacestrant (RAD1901)",Experimental therapy,"Experimental","RAD1901" -"Ramucirumab or placebo",Randomized trial,"Anti-VEGFR or placebo","RAMUCIRIMAB/placebo, Ramucirimab/placebo" "Ramucirumab",Targeted therapy,"Anti-VEGFR","Ramucirimab, ramicirumab, Ramicurimab" +"Ramucirumab or placebo",Randomized trial,"Anti-VEGFR or placebo","RAMUCIRIMAB/placebo, Ramucirimab/placebo" "Regorafenib",Targeted therapy,"Multikinase inhibitor","" "Rescuvolin",Detoxificant,"Folinic acid","" "Rhenium",remove,"","" "Ribociclib",Targeted therapy,"CDK4/6 inhibitor","" "Ribociclib or placebo",Randomized trial,"CDK4/6 inhibitor or placebo","" +"Ribociclib or placebo",Randomized trial,"Unknown","study drug (ribocilib or placebo)" "Rilimogene",Experimental therapy,"Experimental","" "Ritonavir",remove,"","" "Rituximab",Targeted therapy,"anti-CD20","MABthera-therapie" @@ -268,7 +264,6 @@ drug,type,mechanism,synonyms "Sorafenib",Targeted therapy,"Multikinase inhibitor","" "SSA",Unknown,"Unknown","" "Streptozocin",Chemotherapy,"Alkylating","streptozocine,streptozosine" -"Ribociclib or placebo",Randomized trial,"Unknown","study drug (ribocilib or placebo)" "Sunitinib",Targeted therapy,"Multikinase inhibitor","Sunitib,Sutent" "SYD985",Experimental therapy,"Experimental","" "Talimogene Laherparepvec (T-VEC)",Experimental therapy,"Oncolytic virus","t-vec, TVEC, T-VEC (Talimogeen)" @@ -288,7 +283,7 @@ drug,type,mechanism,synonyms "Trabectedin",Chemotherapy,"Other","Trabectedine" "Trametinib",Targeted therapy,"MEK inhibitor","" "Transarterial chemoembolization",Chemotherapy,"Other","TACE" -"Trastuzumab",Targeted therapy,"Anti-HER2","T-DM1 (Trastuzumab emtansine),Trastuzumab-emtansine,Zr-89 trastuzumab,herceptin,monotrastuzumab,transuzumab,Trastuzumab mono,TRASTUZUMAB,Trastuzumab-emtansine (T-DM1),TRASTUZUMAB subcutaneous,trastuzum" +"Trastuzumab",Targeted therapy,"Anti-HER2","T-DM1 (Trastuzumab emtansine),Trastuzumab-emtansine,Zr-89 trastuzumab,herceptin,monotrastuzumab,transuzumab,Trastuzumab mono,TRASTUZUMAB,Trastuzumab-emtansine (T-DM1),TRASTUZUMAB subcutaneous" "Tremelimumab",Immunotherapy,"Anti-CTLA-4","" "Trifluridine",Chemotherapy,"Pyrimidine (ant)agonist","Lonsurf,TAS-102,TAS102,Trifluridine-Tipiracil,TAS-201" "Triptorelin",Androgen/estrogen deprivation therapy,"GnRH (ant)agonist","Pamorelin,Pamoreline"