From cd7e3feaa0351a50b518653b705d42ae141e5341 Mon Sep 17 00:00:00 2001 From: bvarner-ebi <95643797+bvarner-ebi@users.noreply.github.com> Date: Wed, 22 Nov 2023 15:45:24 +0000 Subject: [PATCH] Update cl-edit.owl (#2232) Update inadvertently added contributor annotations --- src/ontology/cl-edit.owl | 38 -------------------------------------- 1 file changed, 38 deletions(-) diff --git a/src/ontology/cl-edit.owl b/src/ontology/cl-edit.owl index ac7251aa8..d1bf3287e 100644 --- a/src/ontology/cl-edit.owl +++ b/src/ontology/cl-edit.owl @@ -9033,7 +9033,6 @@ SubClassOf(obo:CL_0000652 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0030187)) # Class: obo:CL_0000653 (podocyte) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "https://doi.org/10.1101/2021.10.10.463829") obo:IAO_0000115 obo:CL_0000653 "A specialized kidney epithelial cell, contained within a glomerulus, that contains \"feet\" that interdigitate with the \"feet\" of other podocytes.") -AnnotationAssertion( obo:CL_0000653 ) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "FMA:70967") oboInOwl:hasBroadSynonym obo:CL_0000653 "epithelial cell of visceral layer of glomerular capsule") AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000653 "BTO:0002295") AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0000653 "FMA:70967") @@ -18330,7 +18329,6 @@ AnnotationAssertion(owl:deprecated obo:CL_0002452 "true"^^xsd:boolean) # Class: obo:CL_0002453 (oligodendrocyte precursor cell) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "GOC:tfm") Annotation(oboInOwl:hasDbXref "PMID:10704434") Annotation(oboInOwl:hasDbXref "PMID:11756508") Annotation(oboInOwl:hasDbXref "PMID:20142420") Annotation(oboInOwl:hasDbXref "PMID:2182078") Annotation(oboInOwl:hasDbXref "PMID:24133281") Annotation(oboInOwl:hasDbXref "PMID:9826671") obo:IAO_0000115 obo:CL_0002453 "A progenitor cell of the central nervous system that can differentiate into oligodendrocytes or type-2 astrocytes. This cell originates from multiple structures within the developing brain including the medial ganglion eminence and the lateral ganglionic eminence. These cells migrate throughout the central nervous system and persist into adulthood where they play an important role in remyelination of injured neurons.") -AnnotationAssertion( obo:CL_0002453 ) AnnotationAssertion( obo:CL_0002453 ) AnnotationAssertion(oboInOwl:creation_date obo:CL_0002453 "2010-11-10T02:51:34Z") AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:2253328") oboInOwl:hasBroadSynonym obo:CL_0002453 "oligodendrocyte-type 2 astrocyte (O-2A) progenitor cell") @@ -19016,7 +19014,6 @@ SubClassOf(obo:CL_0002522 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_000100 # Class: obo:CL_0002523 (mesonephric podocyte) AnnotationAssertion(Annotation( ) Annotation(oboInOwl:hasDbXref "GOC:tfm") obo:IAO_0000115 obo:CL_0002523 "A specialized epithelial cell that contains \"feet\" that interdigitate with the \"feet\" of other glomerular epithelial cells in the mesonephros.") -AnnotationAssertion( obo:CL_0002523 ) AnnotationAssertion( obo:CL_0002523 ) AnnotationAssertion(oboInOwl:creation_date obo:CL_0002523 "2011-02-08T01:58:30Z") AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ZFA:0001674") oboInOwl:hasExactSynonym obo:CL_0002523 "mesonephric glomerular visceral epithelial cell") @@ -21868,7 +21865,6 @@ SubClassOf(obo:CL_0005009 obo:CL_0002518) # Class: obo:CL_0005010 (renal intercalated cell) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "CL:CVS") obo:IAO_0000115 obo:CL_0005010 "A cuboidal epithelial cell of the kidney that regulates acid/base balance.") -AnnotationAssertion( obo:CL_0005010 ) AnnotationAssertion(oboInOwl:hasDbXref obo:CL_0005010 "FMA:86560") AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_0005010 "intercalated cell") AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25632105") rdfs:comment obo:CL_0005010 "Intercalated cells are also called “mitochondria-rich cells”, reflecting the high levels of round mitochondria at their apical pole, or in their cytoplasm, a distribution that is quite different from that of other kidney tubule cells, which accumulated mitochondria around the basolateral membrane. These cells also have numerous irregular apical microvilli compared with the surrounding segment-specific cells. Intercalated cells lack a central cilium, at least in the cortex, which also differentiates them from the adjacent principal cells.") @@ -24698,7 +24694,6 @@ EquivalentClasses(obo:CL_0019032 ObjectIntersectionOf(obo:CL_0002204 ObjectSomeV AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:24051376") Annotation(oboInOwl:hasDbXref "PMID:31300091") Annotation(oboInOwl:hasDbXref "PMID:32016094") obo:IAO_0000115 obo:CL_0700009 "OBSOLETE. A renal beta-intercalated cell that is part of the cortical collecting duct. The medullary collecting duct does not contain the renal beta-intercalated cell type.") AnnotationAssertion(obo:IAO_0100001 obo:CL_0700009 obo:CL_4030005) -AnnotationAssertion( obo:CL_0700009 ) AnnotationAssertion( obo:CL_0700009 "2022-08-26T10:31:29Z"^^xsd:dateTime) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32016094") oboInOwl:hasExactSynonym obo:CL_0700009 "B-IC") AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31300091") oboInOwl:hasExactSynonym obo:CL_0700009 "kidney collecting duct intercalated cell type B") @@ -30494,7 +30489,6 @@ SubClassOf(obo:CL_4029003 obo:CL_4029001) # Class: obo:CL_4030000 (choroidal melanocyte) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31819095") Annotation(oboInOwl:hasDbXref "http://orcid.org/0000-0002-0819-0473") obo:IAO_0000115 obo:CL_4030000 "A melanocyte located in the vascular uvea and involved in photoprotection, regulation of oxidative damage and immune responses.") -AnnotationAssertion( obo:CL_4030000 ) AnnotationAssertion(oboInOwl:creation_date obo:CL_4030000 "2022-01-20T12:59:06Z"^^xsd:dateTime) AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4030000 "uveal melanocyte") AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31819095") Annotation(oboInOwl:hasDbXref "PMID:34082079") rdfs:comment obo:CL_4030000 "Cellular functions and extracellular interactions of choroidal melanocytes are distinct to skin melanocytes. They might have both neuroectodermal as well as mesectodermal origins.") @@ -30504,7 +30498,6 @@ EquivalentClasses(obo:CL_4030000 ObjectIntersectionOf(obo:CL_0000148 ObjectSomeV # Class: obo:CL_4030001 (stromal cell of thymus) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1038/s41467-020-20082-7") obo:IAO_0000115 obo:CL_4030001 "A stromal cell that is part of the thymus.") -AnnotationAssertion( obo:CL_4030001 ) AnnotationAssertion( obo:CL_4030001 "2022-07-08T11:39:38Z"^^xsd:dateTime) AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4030001 "thymic stromal cell") AnnotationAssertion(rdfs:label obo:CL_4030001 "stromal cell of thymus") @@ -30513,7 +30506,6 @@ EquivalentClasses(obo:CL_4030001 ObjectIntersectionOf(obo:CL_0000499 ObjectSomeV # Class: obo:CL_4030002 (effector memory CD45RA-positive, alpha-beta T cell, terminally differentiated) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://orcid.org/0000-0002-2825-0621") obo:IAO_0000115 obo:CL_4030002 "An alpha-beta memory T cell with the phenotype CD45RA-positive.") -AnnotationAssertion( obo:CL_4030002 ) AnnotationAssertion(oboInOwl:creation_date obo:CL_4030002 "2022-02-01T13:04:46Z"^^xsd:dateTime) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16237082") oboInOwl:hasBroadSynonym obo:CL_4030002 "TEMRA") AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16237082") oboInOwl:hasBroadSynonym obo:CL_4030002 "effector memory RA T cell") @@ -30526,7 +30518,6 @@ SubClassOf(obo:CL_4030002 obo:CL_0000791) # Class: obo:CL_4030003 (interstitial cell of thymus) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "doi:10.1038/s41467-020-20082-7") obo:IAO_0000115 obo:CL_4030003 "A cell that makes up the loose connective tissue of the thymus.") -AnnotationAssertion( obo:CL_4030003 "https://orcid.org/0000-0002-1773-2692") AnnotationAssertion( obo:CL_4030003 "2022-07-08T11:48:36Z"^^xsd:dateTime) AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4030003 "thymic interstitial cell") AnnotationAssertion(rdfs:label obo:CL_4030003 "interstitial cell of thymus") @@ -30535,7 +30526,6 @@ SubClassOf(obo:CL_4030003 obo:CL_4030001) # Class: obo:CL_4030004 (thymic nurse cell) AnnotationAssertion(Annotation( ) Annotation(oboInOwl:hasDbXref "https://en.wikipedia.org/wiki/Thymic_nurse_cell") obo:IAO_0000115 obo:CL_4030004 "A large epithelial cell found in the thymus. This cell type may internalize thymocytes through extensions of plasma membrane. The cell surface and cytoplasmic vacuoles of a thymic nurse cell express MHC Class I and MHC Class II antigens. The interaction of these antigens with a developing thymocyte determines whether the thymocyte undergoes positive or negative selection.") -AnnotationAssertion( obo:CL_4030004 ) AnnotationAssertion( obo:CL_4030004 "2022-02-18T12:43:20Z"^^xsd:dateTime) AnnotationAssertion(rdfs:label obo:CL_4030004 "thymic nurse cell") SubClassOf(obo:CL_4030004 obo:CL_0002293) @@ -30543,7 +30533,6 @@ SubClassOf(obo:CL_4030004 obo:CL_0002293) # Class: obo:CL_4030005 (kidney collecting duct beta-intercalated cell) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:24051376") Annotation(oboInOwl:hasDbXref "PMID:31300091") Annotation(oboInOwl:hasDbXref "PMID:32016094") obo:IAO_0000115 obo:CL_4030005 "A renal beta-intercalated cell that is part of the cortical collecting duct. The medullary collecting duct does not contain the renal beta-intercalated cell type.") -AnnotationAssertion( obo:CL_4030005 ) AnnotationAssertion( obo:CL_4030005 "2022-09-14T16:19:11Z"^^xsd:dateTime) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32016094") oboInOwl:hasExactSynonym obo:CL_4030005 "B-IC") AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31300091") oboInOwl:hasExactSynonym obo:CL_4030005 "kidney collecting duct intercalated cell type B") @@ -30553,7 +30542,6 @@ EquivalentClasses(obo:CL_4030005 ObjectIntersectionOf(obo:CL_0002201 ObjectSomeV # Class: obo:CL_4030006 (fallopian tube secretory epithelial cell) AnnotationAssertion(Annotation( ) Annotation(oboInOwl:hasDbXref "https://doi.org/10.1186/1477-7827-7-129") Annotation(oboInOwl:hasDbXref "https://doi.org/10.3390/cells8080933") Annotation(oboInOwl:hasDbXref "https://www.proteinatlas.org/learn/dictionary/normal/fallopian+tube") obo:IAO_0000115 obo:CL_4030006 "An epithelial cell that is part of the fallopian tube epithelium that secretes mucous fluid and oviduct-specific products through the stimulation of estrogen and luteinizing hormone. The fallopian tube secretory cell has approximately the same height as the ciliated cell and is usually a more narrow columnar cell. The nucleus is ovoid and perpendicular to the long axis of the cell. The chromatin is more dense and the nucleolus smaller than that seen in the ciliated cell.") -AnnotationAssertion( obo:CL_4030006 ) AnnotationAssertion( obo:CL_4030006 "2022-03-03T10:39:31Z"^^xsd:dateTime) AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_4030006 "oviduct secretory epithelial cell") AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4030006 "uterine tube secretory epithelial cell") @@ -30565,7 +30553,6 @@ SubClassOf(obo:CL_4030006 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_000388 # Class: obo:CL_4030007 (fallopian tube ciliated cell) AnnotationAssertion(Annotation( ) Annotation(oboInOwl:hasDbXref "PMID:16565155") obo:IAO_0000115 obo:CL_4030007 "An epithelial ciliated cell that is part of the fallopian tube. This cell type is found mainly on the apex of the mucosal folds and contributes, together with peristaltic contractions, to the self-propulsion of spermatozoa, the transport of ovum during ovulation and the transport of the fertilized ovum to the intramural fallopian tube. A fallopian tube ciliated cell has a columnar shape and contains an oval or round nucleus, often located perpendicular or parallel to the long axis of the cell.") -AnnotationAssertion( obo:CL_4030007 ) AnnotationAssertion( obo:CL_4030007 "2022-03-08T12:40:19Z"^^xsd:dateTime) AnnotationAssertion(oboInOwl:hasBroadSynonym obo:CL_4030007 "oviduct ciliated cell") AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4030007 "uterine tube ciliated epithelial cell") @@ -30577,7 +30564,6 @@ SubClassOf(obo:CL_4030007 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_000758 # Class: obo:CL_4030008 (pronephric podocyte) AnnotationAssertion(Annotation( ) Annotation(oboInOwl:hasDbXref "PMID:10322630") obo:IAO_0000115 obo:CL_4030008 "A specialized epithelial cell that contains \"feet\" that interdigitate with the \"feet\" of other glomerular epithelial cells in the pronephros.") -AnnotationAssertion( obo:CL_4030008 ) AnnotationAssertion( obo:CL_4030008 "2022-03-11T14:38:32Z"^^xsd:dateTime) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "ZFA:0001673") oboInOwl:hasExactSynonym obo:CL_4030008 "pronephric glomerular visceral epithelial cell") AnnotationAssertion(rdfs:label obo:CL_4030008 "pronephric podocyte") @@ -30587,7 +30573,6 @@ SubClassOf(obo:CL_4030008 obo:CL_0000653) # Class: obo:CL_4030009 (epithelial cell of proximal tubule segment 1) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31249312") obo:IAO_0000115 obo:CL_4030009 "Epithelial cell that is part of segment 1 (S1) of the proximal tubule epithelium.") -AnnotationAssertion( obo:CL_4030009 ) AnnotationAssertion( obo:CL_4030009 "2022-05-10T13:14:00Z"^^xsd:dateTime) AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4030009 "epithelial cell of segment 1 of proximal tubule") AnnotationAssertion(rdfs:label obo:CL_4030009 "epithelial cell of proximal tubule segment 1") @@ -30596,7 +30581,6 @@ SubClassOf(obo:CL_4030009 obo:CL_0002306) # Class: obo:CL_4030010 (epithelial cell of proximal tubule segment 2) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31249312") obo:IAO_0000115 obo:CL_4030010 "Epithelial cell that is part of segment 2 (S2) of the proximal tubule epithelium.") -AnnotationAssertion( obo:CL_4030010 ) AnnotationAssertion( obo:CL_4030010 "2022-05-10T13:26:13Z"^^xsd:dateTime) AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4030010 "epithelial cell of segment 2 of proximal tubule") AnnotationAssertion(rdfs:label obo:CL_4030010 "epithelial cell of proximal tubule segment 2") @@ -30605,7 +30589,6 @@ SubClassOf(obo:CL_4030010 obo:CL_0002306) # Class: obo:CL_4030011 (epithelial cell of proximal tubule segment 3) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:31249312") obo:IAO_0000115 obo:CL_4030011 "Epithelial cell that is part of segment 3 (S3) of the proximal tubule epithelium.") -AnnotationAssertion( obo:CL_4030011 ) AnnotationAssertion( obo:CL_4030011 "2022-05-10T13:31:06Z"^^xsd:dateTime) AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4030011 "epithelial cell of segment 3 of proximal tubule") AnnotationAssertion(rdfs:label obo:CL_4030011 "epithelial cell of proximal tubule segment 3") @@ -30614,7 +30597,6 @@ SubClassOf(obo:CL_4030011 obo:CL_0002306) # Class: obo:CL_4030012 (kidney loop of Henle short descending thin limb epithelial cell) AnnotationAssertion(Annotation( ) Annotation(oboInOwl:hasDbXref "PMID:33769951") obo:IAO_0000115 obo:CL_4030012 "Epithelial cell of the descending thin limb of the short loop (cortical) nephron limited to the outer medulla (mainly inner strip). It is known in some mammalian species that the short descending limb of the loop of Henle selectively expresses the serine protease Corin, the homeobox TF Uncx, and the urea channel Slc14a2.") -AnnotationAssertion( obo:CL_4030012 ) AnnotationAssertion( obo:CL_4030012 "2022-05-13T11:00:29Z"^^xsd:dateTime) AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4030012 "epithelial cell of the descending thin limb of the short loop of Henle") AnnotationAssertion(rdfs:label obo:CL_4030012 "kidney loop of Henle short descending thin limb epithelial cell") @@ -30624,7 +30606,6 @@ SubClassOf(obo:CL_4030012 obo:CL_1001111) # Class: obo:CL_4030013 (kidney loop of Henle long descending thin limb outer medulla epithelial cell) AnnotationAssertion(Annotation(oboInOwl:hasDbXref ) Annotation(oboInOwl:hasDbXref "PMID:33769951") obo:IAO_0000115 obo:CL_4030013 "Epithelial cell of the descending thin limb of the long loop (juxtamedullary) nephron that spans the outer medulla (inner stripe). It is known in some mammalian species that the long descending limb of the loop of Henle in the outer medulla selectively expresses the secreted activin-antagonist protein follistatin (Fst), the GPI-linked adhesion protein Cdh13, and the protein kinase Stk32a.") -AnnotationAssertion( obo:CL_4030013 ) AnnotationAssertion( obo:CL_4030013 "2022-05-13T11:11:07Z"^^xsd:dateTime) AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4030013 "epithelial cell of the outer medulla of the long descending limb of the loop of Henle") AnnotationAssertion(rdfs:label obo:CL_4030013 "kidney loop of Henle long descending thin limb outer medulla epithelial cell") @@ -30634,7 +30615,6 @@ SubClassOf(obo:CL_4030013 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_000510 # Class: obo:CL_4030014 (kidney loop of Henle long descending thin limb inner medulla epithelial cell) AnnotationAssertion(Annotation(oboInOwl:hasDbXref ) Annotation(oboInOwl:hasDbXref "PMID:33769951") Annotation(oboInOwl:hasDbXref "https://www.ncbi.nlm.nih.gov/gene/8170") obo:IAO_0000115 obo:CL_4030014 "Epithelial cell of the descending thin limb of the long loop (juxtamedullary) nephron that spans the inner medulla. It is known in some mammalian species that the long descending limb of the loop of Henle in the inner medulla selectively expresses the nuclear receptor Nr2e3, the Ig kappa chain Igkc, and the secreted protein dermokine (Dmkn). SLC14A2, which expresses a urea transporter, is also expressed in the inner medulla.") -AnnotationAssertion( obo:CL_4030014 ) AnnotationAssertion( obo:CL_4030014 "2022-05-13T11:16:54Z"^^xsd:dateTime) AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4030014 "epithelial cell of the inner medulla of the long descending limb of the loop of Henle") AnnotationAssertion(rdfs:label obo:CL_4030014 "kidney loop of Henle long descending thin limb inner medulla epithelial cell") @@ -30644,7 +30624,6 @@ SubClassOf(obo:CL_4030014 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_000510 # Class: obo:CL_4030015 (kidney collecting duct alpha-intercalated cell) AnnotationAssertion(Annotation( ) Annotation(oboInOwl:hasDbXref "PMID:31249312") Annotation(oboInOwl:hasDbXref "PMID:9890303") obo:IAO_0000115 obo:CL_4030015 "A renal alpha-intercalated cell that is part of the collecting duct of the renal tubule.") -AnnotationAssertion( obo:CL_4030015 ) AnnotationAssertion( obo:CL_4030015 "2022-05-31T11:15:10Z"^^xsd:dateTime) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9890303") oboInOwl:hasExactSynonym obo:CL_4030015 "kidney collecting duct intercalated cell type A") AnnotationAssertion(rdfs:label obo:CL_4030015 "kidney collecting duct alpha-intercalated cell") @@ -30653,7 +30632,6 @@ EquivalentClasses(obo:CL_4030015 ObjectIntersectionOf(obo:CL_0005011 ObjectSomeV # Class: obo:CL_4030016 (epithelial cell of early distal convoluted tubule) AnnotationAssertion(Annotation(oboInOwl:hasDbXref ) Annotation(oboInOwl:hasDbXref "PMID:24855283") obo:IAO_0000115 obo:CL_4030016 "An epithelial cell located in the early distal convoluted tubule.") -AnnotationAssertion( obo:CL_4030016 ) AnnotationAssertion( obo:CL_4030016 "2022-06-21T12:47:48Z"^^xsd:dateTime) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:24855283") oboInOwl:hasBroadSynonym obo:CL_4030016 "DCT1 cell") AnnotationAssertion(rdfs:label obo:CL_4030016 "epithelial cell of early distal convoluted tubule") @@ -30662,7 +30640,6 @@ EquivalentClasses(obo:CL_4030016 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeV # Class: obo:CL_4030017 (epithelial cell of late distal convoluted tubule) AnnotationAssertion(Annotation(oboInOwl:hasDbXref ) Annotation(oboInOwl:hasDbXref "PMID:24855283") obo:IAO_0000115 obo:CL_4030017 "An epithelial cell located in the late distal convoluted tubule.") -AnnotationAssertion( obo:CL_4030017 ) AnnotationAssertion( obo:CL_4030017 "2022-06-21T13:51:46Z"^^xsd:dateTime) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:24855283") oboInOwl:hasBroadSynonym obo:CL_4030017 "DCT2 cell") AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:24855283") rdfs:comment obo:CL_4030017 "Although mineralocorticoid receptors are expressed throughout the entire [distal convoluted tubule], the DCT2 is sensitive to the actions of aldosterone, because it expresses an enzyme called 11-β hydroxysteroid dehydrogenase 2 (11-βHSD2)") @@ -30672,7 +30649,6 @@ EquivalentClasses(obo:CL_4030017 ObjectIntersectionOf(obo:CL_0000066 ObjectSomeV # Class: obo:CL_4030018 (kidney connecting tubule principal cell) AnnotationAssertion(Annotation(oboInOwl:hasDbXref ) Annotation(oboInOwl:hasDbXref "PMID:27582101") Annotation(oboInOwl:hasDbXref "PMID:31249312") obo:IAO_0000115 obo:CL_4030018 "A renal principal cell located in the connecting tubule.") -AnnotationAssertion( obo:CL_4030018 ) AnnotationAssertion( obo:CL_4030018 "2022-06-27T15:25:10Z"^^xsd:dateTime) AnnotationAssertion(rdfs:label obo:CL_4030018 "kidney connecting tubule principal cell") EquivalentClasses(obo:CL_4030018 ObjectIntersectionOf(obo:CL_0005009 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005097))) @@ -30681,7 +30657,6 @@ SubClassOf(obo:CL_4030018 obo:CL_1000768) # Class: obo:CL_4030019 (kidney connecting tubule intercalated cell) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9890303") obo:IAO_0000115 obo:CL_4030019 "A renal intercalated cell that is part of the renal connecting tubule.") -AnnotationAssertion( obo:CL_4030019 ) AnnotationAssertion( obo:CL_4030019 "2022-06-29T11:25:22Z"^^xsd:dateTime) AnnotationAssertion(rdfs:label obo:CL_4030019 "kidney connecting tubule intercalated cell") EquivalentClasses(obo:CL_4030019 ObjectIntersectionOf(obo:CL_0005010 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005097))) @@ -30690,7 +30665,6 @@ SubClassOf(obo:CL_4030019 obo:CL_1000768) # Class: obo:CL_4030020 (kidney connecting tubule alpha-intercalated cell) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:2254448") Annotation(oboInOwl:hasDbXref "PMID:24937428") Annotation(oboInOwl:hasDbXref "PMID:9890303") obo:IAO_0000115 obo:CL_4030020 "A renal alpha-intercalated cell that is part of the renal connecting tubule.") -AnnotationAssertion( obo:CL_4030020 ) AnnotationAssertion( obo:CL_4030020 "2022-06-29T12:48:43Z"^^xsd:dateTime) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:24937428") oboInOwl:hasExactSynonym obo:CL_4030020 "connecting tubule A-IC") AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9890303") oboInOwl:hasExactSynonym obo:CL_4030020 "kidney connecting tubule intercalated cell type A") @@ -30700,7 +30674,6 @@ EquivalentClasses(obo:CL_4030020 ObjectIntersectionOf(obo:CL_0005011 ObjectSomeV # Class: obo:CL_4030021 (kidney connecting tubule beta-intercalated cell) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:2254448") Annotation(oboInOwl:hasDbXref "PMID:9890303") obo:IAO_0000115 obo:CL_4030021 "A renal beta-intercalated cell that is part of the renal connecting tubule.") -AnnotationAssertion( obo:CL_4030021 ) AnnotationAssertion( obo:CL_4030021 "2022-06-29T14:31:18Z"^^xsd:dateTime) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:32065116") oboInOwl:hasExactSynonym obo:CL_4030021 "connecting tubule B-IC") AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9890303") oboInOwl:hasExactSynonym obo:CL_4030021 "kidney connecting tubule intercalated cell type B") @@ -30710,7 +30683,6 @@ EquivalentClasses(obo:CL_4030021 ObjectIntersectionOf(obo:CL_0002201 ObjectSomeV # Class: obo:CL_4030022 (renal medullary fibroblast) AnnotationAssertion(Annotation(oboInOwl:hasDbXref ) Annotation(oboInOwl:hasDbXref "PMID:10559635") obo:IAO_0000115 obo:CL_4030022 "A fibroblast that is located in the renal medulla interstitium.") -AnnotationAssertion( obo:CL_4030022 ) AnnotationAssertion( obo:CL_4030022 "2022-07-05T12:13:40Z"^^xsd:dateTime) AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4030022 "kidney medullary fibroblast") AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:10559635") rdfs:comment obo:CL_4030022 "It has been noted that inner medullary fibroblasts are involved in the regulation of water and electrolyte homeostasis.") @@ -30720,7 +30692,6 @@ EquivalentClasses(obo:CL_4030022 ObjectIntersectionOf(obo:CL_0000057 ObjectSomeV # Class: obo:CL_4030023 (respiratory hillock cell) AnnotationAssertion(Annotation(oboInOwl:hasDbXref ) Annotation(oboInOwl:hasDbXref "PMID:30069044") Annotation(oboInOwl:hasDbXref "PMID:32726565") Annotation(oboInOwl:hasDbXref "PMID:33442032") obo:IAO_0000115 obo:CL_4030023 "A hillock cell that is located in respiratory epithelium. In some mammalian species, this cell type has been noted to express KRT13 and KRT4 and is postulated to play a role in squamous barrier function and immunomodulation.") -AnnotationAssertion( obo:CL_4030023 ) AnnotationAssertion( obo:CL_4030023 "2022-06-06T08:31:09Z"^^xsd:dateTime) AnnotationAssertion(oboInOwl:hasNarrowSynonym obo:CL_4030023 "hillock cell of respiratory tract") AnnotationAssertion(rdfs:label obo:CL_4030023 "respiratory hillock cell") @@ -30730,7 +30701,6 @@ SubClassOf(obo:CL_4030023 obo:CL_0002368) # Class: obo:CL_4030024 (hillock cell) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30069044") obo:IAO_0000115 obo:CL_4030024 "An epithelial, transitional cell type between basal and secretory; located in stratified, non-ciliated structures (called hillocks) with high cell turnover in epithelium. In some mammalian species, this cell type has been noted to express KRT13 and is postulated to play a role in squamous barrier function and immunomodulation.") -AnnotationAssertion( obo:CL_4030024 ) AnnotationAssertion( obo:CL_4030024 "2022-06-24T14:52:24Z"^^xsd:dateTime) AnnotationAssertion(rdfs:label obo:CL_4030024 "hillock cell") SubClassOf(obo:CL_4030024 obo:CL_0000066) @@ -30738,7 +30708,6 @@ SubClassOf(obo:CL_4030024 obo:CL_0000066) # Class: obo:CL_4030025 (renal cortical fibroblast) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:10559635") obo:IAO_0000115 obo:CL_4030025 "A fibroblast that is located in the renal cortical interstitium.") -AnnotationAssertion( obo:CL_4030025 ) AnnotationAssertion( obo:CL_4030025 "2022-07-05T15:50:17Z"^^xsd:dateTime) AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4030025 "kidney cortical fibroblast") AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:16230044") rdfs:comment obo:CL_4030025 "Renal cortical fibroblasts have key roles in mediating intercellular communication with neighboring/infiltrating cells and extracellular matrix and maintenance of renal tissue architecture. They additionally have an endocrine function in the production of epoetin.") @@ -30748,7 +30717,6 @@ EquivalentClasses(obo:CL_4030025 ObjectIntersectionOf(obo:CL_0000057 ObjectSomeV # Class: obo:CL_4030026 (BEST4+ intestinal epithelial cell, human) AnnotationAssertion(Annotation(oboInOwl:hasDbXref ) Annotation(oboInOwl:hasDbXref "PMID:24223998") Annotation(oboInOwl:hasDbXref "PMID:35176508") obo:IAO_0000115 obo:CL_4030026 "An absorptive epithelial cell of the human intestine expressing bestrophin-4 (BEST4) calcium-activated ion channels.") -AnnotationAssertion( obo:CL_4030026 ) AnnotationAssertion( obo:CL_4030026 "2022-09-07T12:34:20Z"^^xsd:dateTime) AnnotationAssertion(rdfs:label obo:CL_4030026 "BEST4+ intestinal epithelial cell, human") SubClassOf(obo:CL_4030026 obo:CL_0000677) @@ -30758,7 +30726,6 @@ SubClassOf(obo:CL_4030026 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_Q8NFU0)) # Class: obo:CL_4030027 (GABAergic amacrine cell) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "https://doi.org/10.1016/j.cell.2020.08.013") obo:IAO_0000115 obo:CL_4030027 "An amacrine cell that uses GABA as a neurotransmitter.") -AnnotationAssertion( obo:CL_4030027 ) AnnotationAssertion( obo:CL_4030027 "2022-10-17T12:35:11Z"^^xsd:dateTime) AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4030027 "amacrine cell, GABAergic") AnnotationAssertion(rdfs:label obo:CL_4030027 "GABAergic amacrine cell") @@ -30767,7 +30734,6 @@ EquivalentClasses(obo:CL_4030027 ObjectIntersectionOf(obo:CL_0000561 ObjectSomeV # Class: obo:CL_4030028 (glycinergic amacrine cell) AnnotationAssertion(Annotation(obo:IAO_0000115 "https://doi.org/10.1016/j.cell.2020.08.013") obo:IAO_0000115 obo:CL_4030028 "An amacrine cell that uses glycine as a neurotransmitter.") -AnnotationAssertion( obo:CL_4030028 ) AnnotationAssertion( obo:CL_4030028 "2022-10-17T12:40:06Z"^^xsd:dateTime) AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4030028 "amacrine cell, glycinergic") AnnotationAssertion(rdfs:label obo:CL_4030028 "glycinergic amacrine cell") @@ -30776,7 +30742,6 @@ EquivalentClasses(obo:CL_4030028 ObjectIntersectionOf(obo:CL_0000561 ObjectSomeV # Class: obo:CL_4030029 (blood lymphocyte) AnnotationAssertion(Annotation(oboInOwl:hasDbXref ) obo:IAO_0000115 obo:CL_4030029 "A lymphocyte located in blood.") -AnnotationAssertion( obo:CL_4030029 ) AnnotationAssertion( obo:CL_4030029 "2022-11-04T14:40:00Z"^^xsd:dateTime) AnnotationAssertion(rdfs:label obo:CL_4030029 "blood lymphocyte") EquivalentClasses(obo:CL_4030029 ObjectIntersectionOf(obo:CL_0000542 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0000178))) @@ -30794,7 +30759,6 @@ SubClassOf(obo:CL_4030030 ObjectSomeValuesFrom(obo:RO_0001025 obo:UBERON_0013756 # Class: obo:CL_4030031 (interstitial cell) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:24987007") obo:IAO_0000115 obo:CL_4030031 "Any cell that is located within the interstitium between the cells most prominent in defining a given tissue. \"Interstitial cell\" is a morphological term and refers to a variety of cells with differing origins and phenotypes.") -AnnotationAssertion( obo:CL_4030031 ) AnnotationAssertion( obo:CL_4030031 "2022-11-30T14:35:08Z"^^xsd:dateTime) AnnotationAssertion(rdfs:label obo:CL_4030031 "interstitial cell") EquivalentClasses(obo:CL_4030031 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeValuesFrom(obo:BFO_0000050 obo:UBERON_0005169))) @@ -30802,7 +30766,6 @@ EquivalentClasses(obo:CL_4030031 ObjectIntersectionOf(obo:CL_0000000 ObjectSomeV # Class: obo:CL_4030032 (valve interstitial cell) AnnotationAssertion(Annotation(oboInOwl:hasDbXref ) Annotation(oboInOwl:hasDbXref "PMID:25311230") Annotation(oboInOwl:hasDbXref "https://doi.org/10.1098/rsif.2017.0580") Annotation(oboInOwl:hasDbXref "https://doi.org/10.1161/ATVBAHA.120.314789") Annotation(oboInOwl:hasDbXref "https://doi.org/10.1161/JAHA.117.006339") Annotation(oboInOwl:hasDbXref "https://doi.org/10.2353/ajpath.2007.070251") obo:IAO_0000115 obo:CL_4030032 "An interstitial cell that is part of a cardiac valve leaflet. Along with valve endothelial cells, a valve interstitial cell maintains tissue homeostasis for the function of cardiac valves through secreting biochemical signals, matrix proteins and matrix remodeling enzymes.") -AnnotationAssertion( obo:CL_4030032 ) AnnotationAssertion( obo:CL_4030032 "2022-12-06T14:18:45Z"^^xsd:dateTime) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25311230") Annotation(oboInOwl:hasDbXref "PMID:30796046") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasExactSynonym obo:CL_4030032 "VIC") AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4030032 "cardiac valve interstitial cell") @@ -30815,7 +30778,6 @@ SubClassOf(obo:CL_4030032 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0070278)) # Class: obo:CL_4030033 (valve endothelial cell) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25311230") obo:IAO_0000115 obo:CL_4030033 "An endothelial cell that lines a surface of a cardiac valve leaflet. Along with valve interstitial cells, a valve endothelial cell maintains tissue homeostasis for the function of cardiac valves through secreting biochemical signals, matrix proteins and matrix remodeling enzymes.") -AnnotationAssertion( obo:CL_4030033 ) AnnotationAssertion( obo:CL_4030033 "2022-12-09T11:58:49Z"^^xsd:dateTime) AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25311230") Annotation(oboInOwl:hasDbXref "PMID:30796046") Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl:hasExactSynonym obo:CL_4030033 "VEC") AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25311230") oboInOwl:hasExactSynonym obo:CL_4030033 "valvular endothelial cell")