diff --git a/_data/WP4814-bibliography.tsv b/_data/WP4814-bibliography.tsv index 4384842e5..66af4bde3 100644 --- a/_data/WP4814-bibliography.tsv +++ b/_data/WP4814-bibliography.tsv @@ -1,2 +1,3 @@ ID Database Citation +27378692 Pubmed "A recurrent p.Arg92Trp variant in steroidogenic factor-1 (NR5A1) can act as a molecular switch in human sex development. Bashamboo A, Donohoue PA, Vilain E, Rojo S, Calvel P, Seneviratne SN, et al. Hum Mol Genet. 2016 Aug 15;25(16):3446–53. PubMed Europe PMC Scholia" 27915330 Pubmed "Mechanism of Sex Determination in Humans: Insights from Disorders of Sex Development. Bashamboo A, McElreavey K. Sex Dev. 2016;10(5–6):313–25. PubMed Europe PMC Scholia" diff --git a/_data/WP4814-datanodes.tsv b/_data/WP4814-datanodes.tsv index 2201e5a67..11a5e5776 100644 --- a/_data/WP4814-datanodes.tsv +++ b/_data/WP4814-datanodes.tsv @@ -1,5 +1,7 @@ Label Type Identifier Comment Ensembl NCBI gene HGNC UniProt Wikidata ChEBI InChI PubChem ChemSpider HMDB KEGG LipidMaps +ZFPM2 GeneProduct ncbigene:23414 "" ensembl:ENSG00000169946 ncbigene:23414 hgnc.symbol:ZFPM2 uniprot:Q8WW38;uniprot:E7ET52;uniprot:E5RJX0 DHH GeneProduct ensembl:ENSG00000139549 "" ensembl:ENSG00000139549 ncbigene:50846 hgnc.symbol:DHH uniprot:O43323 +CTNNB1 GeneProduct ncbigene:1499 "" ensembl:ENSG00000168036 ncbigene:1499 hgnc.symbol:CTNNB1 uniprot:A0A2R8Y6G0;uniprot:A0A2R8Y804;uniprot:A0A2R8Y815;uniprot:A0A2R8Y5A3;uniprot:C9IZ65;uniprot:A0A2R8Y5C3;uniprot:P35222;uniprot:A0A2R8Y7Z0;uniprot:A0A2R8YG06;uniprot:A0A2R8Y5Z1;uniprot:A0A2R8Y750;uniprot:A0A2R8YCH5;uniprot:A0A024R2Q3;uniprot:A0A2R8Y543;uniprot:B4DGU4 FOXL2 GeneProduct ensembl:ENSG00000183770 "" ensembl:ENSG00000183770 ncbigene:668 hgnc.symbol:FOXL2 uniprot:P58012;uniprot:Q53ZD3 SOX9 GeneProduct ensembl:ENSG00000125398 "" ensembl:ENSG00000125398 ncbigene:6662 hgnc.symbol:SOX9 uniprot:P48436 AMH GeneProduct ensembl:ENSG00000104899 "" ensembl:ENSG00000104899 ncbigene:268 hgnc.symbol:AMH uniprot:P03971 diff --git a/_data/WP5504-bibliography.tsv b/_data/WP5504-bibliography.tsv index 42b228f1b..8cb3d55a1 100644 --- a/_data/WP5504-bibliography.tsv +++ b/_data/WP5504-bibliography.tsv @@ -1,4 +1,6 @@ ID Database Citation 9783642403361 ISBN "Physician’s Guide to the Diagnosis, Treatment, and Follow-Up of Inherited Metabolic Diseases [Internet]. Blau N, Duran M, Gibson KM, Dionisi-Vici C. Springer; 2014. 0 p. Available from: https://books.google.com/books/about/Physician_s_Guide_to_the_Diagnosis_Treat.html?hl=&id=wJRBnwEACAAJ OpenLibrary Worldcat" 37884807 Pubmed "Mitochondrial matrix RTN4IP1/OPA10 is an oxidoreductase for coenzyme Q synthesis. Park I, Kim KE, Kim J, Kim AK, Bae S, Jung M, et al. Nat Chem Biol. 2024 Feb;20(2):221–33. PubMed Europe PMC Scholia" +38199007 Pubmed "Identification of TMEM126A as OXA1L-interacting protein reveals cotranslational quality control in mitochondria. Poerschke S, Oeljeklaus S, Cruz-Zaragoza LD, Schenzielorz A, Dahal D, Hillen HS, et al. Mol Cell. 2024 Jan 18;84(2):345-358.e5. PubMed Europe PMC Scholia" +38891822 Pubmed "Valosin-Containing Protein (VCP): A Review of Its Diverse Molecular Functions and Clinical Phenotypes. Pontifex CS, Zaman M, Fanganiello RD, Shutt TE, Pfeffer G. Int J Mol Sci. 2024 May 22;25(11):5633. PubMed Europe PMC Scholia" 39075050 Pubmed "Deubiquitinase USP9x regulates the proline biosynthesis pathway in non-small cell lung cancer. Becirovic T, Zhang B, Lindskog C, Norberg E, Vakifahmetoglu-Norberg H, Kaminskyy VO, et al. Cell Death Discov. 2024 Jul 29;10(1):342. PubMed Europe PMC Scholia" diff --git a/_data/WP5504-datanodes.tsv b/_data/WP5504-datanodes.tsv index fcb9e7183..8569aa59e 100644 --- a/_data/WP5504-datanodes.tsv +++ b/_data/WP5504-datanodes.tsv @@ -1,8 +1,10 @@ Label Type Identifier Comment Ensembl NCBI gene HGNC UniProt Wikidata ChEBI InChI PubChem ChemSpider HMDB KEGG LipidMaps +arginine Metabolite chebi:29016 "" wikidata:Q27104032 chebi:29016 inchikey:ODKSFYDXXFIFQN-UHFFFAOYSA-N pubchem.compound:59119146;pubchem.compound:232;pubchem.compound:5246487 chemspider:227 hmdb:HMDB0251511 kegg.compound:C02385 NADPH Metabolite chebi:16474 "cofactor to PYCR3" wikidata:Q26841327 chebi:16474 inchikey:ACFIXJIJDZMPPO-NNYOXOHSSA-N pubchem.compound:5884 chemspider:5673 hmdb:HMDB0000221 kegg.compound:C00005 pyrroline-5-carboxylate Metabolite chebi:15893 "AKA P5C" wikidata:Q27098284 chebi:15893 inchikey:DWAKNKKXGALPNW-UHFFFAOYSA-M pubchem.compound:11966213 chemspider:10140206 kegg.compound:C04322 Proline Metabolite chebi:26271 "" wikidata:Q484583 chebi:26271 inchikey:ONIBWKKTOPOVIA-UHFFFAOYSA-N pubchem.compound:25246272;pubchem.compound:614 chemspider:594 hmdb:HMDB0251528 kegg.compound:C16435 biotin Metabolite chebi:15956 "" wikidata:Q181354 chebi:15956 inchikey:YBJHBAHKTGYVGT-ZKWXMUAHSA-N pubchem.compound:171548 chemspider:149962 hmdb:HMDB0000030 kegg.compound:C00120 +ornithine Metabolite chebi:18257 "" wikidata:Q27102952 chebi:18257 inchikey:AHLPHDHHMVZTML-UHFFFAOYSA-N pubchem.compound:134895646;pubchem.compound:389 chemspider:380 kegg.compound:C01602 lipidmaps:LMFA01100057 glutamate Metabolite chebi:14321 "" wikidata:Q27108980 chebi:14321 inchikey:WHUUTDBJXJRKMK-UHFFFAOYSA-M pubchem.compound:4452358;pubchem.compound:4179667;pubchem.compound:4525487 chemspider:3390755 α-Ketoglutarate Metabolite chebi:30915 "aka 2-oxoglutaric acid" wikidata:Q306140 chebi:30915 inchikey:KPGXRSRHYNQIFN-UHFFFAOYSA-N pubchem.compound:156274072;pubchem.compound:51 chemspider:50 hmdb:HMDB0000208 kegg.compound:C00026 AFG3L2 GeneProduct ensembl:ENSG00000141385 "" ensembl:ENSG00000141385 ncbigene:10939 hgnc.symbol:AFG3L2 uniprot:K7EP56;uniprot:Q9Y4W6 @@ -16,6 +18,7 @@ GFER GeneProduct hgnc.symbol:GFER "" ensembl:ENSG00000127554 ncbigene:2671 hgnc. HSPA9 GeneProduct ensembl:ENSG00000113013 "" ensembl:ENSG00000113013 ncbigene:3313 hgnc.symbol:HSPA9 uniprot:A0A7I2V3F7;uniprot:A0A7I2V3D9;uniprot:H0Y8K0;uniprot:A0A384P5G6;uniprot:A0A7I2V4A9;uniprot:D6RCD7;uniprot:A0A3B3ITI4;uniprot:A0A7I2YQQ5;uniprot:A0A7I2V2S7;uniprot:A0A7I2V2G2;uniprot:A0A7I2V2K6;uniprot:P38646;uniprot:H0Y8S0;uniprot:A0A7I2YQB2 HSPD1 GeneProduct ensembl:ENSG00000144381 "" ensembl:ENSG00000144381 ncbigene:3329 hgnc.symbol:HSPD1 uniprot:C9JL19;uniprot:E7ESH4;uniprot:A0A7I2YQ71;uniprot:C9JL25;uniprot:F8WBB1;uniprot:C9J0S9;uniprot:A0A7I2V2X6;uniprot:P10809;uniprot:E7EXB4;uniprot:A0A024R3X4;uniprot:A0A7I2V369;uniprot:A0A7I2V599;uniprot:A0A7I2V5M1;uniprot:A0A7I2YQK6;uniprot:C9JCQ4;uniprot:A0A7I2V5K3 HTRA2 GeneProduct ensembl:ENSG00000115317 "" ensembl:ENSG00000115317 ncbigene:27429 hgnc.symbol:HTRA2 uniprot:A0A384MDW9;uniprot:A0A0C4DG44;uniprot:O43464 +LONP1 GeneProduct uniprot:P36776 "" ensembl:ENSG00000196365 ncbigene:9361 hgnc.symbol:LONP1 uniprot:K7ERS1;uniprot:K7EJE8;uniprot:K7EKE6;uniprot:K7ERR6;uniprot:K7ER27;uniprot:P36776;uniprot:K7EQF8;uniprot:K7ER56 MIPEP GeneProduct ensembl:ENSG00000027001 "" ensembl:ENSG00000027001 ncbigene:4285 hgnc.symbol:MIPEP uniprot:Q99797 PAM16 GeneProduct ensembl:ENSG00000217930 "" ensembl:ENSG00000217930 ncbigene:51025 hgnc.symbol:PAM16 uniprot:Q9Y3D7;uniprot:A0A0B4J298;uniprot:I3L1U7;uniprot:I3L3G8;uniprot:I3L0X9;uniprot:I3L1K9;uniprot:I3L3T0 PITRM1 GeneProduct ensembl:ENSG00000107959 "" ensembl:ENSG00000107959 ncbigene:10531 hgnc.symbol:PITRM1 uniprot:A0A7I2V5C6;uniprot:A0A7I2V3B6;uniprot:A0A7I2YQX5;uniprot:A0A7I2YQT2;uniprot:A0A7I2V3X0;uniprot:A0A7I2V2T0;uniprot:H0Y7L7;uniprot:H0Y4F7;uniprot:A0A7I2V397;uniprot:B4DEU0;uniprot:A0A7I2V4X7;uniprot:A0A0A0MRX9;uniprot:A0A7I2V5R2;uniprot:B1APQ0;uniprot:A0A7I2V449;uniprot:A0A7I2V4N3;uniprot:B1APQ1;uniprot:A0A7I2V5K2;uniprot:A0A7I2V3L7;uniprot:A0A7I2V5H2;uniprot:Q5JRX3 @@ -44,9 +47,12 @@ TXNRD2 GeneProduct ensembl:ENSG00000184470 "" ensembl:ENSG00000184470 ncbigene:1 MICU1 GeneProduct ensembl:ENSG00000107745 "" ensembl:ENSG00000107745 ncbigene:10367 hgnc.symbol:MICU1 uniprot:S4R3V1;uniprot:S4R3W3;uniprot:A0A0U1RRK1;uniprot:A0A286YF11;uniprot:S4R3D7;uniprot:E9PQV6;uniprot:Q9BPX6 ATAD3A GeneProduct ensembl:ENSG00000197785 "" ensembl:ENSG00000197785 ncbigene:55210 hgnc.symbol:ATAD3A uniprot:H0Y2W2;uniprot:Q5SV16;uniprot:Q9NVI7 MICOS13 GeneProduct ensembl:ENSG00000174917 "" ensembl:ENSG00000174917 ncbigene:125988 hgnc.symbol:MICOS13 uniprot:A0A140TA84;uniprot:A0A140TA86;uniprot:Q5XKP0;uniprot:K7EIR2 +UBXN1 Protein uniprot:Q04323 "" ensembl:ENSG00000162191 ncbigene:51035 hgnc.symbol:UBXN1 uniprot:A0A024R539;uniprot:E9PRQ7;uniprot:E9PS08;uniprot:A0A087WTZ5;uniprot:Q04323;uniprot:A0A024R598;uniprot:E9PJ81 +OXA1L Protein uniprot:Q15070 "" ensembl:ENSG00000155463 ncbigene:5018 hgnc.symbol:OXA1L uniprot:E7EVY0;uniprot:H7BZE6;uniprot:J3KNA0;uniprot:Q15070;uniprot:C9JC63;uniprot:A0A087X0L7 YME1L1 Protein uniprot:Q96TA2 "Not in Figure, but added in Table 46.35" ensembl:ENSG00000136758 ncbigene:10730 hgnc.symbol:YME1L1 uniprot:R4GNA5;uniprot:Q6PJ89;uniprot:Q5T8D2;uniprot:Q5T8D1;uniprot:Q96TA2 PYCR3 Protein uniprot:Q53H96 "Active in Cytosol" ensembl:ENSG00000104524 ncbigene:65263 hgnc.symbol:PYCR3 uniprot:A0A087WTU2;uniprot:F8WEI0;uniprot:A0A0A0MQS1;uniprot:B5MD87;uniprot:Q53H96 OPA3? Protein uniprot:Q9H6K4 "" ensembl:ENSG00000125741 ncbigene:80207 hgnc.symbol:OPA3 uniprot:B4DK77;uniprot:Q9H6K4 +UFD1 Protein uniprot:Q92890 "" ensembl:ENSG00000070010 ncbigene:7353 hgnc.symbol:UFD1 uniprot:C9J6N9;uniprot:Q92890;uniprot:C9J7C8;uniprot:Q541A5;uniprot:C9IZG3;uniprot:C9JNP9 COQ3 Protein uniprot:Q9NZJ6 "" ensembl:ENSG00000132423 ncbigene:51805 hgnc.symbol:COQ3 uniprot:F6WGP0;uniprot:Q9NZJ6 MSTO1? Protein uniprot:Q9BUK6 "" ensembl:ENSG00000125459 ncbigene:55154 hgnc.symbol:MSTO1 uniprot:V9GYF2;uniprot:Q9BUK6;uniprot:A0A3B3IUD2 SACS? Protein uniprot:Q9NZJ4 "" ensembl:ENSG00000151835 ncbigene:26278 hgnc.symbol:SACS uniprot:A0A804HHS6;uniprot:A0A804HL98;uniprot:A0A804HK57;uniprot:H0Y6M8;uniprot:A0A804HKY6;uniprot:A0A804HIQ1;uniprot:A0A804HJS2;uniprot:B2REB0;uniprot:A0A804HLL1;uniprot:Q9NZJ4;uniprot:A0A804HK18;uniprot:A0A804HKB3;uniprot:A0A804HIG5;uniprot:A0A804HLK7;uniprot:A0A804HIU0 @@ -59,3 +65,10 @@ PYCR1 Protein uniprot:P32322 "Active in Cytosol" ensembl:ENSG00000183010 ncbigen PYCR2 Protein uniprot:Q96C36 "Active in Cytosol" ensembl:ENSG00000143811 ncbigene:29920 hgnc.symbol:PYCR2 uniprot:A0A087WX69;uniprot:A0A0S2Z5U6;uniprot:A0A087WTV6;uniprot:A0A087WZF0;uniprot:Q96C36 OPA3 Protein uniprot:Q9H6K4 "" ensembl:ENSG00000125741 ncbigene:80207 hgnc.symbol:OPA3 uniprot:B4DK77;uniprot:Q9H6K4 MSTO1 Protein uniprot:Q9BUK6 "" ensembl:ENSG00000125459 ncbigene:55154 hgnc.symbol:MSTO1 uniprot:V9GYF2;uniprot:Q9BUK6;uniprot:A0A3B3IUD2 +LONP1 Protein uniprot:P36776 "" ensembl:ENSG00000196365 ncbigene:9361 hgnc.symbol:LONP1 uniprot:K7ERS1;uniprot:K7EJE8;uniprot:K7EKE6;uniprot:K7ERR6;uniprot:K7ER27;uniprot:P36776;uniprot:K7EQF8;uniprot:K7ER56 +NPLOC4 Protein uniprot:Q8TAT6 "AKA NPL4" ensembl:ENSG00000182446 ncbigene:55666 hgnc.symbol:NPLOC4 uniprot:Q8TAT6;uniprot:A0A0D9SFI9;uniprot:I3L4U9;uniprot:I3L4S2;uniprot:K7EJN1;uniprot:I3L283;uniprot:I3L281;uniprot:I3L3I1;uniprot:A0A024R8R4;uniprot:I3L0W3 +p47 Protein uniprot:P08567 "" ensembl:ENSG00000115956 ncbigene:5341 hgnc.symbol:PLEK uniprot:P08567 +MFN1 Protein uniprot:Q8IWA4 "" ensembl:ENSG00000171109 ncbigene:55669 hgnc.symbol:MFN1 uniprot:C9JQT7;uniprot:Q8IWA4;uniprot:H7C5H5;uniprot:C9JXQ1 +UBXD1/UBXN6 Protein uniprot:Q9BZV1 "" ensembl:ENSG00000167671 ncbigene:80700 hgnc.symbol:UBXN6 uniprot:K7ELN1;uniprot:K7EP32;uniprot:Q9BZV1;uniprot:K7EJ02 +MCL1 Protein uniprot:Q07820 "" ensembl:ENSG00000143384 ncbigene:574406;ncbigene:4170 hgnc.symbol:MCL1 uniprot:Q07820;uniprot:A0A087WT64;uniprot:A0A7I2V2W2 +MARCHF5 Protein uniprot:Q9NX47 "MITOL/March5" ensembl:ENSG00000198060 ncbigene:54708 hgnc.symbol:MARCHF5 uniprot:Q9NX47 diff --git a/_pathways/WP3611.md b/_pathways/WP3611.md index 6148a2ff7..ba864ad0e 100644 --- a/_pathways/WP3611.md +++ b/_pathways/WP3611.md @@ -23,19 +23,20 @@ citedin: title: 'A Practical Strategy for Exploring the Pharmacological Mechanism of Luteolin Against COVID-19/Asthma Comorbidity: Findings of System Pharmacology and Bioinformatics Analysis (2024)' +communities: [] description: Photodynamic therapy may induce an acute stress response mediated by mitogen-activated protein kinase kinase kinase 5 (MAP3K5), its downstream MAPKs that target c-Jun N-terminal kinase (JNK, MAPK8) and p38MAPK, and the transcription factors of the activator protein 1 (AP-1) family. -last-edited: 2021-12-09 +last-edited: 2024-12-20 ndex: 274026a0-8b67-11eb-9e72-0ac135e8bacf organisms: - Homo sapiens redirect_from: - /index.php/Pathway:WP3611 - /instance/WP3611 -- /instance/WP3611_r120501 -revision: r120501 +- /instance/WP3611_r136148 +revision: r136148 schema-jsonld: - '@context': https://schema.org/ '@id': https://wikipathways.github.io/pathways/WP3611.html diff --git a/_pathways/WP4030.md b/_pathways/WP4030.md index 1c4be46da..ec00c6456 100644 --- a/_pathways/WP4030.md +++ b/_pathways/WP4030.md @@ -30,15 +30,15 @@ description: 'The short-chain fatty acids (SCFA) acetate, propionate and butyrat transporter type 4 (GLUT4) and decreases glycolysis. In addition to AMPK activation, SCFA might also induce peroxisome proliferator activated receptor delta (PPARD) expression, another process contributing to enhanced fat oxidation levels. ' -last-edited: 2024-12-19 +last-edited: 2024-12-20 ndex: 331ac03a-8b69-11eb-9e72-0ac135e8bacf organisms: - Homo sapiens redirect_from: - /index.php/Pathway:WP4030 - /instance/WP4030 -- /instance/WP4030_r136104 -revision: r136104 +- /instance/WP4030_r136145 +revision: r136145 schema-jsonld: - '@context': https://schema.org/ '@id': https://wikipathways.github.io/pathways/WP4030.html diff --git a/_pathways/WP4814.md b/_pathways/WP4814.md index ce162c8fd..dad45a249 100644 --- a/_pathways/WP4814.md +++ b/_pathways/WP4814.md @@ -1,38 +1,43 @@ --- annotations: +- id: CL:0000178 + parent: native cell + type: Cell Type Ontology + value: Leydig cell +- id: DOID:1923 + type: Disease Ontology + value: disorder of sexual development - id: PW:0000003 parent: signaling pathway type: Pathway Ontology value: signaling pathway -- id: DOID:1923 - type: Disease Ontology - value: disorder of sexual development authors: - JenG - Fehrhart - Eweitz +- Khanspers citedin: - link: 10.1186/s13148-023-01612-8 title: 'Methylation analysis by targeted bisulfite sequencing in large for gestational age (LGA) newborns: the LARGAN cohort (2024)' communities: - RareDiseases -description: This pathway describes the sex determination in a fetus. For the male +description: 'This pathway describes the sex determination in a fetus. For the male development the SRY gene plays an important role, leading to the SOX9 expression which will then stimulate AMH expression and testis development. In adults DMRT1 and SOX9 inhibit the FOXL2 gene, maintaining the male sex determination. For the female development the WNT4 and RSPO1 signaling pathways lead to beta-catenin accumulation which inhibits SOX9 and the development of ovaries. In adults, Foxl2 repress Sox9 - expression to maintain ovarian identity. -last-edited: 2021-05-07 + expression to maintain ovarian identity. ' +last-edited: 2024-12-20 ndex: b6c7699b-8b6d-11eb-9e72-0ac135e8bacf organisms: - Homo sapiens redirect_from: - /index.php/Pathway:WP4814 - /instance/WP4814 -- /instance/WP4814_r116554 -revision: r116554 +- /instance/WP4814_r136147 +revision: r136147 schema-jsonld: - '@context': https://schema.org/ '@id': https://wikipathways.github.io/pathways/WP4814.html @@ -40,15 +45,16 @@ schema-jsonld: creator: '@type': Organization name: WikiPathways - description: This pathway describes the sex determination in a fetus. For the male - development the SRY gene plays an important role, leading to the SOX9 expression + description: 'This pathway describes the sex determination in a fetus. For the + male development the SRY gene plays an important role, leading to the SOX9 expression which will then stimulate AMH expression and testis development. In adults DMRT1 and SOX9 inhibit the FOXL2 gene, maintaining the male sex determination. For the female development the WNT4 and RSPO1 signaling pathways lead to beta-catenin accumulation which inhibits SOX9 and the development of ovaries. In adults, Foxl2 - repress Sox9 expression to maintain ovarian identity. + repress Sox9 expression to maintain ovarian identity. ' keywords: - AMH + - CTNNB1 - DHH - DMRT1 - FGF9 @@ -62,6 +68,7 @@ schema-jsonld: - SRY - WNT4 - WT1 + - ZFPM2 license: CC0 name: Somatic sex determination seo: CreativeWork diff --git a/_pathways/WP5504.md b/_pathways/WP5504.md index 300775a31..37d34e57d 100644 --- a/_pathways/WP5504.md +++ b/_pathways/WP5504.md @@ -1,13 +1,13 @@ --- annotations: -- id: PW:0000013 - parent: disease pathway - type: Pathway Ontology - value: disease pathway - id: PW:0001669 parent: disease pathway type: Pathway Ontology value: mitochondrial disease pathway +- id: PW:0000013 + parent: disease pathway + type: Pathway Ontology + value: disease pathway authors: - Egonw - DeSl @@ -20,15 +20,15 @@ description: This pathway lists several genes involved in mechanisms involved in pathway was inspired by Figure 46.1 of Edition 5, Chapter 46 of the book of Blau (ISBN 9783030677268). Genes linked to a disease in this book chapter are depicted in red. -last-edited: 2024-12-19 +last-edited: 2024-12-20 ndex: null organisms: - Homo sapiens redirect_from: - /index.php/Pathway:WP5504 - /instance/WP5504 -- /instance/WP5504_r136128 -revision: r136128 +- /instance/WP5504_r136141 +revision: r136141 schema-jsonld: - '@context': https://schema.org/ '@id': https://wikipathways.github.io/pathways/WP5504.html @@ -58,7 +58,11 @@ schema-jsonld: - HSPA9 - HSPD1 - HTRA2 + - LONP1 + - MARCHF5 + - MCL1 - MFF + - MFN1 - MFN2 - MICOS13 - MICU1 @@ -66,9 +70,11 @@ schema-jsonld: - MSTO1 - MSTO1? - NADPH + - NPLOC4 - OPA1 - OPA3 - OPA3? + - OXA1L - PAM16 - PINK1 - PITRM1 @@ -93,12 +99,18 @@ schema-jsonld: - TRAK1 - TXN2 - TXNRD2 + - UBXD1/UBXN6 + - UBXN1 + - UFD1 - USP9X - VCP - 'XPNPEP3 ' - YME1L1 + - arginine - biotin - glutamate + - ornithine + - p47 - pyrroline-5-carboxylate - α-Ketoglutarate license: CC0 diff --git a/_pathways/WP5505.md b/_pathways/WP5505.md index 00f73ea95..0cb62f0d0 100644 --- a/_pathways/WP5505.md +++ b/_pathways/WP5505.md @@ -1,13 +1,13 @@ --- annotations: -- id: PW:0000002 - parent: classic metabolic pathway - type: Pathway Ontology - value: classic metabolic pathway - id: PW:0000161 parent: classic metabolic pathway type: Pathway Ontology value: glycosylphosphatidylinositol anchor biosynthetic pathway +- id: PW:0000002 + parent: classic metabolic pathway + type: Pathway Ontology + value: classic metabolic pathway authors: - Egonw - Mkutmon @@ -15,7 +15,7 @@ citedin: '' communities: - MetaKids description: Literature reference -last-edited: 2024-12-19 +last-edited: 2024-12-20 ndex: null organisms: - Homo sapiens diff --git a/assets/img/WP3611/WP3611-thumb.png b/assets/img/WP3611/WP3611-thumb.png index 9ab94a8c5..675859c06 100644 Binary files a/assets/img/WP3611/WP3611-thumb.png and b/assets/img/WP3611/WP3611-thumb.png differ diff --git a/assets/img/WP4030/WP4030-thumb.png b/assets/img/WP4030/WP4030-thumb.png index 4bbdfbd15..dcf3bc4e4 100644 Binary files a/assets/img/WP4030/WP4030-thumb.png and b/assets/img/WP4030/WP4030-thumb.png differ diff --git a/assets/img/WP4814/WP4814-thumb.png b/assets/img/WP4814/WP4814-thumb.png index 1942da94b..efae30a44 100644 Binary files a/assets/img/WP4814/WP4814-thumb.png and b/assets/img/WP4814/WP4814-thumb.png differ diff --git a/assets/img/WP5504/WP5504-thumb.png b/assets/img/WP5504/WP5504-thumb.png index 3c46b3bda..21413b2ff 100644 Binary files a/assets/img/WP5504/WP5504-thumb.png and b/assets/img/WP5504/WP5504-thumb.png differ