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If you are using Piranha from github, you need to make sure you do a recursive clone. Can you confirm you did that? I think this isn’t needed if you use the release (named with tar.gz, or similar).
No rule to make target 'piranha/src/smithlab_cpp/GenomicRegion.o', needed by `Piranha'. Stop.
This is the whole output
x@compute-0-8 piranha]$ make all
make[1]: Entering directory
/campusdata/x/software/piranha/src' make[2]: Entering directory
/campusdatax/software/piranha/src/progs'make[2]: *** No rule to make target
/campusdata/x/software/piranha/src/smithlab_cpp/GenomicRegion.o', needed by
Piranha'. Stop.make[2]: Leaving directory
/campusdata/x/software/piranha/src/progs' make[1]: *** [all] Error 2 make[1]: Leaving directory
/campusdata/x/software/piranha/src'make: *** [all] Error 2
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