diff --git a/.github/workflows/pre-commit.yml b/.github/workflows/pre-commit.yml
new file mode 100644
index 0000000..0f06e16
--- /dev/null
+++ b/.github/workflows/pre-commit.yml
@@ -0,0 +1,33 @@
+# Generated from:
+# https://github.com/zopefoundation/meta/tree/master/config/pure-python
+name: pre-commit
+
+on:
+  pull_request:
+  push:
+    branches:
+    - master
+  # Allow to run this workflow manually from the Actions tab
+  workflow_dispatch:
+
+env:
+  FORCE_COLOR: 1
+
+jobs:
+  pre-commit:
+    name: linting
+    runs-on: ubuntu-latest
+    steps:
+    - uses: actions/checkout@v4
+    - uses: actions/setup-python@v5
+      with:
+        python-version: 3.x
+    - uses: pre-commit/action@v3.0.1
+      with:
+        extra_args: --all-files --show-diff-on-failure
+      env:
+        PRE_COMMIT_COLOR: always
+    - uses: pre-commit-ci/lite-action@v1.0.2
+      if: always()
+      with:
+        msg: Apply pre-commit code formatting
diff --git a/.github/workflows/tests.yml b/.github/workflows/tests.yml
index 8b3bcbc..50629dd 100644
--- a/.github/workflows/tests.yml
+++ b/.github/workflows/tests.yml
@@ -17,33 +17,32 @@ jobs:
       fail-fast: false
       matrix:
         os:
-        - ["ubuntu", "ubuntu-20.04"]
+        - ["ubuntu", "ubuntu-latest"]
         config:
         # [Python version, tox env]
-        - ["3.9",   "release-check"]
-        - ["3.9",   "lint"]
-        - ["3.7",   "py37"]
-        - ["3.8",   "py38"]
-        - ["3.9",   "py39"]
-        - ["3.10",  "py310"]
-        - ["3.11",  "py311"]
-        - ["3.12",  "py312"]
-        - ["3.13.0-alpha - 3.13.0",  "py313"]
-        - ["pypy-3.9", "pypy3"]
-        - ["3.9",   "docs"]
-        - ["3.9",   "coverage"]
+        - ["3.11", "release-check"]
+        - ["3.8", "py38"]
+        - ["3.9", "py39"]
+        - ["3.10", "py310"]
+        - ["3.11", "py311"]
+        - ["3.12", "py312"]
+        - ["3.13", "py313"]
+        - ["pypy-3.10", "pypy3"]
+        - ["3.11", "docs"]
+        - ["3.11", "coverage"]
 
     runs-on: ${{ matrix.os[1] }}
     if: github.event_name != 'pull_request' || github.event.pull_request.head.repo.full_name != github.event.pull_request.base.repo.full_name
     name: ${{ matrix.config[1] }}
     steps:
-    - uses: actions/checkout@v3
+    - uses: actions/checkout@v4
     - name: Set up Python
-      uses: actions/setup-python@v4
+      uses: actions/setup-python@v5
       with:
         python-version: ${{ matrix.config[0] }}
+        allow-prereleases: true
     - name: Pip cache
-      uses: actions/cache@v3
+      uses: actions/cache@v4
       with:
         path: ~/.cache/pip
         key: ${{ runner.os }}-pip-${{ matrix.config[0] }}-${{ hashFiles('setup.*', 'tox.ini') }}
@@ -55,7 +54,11 @@ jobs:
         python -m pip install --upgrade pip
         pip install tox
     - name: Test
+      if: ${{ !startsWith(runner.os, 'Mac') }}
       run: tox -e ${{ matrix.config[1] }}
+    - name: Test (macOS)
+      if: ${{ startsWith(runner.os, 'Mac') }}
+      run: tox -e ${{ matrix.config[1] }}-universal2
     - name: Coverage
       if: matrix.config[1] == 'coverage'
       run: |
diff --git a/.meta.toml b/.meta.toml
index 4f73e55..c213e4f 100644
--- a/.meta.toml
+++ b/.meta.toml
@@ -2,14 +2,14 @@
 # https://github.com/zopefoundation/meta/tree/master/config/pure-python
 [meta]
 template = "pure-python"
-commit-id = "6f8d8c51"
+commit-id = "85622de1"
 
 [python]
 with-pypy = true
 with-docs = true
 with-sphinx-doctests = true
 with-windows = false
-with-future-python = true
+with-future-python = false
 with-macos = false
 
 [tox]
diff --git a/.pre-commit-config.yaml b/.pre-commit-config.yaml
new file mode 100644
index 0000000..7ab398c
--- /dev/null
+++ b/.pre-commit-config.yaml
@@ -0,0 +1,28 @@
+# Generated from:
+# https://github.com/zopefoundation/meta/tree/master/config/pure-python
+minimum_pre_commit_version: '3.6'
+repos:
+  - repo: https://github.com/pycqa/isort
+    rev: "5.13.2"
+    hooks:
+    - id: isort
+  - repo: https://github.com/hhatto/autopep8
+    rev: "v2.3.1"
+    hooks:
+    - id: autopep8
+      args: [--in-place, --aggressive, --aggressive]
+  - repo: https://github.com/asottile/pyupgrade
+    rev: v3.17.0
+    hooks:
+    - id: pyupgrade
+      args: [--py38-plus]
+  - repo: https://github.com/isidentical/teyit
+    rev: 0.4.3
+    hooks:
+    - id: teyit
+  - repo: https://github.com/PyCQA/flake8
+    rev: "7.1.1"
+    hooks:
+    - id: flake8
+      additional_dependencies:
+        - flake8-debugger == 4.1.2
diff --git a/CHANGES.rst b/CHANGES.rst
index c4c685b..2c6b4b6 100644
--- a/CHANGES.rst
+++ b/CHANGES.rst
@@ -2,10 +2,12 @@
  Changes
 =========
 
-4.1 (unreleased)
+5.0 (unreleased)
 ================
 
-- Nothing changed yet.
+- Add final support for Python 3.13.
+
+- Drop support for Python 3.7.
 
 
 4.0 (2023-11-13)
diff --git a/MANIFEST.in b/MANIFEST.in
index a1103d6..a8b9c14 100644
--- a/MANIFEST.in
+++ b/MANIFEST.in
@@ -5,6 +5,7 @@ include *.rst
 include *.txt
 include buildout.cfg
 include tox.ini
+include .pre-commit-config.yaml
 
 recursive-include docs *.py
 recursive-include docs *.rst
diff --git a/docs/conf.py b/docs/conf.py
index 8abf14b..8af5f4d 100644
--- a/docs/conf.py
+++ b/docs/conf.py
@@ -1,9 +1,8 @@
-# -*- coding: utf-8 -*-
 #
 # transaction documentation build configuration file, created by
 # sphinx-quickstart on Wed May 16 16:43:53 2012.
 #
-# This file is execfile()d with the current directory set to its containing dir.
+# This file is execfile()d with the current directory set to its containing dir
 #
 # Note that not all possible configuration values are present in this
 # autogenerated file.
@@ -11,26 +10,29 @@
 # All configuration values have a default; values that are commented out
 # serve to show the default.
 
-import sys, os
+import os
+import sys
+
 import pkg_resources
 
+
 # If extensions (or modules to document with autodoc) are in another directory,
 # add these directories to sys.path here. If the directory is relative to the
 # documentation root, use os.path.abspath to make it absolute, like shown here.
-#sys.path.insert(0, os.path.abspath('.'))
+# sys.path.insert(0, os.path.abspath('.'))
 sys.path.append(os.path.abspath('../'))
 rqmt = pkg_resources.require('transaction')[0]
 
-# -- General configuration -----------------------------------------------------
+# -- General configuration -----------------------------------------------
 
 # If your documentation needs a minimal Sphinx version, state it here.
-#needs_sphinx = '1.0'
+# needs_sphinx = '1.0'
 
 # 1.8 was the last version that runs on Python 2; 2.0+ requires Python 3.
 # `autodoc_default_options` was new in 1.8
 needs_sphinx = "1.8"
 
-# Add any Sphinx extension module names here, as strings. They can be extensions
+# Add any Sphinx extension module names here as strings. They can be extensions
 # coming with Sphinx (named 'sphinx.ext.*') or your custom ones.
 extensions = [
     'sphinx.ext.autodoc',
@@ -48,14 +50,14 @@
 source_suffix = '.rst'
 
 # The encoding of source files.
-#source_encoding = 'utf-8-sig'
+# source_encoding = 'utf-8-sig'
 
 # The master toctree document.
 master_doc = 'index'
 
 # General information about the project.
-project = u'transaction'
-copyright = u'2012, Zope Foundation Contributors'
+project = 'transaction'
+copyright = '2012-2024, Zope Foundation Contributors'
 
 # The version info for the project you're documenting, acts as replacement for
 # |version| and |release|, also used in various other places throughout the
@@ -68,40 +70,41 @@
 
 # The language for content autogenerated by Sphinx. Refer to documentation
 # for a list of supported languages.
-#language = None
+# language = None
 
 # There are two options for replacing |today|: either, you set today to some
 # non-false value, then it is used:
-#today = ''
+# today = ''
 # Else, today_fmt is used as the format for a strftime call.
-#today_fmt = '%B %d, %Y'
+# today_fmt = '%B %d, %Y'
 
 # List of patterns, relative to source directory, that match files and
 # directories to ignore when looking for source files.
 exclude_patterns = ['_build']
 
-# The reST default role (used for this markup: `text`) to use for all documents.
+# The reST default role (used for this markup: `text`) to use for all
+# documents.
 default_role = 'obj'
 
 # If true, '()' will be appended to :func: etc. cross-reference text.
-#add_function_parentheses = True
+# add_function_parentheses = True
 
 # If true, the current module name will be prepended to all description
 # unit titles (such as .. function::).
-#add_module_names = True
+# add_module_names = True
 
 # If true, sectionauthor and moduleauthor directives will be shown in the
 # output. They are ignored by default.
-#show_authors = False
+# show_authors = False
 
 # The name of the Pygments (syntax highlighting) style to use.
 pygments_style = 'sphinx'
 
 # A list of ignored prefixes for module index sorting.
-#modindex_common_prefix = []
+# modindex_common_prefix = []
 
 
-# -- Options for HTML output ---------------------------------------------------
+# -- Options for HTML output ---------------------------------------------
 
 # The theme to use for HTML and HTML Help pages.  See the documentation for
 # a list of builtin themes.
@@ -110,26 +113,26 @@
 # Theme options are theme-specific and customize the look and feel of a theme
 # further.  For a list of options available for each theme, see the
 # documentation.
-#html_theme_options = {}
+# html_theme_options = {}
 
 # Add any paths that contain custom themes here, relative to this directory.
-#html_theme_path = []
+# html_theme_path = []
 
 # The name for this set of Sphinx documents.  If None, it defaults to
 # "<project> v<release> documentation".
-#html_title = None
+# html_title = None
 
 # A shorter title for the navigation bar.  Default is the same as html_title.
-#html_short_title = None
+# html_short_title = None
 
 # The name of an image file (relative to this directory) to place at the top
 # of the sidebar.
-#html_logo = None
+# html_logo = None
 
 # The name of an image file (within the static path) to use as favicon of the
 # docs.  This file should be a Windows icon file (.ico) being 16x16 or 32x32
 # pixels large.
-#html_favicon = None
+# html_favicon = None
 
 # Add any paths that contain custom static files (such as style sheets) here,
 # relative to this directory. They are copied after the builtin static files,
@@ -138,123 +141,131 @@
 
 # If not '', a 'Last updated on:' timestamp is inserted at every page bottom,
 # using the given strftime format.
-#html_last_updated_fmt = '%b %d, %Y'
+# html_last_updated_fmt = '%b %d, %Y'
 
 # If true, SmartyPants will be used to convert quotes and dashes to
 # typographically correct entities.
-#html_use_smartypants = True
+# html_use_smartypants = True
 
 # Custom sidebar templates, maps document names to template names.
-#html_sidebars = {}
-html_sidebars = { '**': ['globaltoc.html', 'relations.html', 'sourcelink.html', 'searchbox.html'], }
+# html_sidebars = {}
+html_sidebars = {'**': ['globaltoc.html',
+                        'relations.html',
+                        'sourcelink.html',
+                        'searchbox.html'],
+                 }
 
 # Additional templates that should be rendered to pages, maps page names to
 # template names.
-#html_additional_pages = {}
+# html_additional_pages = {}
 
 # If false, no module index is generated.
-#html_domain_indices = True
+# html_domain_indices = True
 
 # If false, no index is generated.
-#html_use_index = True
+# html_use_index = True
 
 # If true, the index is split into individual pages for each letter.
-#html_split_index = False
+# html_split_index = False
 
 # If true, links to the reST sources are added to the pages.
-#html_show_sourcelink = True
+# html_show_sourcelink = True
 
 # If true, "Created using Sphinx" is shown in the HTML footer. Default is True.
-#html_show_sphinx = True
+# html_show_sphinx = True
 
 # If true, "(C) Copyright ..." is shown in the HTML footer. Default is True.
-#html_show_copyright = True
+# html_show_copyright = True
 
 # If true, an OpenSearch description file will be output, and all pages will
 # contain a <link> tag referring to it.  The value of this option must be the
 # base URL from which the finished HTML is served.
-#html_use_opensearch = ''
+# html_use_opensearch = ''
 
 # This is the file name suffix for HTML files (e.g. ".xhtml").
-#html_file_suffix = None
+# html_file_suffix = None
 
 # Output file base name for HTML help builder.
 htmlhelp_basename = 'transactiondoc'
 
 
-# -- Options for LaTeX output --------------------------------------------------
+# -- Options for LaTeX output --------------------------------------------
 
 latex_elements = {
-# The paper size ('letterpaper' or 'a4paper').
-#'papersize': 'letterpaper',
+    # The paper size ('letterpaper' or 'a4paper').
+    # 'papersize': 'letterpaper',
 
-# The font size ('10pt', '11pt' or '12pt').
-#'pointsize': '10pt',
+    # The font size ('10pt', '11pt' or '12pt').
+    # 'pointsize': '10pt',
 
-# Additional stuff for the LaTeX preamble.
-#'preamble': '',
+    # Additional stuff for the LaTeX preamble.
+    # 'preamble': '',
 }
 
 # Grouping the document tree into LaTeX files. List of tuples
-# (source start file, target name, title, author, documentclass [howto/manual]).
+# (source start file, target name, title, author, documentclass [howto/manual])
 latex_documents = [
-  ('index', 'transaction.tex', u'transaction Documentation',
-   u'Zope Foundation Contributors', 'manual'),
+    ('index', 'transaction.tex', 'transaction Documentation',
+     'Zope Foundation Contributors', 'manual'),
 ]
 
 # The name of an image file (relative to this directory) to place at the top of
 # the title page.
-#latex_logo = None
+# latex_logo = None
 
 # For "manual" documents, if this is true, then toplevel headings are parts,
 # not chapters.
-#latex_use_parts = False
+# latex_use_parts = False
 
 # If true, show page references after internal links.
-#latex_show_pagerefs = False
+# latex_show_pagerefs = False
 
 # If true, show URL addresses after external links.
-#latex_show_urls = False
+# latex_show_urls = False
 
 # Documents to append as an appendix to all manuals.
-#latex_appendices = []
+# latex_appendices = []
 
 # If false, no module index is generated.
-#latex_domain_indices = True
+# latex_domain_indices = True
 
 
-# -- Options for manual page output --------------------------------------------
+# -- Options for manual page output --------------------------------------
 
 # One entry per manual page. List of tuples
 # (source start file, name, description, authors, manual section).
 man_pages = [
-    ('index', 'transaction', u'transaction Documentation',
-     [u'Zope Foundation Contributors'], 1)
+    ('index', 'transaction', 'transaction Documentation',
+     ['Zope Foundation Contributors'], 1)
 ]
 
 # If true, show URL addresses after external links.
-#man_show_urls = False
+# man_show_urls = False
 
 
-# -- Options for Texinfo output ------------------------------------------------
+# -- Options for Texinfo output ------------------------------------------
 
 # Grouping the document tree into Texinfo files. List of tuples
 # (source start file, target name, title, author,
 #  dir menu entry, description, category)
 texinfo_documents = [
-  ('index', 'transaction', u'transaction Documentation',
-   u'Zope Foundation Contributors', 'transaction', 'One line description of project.',
-   'Miscellaneous'),
+    ('index',
+     'transaction',
+     'transaction Documentation',
+     'Zope Foundation Contributors',
+     'transaction',
+     'One line description of project.',
+     'Miscellaneous'),
 ]
 
 # Documents to append as an appendix to all manuals.
-#texinfo_appendices = []
+# texinfo_appendices = []
 
 # If false, no module index is generated.
-#texinfo_domain_indices = True
+# texinfo_domain_indices = True
 
 # How to display URL addresses: 'footnote', 'no', or 'inline'.
-#texinfo_show_urls = 'footnote'
+# texinfo_show_urls = 'footnote'
 
 # Sphinx 1.8+ prefers this to `autodoc_default_flags`. It's documented that
 # either True or None mean the same thing as just setting the flag, but
diff --git a/pyproject.toml b/pyproject.toml
new file mode 100644
index 0000000..959c8ef
--- /dev/null
+++ b/pyproject.toml
@@ -0,0 +1,21 @@
+# 
+# Generated from:
+# https://github.com/zopefoundation/meta/tree/master/config/pure-python
+
+[build-system]
+requires = ["setuptools<74"]
+build-backend = "setuptools.build_meta"
+
+[tool.coverage.run]
+branch = true
+source = ["transaction"]
+
+[tool.coverage.report]
+fail_under = 99
+precision = 2
+ignore_errors = true
+show_missing = true
+exclude_lines = ["pragma: no cover", "pragma: nocover", "except ImportError:", "raise NotImplementedError", "if __name__ == '__main__':", "self.fail", "raise AssertionError", "raise unittest.Skip"]
+
+[tool.coverage.html]
+directory = "parts/htmlcov"
diff --git a/setup.cfg b/setup.cfg
index 306ffb2..a73efa3 100644
--- a/setup.cfg
+++ b/setup.cfg
@@ -1,7 +1,5 @@
 # Generated from:
 # https://github.com/zopefoundation/meta/tree/master/config/pure-python
-[bdist_wheel]
-universal = 0
 
 [flake8]
 doctests = 1
diff --git a/setup.py b/setup.py
index a105f06..6422a74 100644
--- a/setup.py
+++ b/setup.py
@@ -17,7 +17,7 @@
 from setuptools import setup
 
 
-version = '4.1.dev0'
+version = '5.0.dev0'
 here = os.path.abspath(os.path.dirname(__file__))
 
 
@@ -32,6 +32,7 @@ def _read_file(filename):
       version=version,
       description='Transaction management for Python',
       long_description=README,
+      long_description_content_type='text/x-rst',
       classifiers=[
           "Development Status :: 6 - Mature",
           "License :: OSI Approved :: Zope Public License",
@@ -42,12 +43,12 @@ def _read_file(filename):
           "Operating System :: Unix",
           "Programming Language :: Python",
           "Programming Language :: Python :: 3",
-          "Programming Language :: Python :: 3.7",
           "Programming Language :: Python :: 3.8",
           "Programming Language :: Python :: 3.9",
           "Programming Language :: Python :: 3.10",
           "Programming Language :: Python :: 3.11",
           "Programming Language :: Python :: 3.12",
+          "Programming Language :: Python :: 3.13",
           "Programming Language :: Python :: Implementation :: CPython",
           "Programming Language :: Python :: Implementation :: PyPy",
           "Framework :: ZODB",
@@ -66,7 +67,7 @@ def _read_file(filename):
       package_dir={'': 'src'},
       include_package_data=True,
       zip_safe=False,
-      python_requires='>=3.7',
+      python_requires='>=3.8',
       install_requires=[
           'zope.interface',
       ],
diff --git a/src/transaction/_compat.py b/src/transaction/_compat.py
deleted file mode 100644
index 757cb19..0000000
--- a/src/transaction/_compat.py
+++ /dev/null
@@ -1,10 +0,0 @@
-def text_(s):
-    if not isinstance(s, str):  # pragma: no cover
-        s = s.decode('utf-8')
-    return s
-
-
-def native_(s, encoding='latin-1', errors='strict'):
-    if isinstance(s, str):
-        return s
-    return str(s, encoding, errors)
diff --git a/src/transaction/_manager.py b/src/transaction/_manager.py
index d8c0aa8..8ca13f0 100644
--- a/src/transaction/_manager.py
+++ b/src/transaction/_manager.py
@@ -22,7 +22,6 @@
 
 from zope.interface import implementer
 
-from transaction._compat import text_
 from transaction._transaction import Transaction
 from transaction.interfaces import AlreadyInTransaction
 from transaction.interfaces import ITransactionManager
@@ -185,11 +184,13 @@ def run(self, func=None, tries=3):
         # These are ordinarily strings, but that's
         # not required. A callable class could override them
         # to anything.
-        name = func.__name__
-        doc = func.__doc__
+        name = func.__name__ or ''
+        doc = func.__doc__ or ''
 
-        name = text_(name) if name else ''
-        doc = text_(doc) if doc else ''
+        if isinstance(name, bytes):
+            name = name.decode('UTF-8')
+        if isinstance(doc, bytes):
+            doc = doc.decode('UTF-8')
 
         if name and name != '_':
             if doc:
diff --git a/src/transaction/_transaction.py b/src/transaction/_transaction.py
index 173f2be..2b3893f 100644
--- a/src/transaction/_transaction.py
+++ b/src/transaction/_transaction.py
@@ -583,7 +583,7 @@ def note(self, text):
 
     def setUser(self, user_name, path="/"):
         """See `~transaction.interfaces.ITransaction`."""
-        self.user = "{} {}".format(text_or_warn(path), text_or_warn(user_name))
+        self.user = f"{text_or_warn(path)} {text_or_warn(user_name)}"
 
     def setExtendedInfo(self, name, value):
         """See `~transaction.interfaces.ITransaction`."""
diff --git a/src/transaction/tests/examples.py b/src/transaction/tests/examples.py
index c25b28d..79a4fec 100644
--- a/src/transaction/tests/examples.py
+++ b/src/transaction/tests/examples.py
@@ -21,6 +21,7 @@ class DataManager:
 
     Used by the 'datamanager' chapter in the Sphinx docs.
     """
+
     def __init__(self):
         self.state = 0
         self.sp = 0
diff --git a/src/transaction/tests/test__manager.py b/src/transaction/tests/test__manager.py
index 0d6a183..2ae6cdc 100644
--- a/src/transaction/tests/test__manager.py
+++ b/src/transaction/tests/test__manager.py
@@ -42,14 +42,14 @@ def test_interface(self):
 
     def test_ctor(self):
         tm = self._makeOne()
-        self.assertTrue(tm._txn is None)
+        self.assertIsNone(tm._txn)
         self.assertEqual(len(tm._synchs), 0)
 
     def test_begin_wo_existing_txn_wo_synchs(self):
         from transaction._transaction import Transaction
         tm = self._makeOne()
         tm.begin()
-        self.assertTrue(isinstance(tm._txn, Transaction))
+        self.assertIsInstance(tm._txn, Transaction)
 
     def test_begin_wo_existing_txn_w_synchs(self):
         from transaction._transaction import Transaction
@@ -57,8 +57,8 @@ def test_begin_wo_existing_txn_w_synchs(self):
         synch = DummySynch()
         tm.registerSynch(synch)
         tm.begin()
-        self.assertTrue(isinstance(tm._txn, Transaction))
-        self.assertTrue(tm._txn in synch._txns)
+        self.assertIsInstance(tm._txn, Transaction)
+        self.assertIn(tm._txn, synch._txns)
 
     def test_begin_w_existing_txn(self):
         class Existing:
@@ -69,14 +69,14 @@ def abort(self):
         tm = self._makeOne()
         tm._txn = txn = Existing()
         tm.begin()
-        self.assertFalse(tm._txn is txn)
+        self.assertIsNot(tm._txn, txn)
         self.assertTrue(txn._aborted)
 
     def test_get_wo_existing_txn(self):
         from transaction._transaction import Transaction
         tm = self._makeOne()
         txn = tm.get()
-        self.assertTrue(isinstance(txn, Transaction))
+        self.assertIsInstance(txn, Transaction)
 
     def test_get_w_existing_txn(self):
         class Existing:
@@ -111,7 +111,7 @@ def test_registerSynch(self):
         synch = DummySynch()
         tm.registerSynch(synch)
         self.assertEqual(len(tm._synchs), 1)
-        self.assertTrue(synch in tm._synchs)
+        self.assertIn(synch, tm._synchs)
 
     def test_unregisterSynch(self):
         tm = self._makeOne()
@@ -125,8 +125,8 @@ def test_unregisterSynch(self):
         tm.unregisterSynch(synch1)
         self.assertTrue(tm.registeredSynchs())
         self.assertEqual(len(tm._synchs), 1)
-        self.assertFalse(synch1 in tm._synchs)
-        self.assertTrue(synch2 in tm._synchs)
+        self.assertNotIn(synch1, tm._synchs)
+        self.assertIn(synch2, tm._synchs)
         tm.unregisterSynch(synch2)
         self.assertFalse(tm.registeredSynchs())
 
@@ -255,7 +255,7 @@ def test_attempts_w_valid_count(self):
         tm = self._makeOne()
         found = list(tm.attempts(1))
         self.assertEqual(len(found), 1)
-        self.assertTrue(found[0] is tm)
+        self.assertIs(found[0], tm)
 
     def test_attempts_stop_on_success(self):
         tm = self._makeOne()
@@ -337,9 +337,9 @@ def test_attempts_w_default_count(self):
         found = list(tm.attempts())
         self.assertEqual(len(found), 3)
         for attempt in found[:-1]:
-            self.assertTrue(isinstance(attempt, Attempt))
-            self.assertTrue(attempt.manager is tm)
-        self.assertTrue(found[-1] is tm)
+            self.assertIsInstance(attempt, Attempt)
+            self.assertIs(attempt.manager, tm)
+        self.assertIs(found[-1], tm)
 
     def test_run(self):
         import transaction.interfaces
@@ -880,7 +880,7 @@ def test_explicit_mode(self):
         with self.assertRaises(AlreadyInTransaction):
             tm.begin()
 
-        self.assertTrue(t is tm.get())
+        self.assertIs(t, tm.get())
 
         self.assertFalse(tm.isDoomed())
         tm.doom()
@@ -973,7 +973,7 @@ def sortKey(self):
 
     def check(self, method):
         if self.tracing:  # pragma: no cover
-            print('{} calling method {}'.format(str(self.tracing), method))
+            print(f'{str(self.tracing)} calling method {method}')
 
         if method in self.errors:
             raise TestTxnException("error %s" % method)
diff --git a/src/transaction/tests/test__transaction.py b/src/transaction/tests/test__transaction.py
index 4f1258c..ffb19b3 100644
--- a/src/transaction/tests/test__transaction.py
+++ b/src/transaction/tests/test__transaction.py
@@ -70,23 +70,23 @@ def test_ctor_defaults(self):
         logger = DummyLogger()
         with Monkey(_transaction, _LOGGER=logger):
             txn = self._makeOne()
-        self.assertTrue(isinstance(txn._synchronizers, WeakSet))
+        self.assertIsInstance(txn._synchronizers, WeakSet)
         self.assertEqual(len(txn._synchronizers), 0)
-        self.assertTrue(txn._manager is None)
+        self.assertIsNone(txn._manager)
         self.assertEqual(txn.user, "")
         self.assertEqual(txn.description, "")
-        self.assertTrue(txn._savepoint2index is None)
+        self.assertIsNone(txn._savepoint2index)
         self.assertEqual(txn._savepoint_index, 0)
         self.assertEqual(txn._resources, [])
         self.assertEqual(txn._adapters, {})
         self.assertEqual(txn._voted, {})
         self.assertEqual(txn.extension, {})
-        self.assertTrue(txn._extension is txn.extension)  # legacy
-        self.assertTrue(txn.log is logger)
+        self.assertIs(txn._extension, txn.extension)  # legacy
+        self.assertIs(txn.log, logger)
         self.assertEqual(len(logger._log), 1)
         self.assertEqual(logger._log[0][0], 'debug')
         self.assertEqual(logger._log[0][1], 'new transaction')
-        self.assertTrue(txn._failure_traceback is None)
+        self.assertIsNone(txn._failure_traceback)
         self.assertEqual(txn._before_commit, [])
         self.assertEqual(txn._after_commit, [])
 
@@ -94,7 +94,7 @@ def test_ctor_w_syncs(self):
         from transaction.weakset import WeakSet
         synchs = WeakSet()
         txn = self._makeOne(synchronizers=synchs)
-        self.assertTrue(txn._synchronizers is synchs)
+        self.assertIs(txn._synchronizers, synchs)
 
     def test_isDoomed(self):
         from transaction._transaction import Status
@@ -205,11 +205,11 @@ def test_savepoint_empty(self):
         with Monkey(_transaction, _LOGGER=logger):
             txn = self._makeOne()
         sp = txn.savepoint()
-        self.assertTrue(isinstance(sp, Savepoint))
-        self.assertTrue(sp.transaction is txn)
+        self.assertIsInstance(sp, Savepoint)
+        self.assertIs(sp.transaction, txn)
         self.assertEqual(sp._savepoints, [])
         self.assertEqual(txn._savepoint_index, 1)
-        self.assertTrue(isinstance(txn._savepoint2index, WeakKeyDictionary))
+        self.assertIsInstance(txn._savepoint2index, WeakKeyDictionary)
         self.assertEqual(txn._savepoint2index[sp], 1)
 
     def test_savepoint_non_optimistc_resource_wo_support(self):
@@ -227,8 +227,8 @@ def test_savepoint_non_optimistc_resource_wo_support(self):
         txn._resources.append(resource)
         self.assertRaises(TypeError, txn.savepoint)
         self.assertEqual(txn.status, Status.COMMITFAILED)
-        self.assertTrue(isinstance(txn._failure_traceback, StringIO))
-        self.assertTrue('TypeError' in txn._failure_traceback.getvalue())
+        self.assertIsInstance(txn._failure_traceback, StringIO)
+        self.assertIn('TypeError', txn._failure_traceback.getvalue())
         self.assertEqual(len(logger._log), 2)
         self.assertEqual(logger._log[0][0], 'error')
         self.assertTrue(logger._log[0][1].startswith('Error in abort'))
@@ -336,7 +336,7 @@ def free(self, txn):
             mgr = txn._manager = _Mgr(txn)
             txn.commit()
         self.assertEqual(txn.status, Status.COMMITTED)
-        self.assertTrue(mgr._txn is None)
+        self.assertIsNone(mgr._txn)
         self.assertEqual(logger._log[0][0], 'debug')
         self.assertEqual(logger._log[0][1], 'commit')
 
@@ -413,8 +413,8 @@ def afterCompletion(self, txn):
             logger._clear()
             txn.commit()
         for synch in synchs:
-            self.assertTrue(synch._before is txn)
-            self.assertTrue(synch._after is txn)
+            self.assertIs(synch._before, txn)
+            self.assertIs(synch._after, txn)
 
     def test_commit_w_afterCommitHooks(self):
         from transaction import _transaction
@@ -511,8 +511,8 @@ def tpc_begin(self, txn):
             txn._resources.append(broken)
             self.assertRaises(ValueError, txn.commit)
         for synch in synchs:
-            self.assertTrue(synch._before is txn)
-            self.assertTrue(synch._after is txn)  # called in _cleanup
+            self.assertIs(synch._before, txn)
+            self.assertIs(synch._after, txn)  # called in _cleanup
 
     def test_commit_clears_resources(self):
         class DM:
@@ -650,7 +650,7 @@ def test__commitResources_normal(self):
         for r in resources:
             self.assertTrue(r._b and r._c and r._v and r._f)
             self.assertFalse(r._a and r._x)
-            self.assertTrue(id(r) in txn._voted)
+            self.assertIn(id(r), txn._voted)
         self.assertEqual(len(logger._log), 2)
         self.assertEqual(logger._log[0][0], 'debug')
         self.assertEqual(logger._log[0][1], 'commit Resource: aaa')
@@ -747,13 +747,13 @@ def test__commitResources_error_in_tpc_vote(self):
         for r in resources:
             self.assertTrue(r._b and r._c)
             if r._key == 'aaa':
-                self.assertTrue(id(r) in txn._voted)
+                self.assertIn(id(r), txn._voted)
                 self.assertTrue(r._v)
                 self.assertFalse(r._f)
                 self.assertFalse(r._a)
                 self.assertTrue(r._x)
             else:
-                self.assertFalse(id(r) in txn._voted)
+                self.assertNotIn(id(r), txn._voted)
                 self.assertFalse(r._v)
                 self.assertFalse(r._f)
                 self.assertTrue(r._a and r._x)
@@ -776,7 +776,7 @@ def test__commitResources_error_in_tpc_finish(self):
         self.assertRaises(ValueError, txn._commitResources)
         for r in resources:
             self.assertTrue(r._b and r._c and r._v)
-            self.assertTrue(id(r) in txn._voted)
+            self.assertIn(id(r), txn._voted)
             if r._key == 'aaa':
                 self.assertTrue(r._f)
             else:
@@ -811,7 +811,7 @@ def free(self, txn):
             mgr = txn._manager = _Mgr(txn)
             txn.abort()
         self.assertEqual(txn.status, Status.ACTIVE)
-        self.assertTrue(mgr._txn is None)
+        self.assertIsNone(mgr._txn)
         self.assertEqual(logger._log[0][0], 'debug')
         self.assertEqual(logger._log[0][1], 'abort')
 
@@ -1026,8 +1026,8 @@ def abort(self, txn):
             t._resources.append(broken)
             self.assertRaises(ValueError, t.abort)
         for synch in synchs:
-            self.assertTrue(synch._before is t)
-            self.assertTrue(synch._after is t)  # called in _cleanup
+            self.assertIs(synch._before, t)
+            self.assertIs(synch._after, t)  # called in _cleanup
         self.assertIsNot(t._synchronizers, ws)
 
     def test_abort_synchronizer_error_w_resources(self):
@@ -1068,8 +1068,8 @@ def map(self, func):
                 t.abort()
 
         for synch in synchs.synchs:
-            self.assertTrue(synch._before is t)
-            self.assertTrue(synch._after is t)  # called in _cleanup
+            self.assertIs(synch._before, t)
+            self.assertIs(synch._after, t)  # called in _cleanup
         self.assertIsNot(t._synchronizers, synchs)
         self.assertTrue(resource._a)
 
@@ -1389,7 +1389,7 @@ def test_setExtendedInfo_single(self):
         txn = self._makeOne()
         txn.setExtendedInfo('frob', 'qux')
         self.assertEqual(txn.extension, {'frob': 'qux'})
-        self.assertTrue(txn._extension is txn._extension)  # legacy
+        self.assertIs(txn._extension, txn._extension)  # legacy
 
     def test_setExtendedInfo_multiple(self):
         txn = self._makeOne()
@@ -1397,7 +1397,7 @@ def test_setExtendedInfo_multiple(self):
         txn.setExtendedInfo('baz', 'spam')
         txn.setExtendedInfo('frob', 'quxxxx')
         self.assertEqual(txn._extension, {'frob': 'quxxxx', 'baz': 'spam'})
-        self.assertTrue(txn._extension is txn._extension)  # legacy
+        self.assertIs(txn._extension, txn._extension)  # legacy
 
     def test__extension_settable(self):
         # Because ZEO sets it. I'll fix ZEO, but maybe something else will
@@ -1489,7 +1489,7 @@ def _callFUT(self, oid):
         return rm_key(oid)
 
     def test_miss(self):
-        self.assertTrue(self._callFUT(object()) is None)
+        self.assertIsNone(self._callFUT(object()))
 
     def test_hit(self):
         self.assertEqual(self._callFUT(Resource('zzz')), 'zzz')
@@ -1515,8 +1515,8 @@ def test_ctor_w_savepoint_oblivious_resource_optimistic(self):
         resource = object()
         sp = self._makeOne(txn, True, resource)
         self.assertEqual(len(sp._savepoints), 1)
-        self.assertTrue(isinstance(sp._savepoints[0], NoRollbackSavepoint))
-        self.assertTrue(sp._savepoints[0].datamanager is resource)
+        self.assertIsInstance(sp._savepoints[0], NoRollbackSavepoint)
+        self.assertIs(sp._savepoints[0].datamanager, resource)
 
     def test_ctor_w_savepoint_aware_resources(self):
         class _Aware:
@@ -1527,10 +1527,10 @@ def savepoint(self):
         another = _Aware()
         sp = self._makeOne(txn, True, one, another)
         self.assertEqual(len(sp._savepoints), 2)
-        self.assertTrue(isinstance(sp._savepoints[0], _Aware))
-        self.assertTrue(sp._savepoints[0] is one)
-        self.assertTrue(isinstance(sp._savepoints[1], _Aware))
-        self.assertTrue(sp._savepoints[1] is another)
+        self.assertIsInstance(sp._savepoints[0], _Aware)
+        self.assertIs(sp._savepoints[0], one)
+        self.assertIsInstance(sp._savepoints[1], _Aware)
+        self.assertIs(sp._savepoints[1], another)
 
     def test_valid_wo_transacction(self):
         sp = self._makeOne(None, True, object())
@@ -1578,7 +1578,7 @@ def savepoint(self):
         resource = _GonnaRaise()
         sp = self._makeOne(txn, False, resource)
         self.assertRaises(ValueError, sp.rollback)
-        self.assertTrue(txn._raia is sp)
+        self.assertIs(txn._raia, sp)
         self.assertTrue(txn._sarce)
 
 
@@ -1595,8 +1595,8 @@ def test_ctor(self):
         dm = object()
         txn = object()
         asp = self._makeOne(dm, txn)
-        self.assertTrue(asp.datamanager is dm)
-        self.assertTrue(asp.transaction is txn)
+        self.assertIs(asp.datamanager, dm)
+        self.assertIs(asp.transaction, txn)
 
     def test_rollback(self):
         class _DM:
@@ -1614,8 +1614,8 @@ def _unjoin(self, datamanager):
         txn = _TXN()
         asp = self._makeOne(dm, txn)
         asp.rollback()
-        self.assertTrue(dm._aborted is txn)
-        self.assertTrue(txn._unjoin is dm)
+        self.assertIs(dm._aborted, txn)
+        self.assertIs(txn._unjoin, dm)
 
 
 class NoRollbackSavepointTests(unittest.TestCase):
@@ -1630,7 +1630,7 @@ def _makeOne(self, datamanager):
     def test_ctor(self):
         dm = object()
         nrsp = self._makeOne(dm)
-        self.assertTrue(nrsp.datamanager is dm)
+        self.assertIs(nrsp.datamanager, dm)
 
     def test_rollback(self):
         dm = object()
@@ -1697,7 +1697,6 @@ def _3():
 
     def test_gh5(self):
         from transaction import _transaction
-        from transaction._compat import native_
 
         buffer = _transaction._makeTracebackBuffer()
 
@@ -1705,7 +1704,7 @@ def test_gh5(self):
         buffer.write(s)
 
         buffer.seek(0)
-        self.assertEqual(buffer.read(), native_(s, 'utf-8'))
+        self.assertEqual(buffer.read(), s)
 
 
 class Resource:
diff --git a/src/transaction/tests/test_savepoint.py b/src/transaction/tests/test_savepoint.py
index 1b4d9f4..f7f0de2 100644
--- a/src/transaction/tests/test_savepoint.py
+++ b/src/transaction/tests/test_savepoint.py
@@ -31,17 +31,17 @@ def testRollbackRollsbackDataManagersThatJoinedLater(self):
         dm2 = savepointsample.SampleSavepointDataManager()
         dm2['name'] = 'sally'
 
-        self.assertTrue('name' in dm)
-        self.assertTrue('job' in dm)
-        self.assertTrue('salary' in dm)
-        self.assertTrue('name' in dm2)
+        self.assertIn('name', dm)
+        self.assertIn('job', dm)
+        self.assertIn('salary', dm)
+        self.assertIn('name', dm2)
 
         sp1.rollback()
 
-        self.assertTrue('name' in dm)
-        self.assertFalse('job' in dm)
-        self.assertFalse('salary' in dm)
-        self.assertFalse('name' in dm2)
+        self.assertIn('name', dm)
+        self.assertNotIn('job', dm)
+        self.assertNotIn('salary', dm)
+        self.assertNotIn('name', dm2)
 
     def test_commit_after_rollback_for_dm_that_joins_after_savepoint(self):
         # There was a problem handling data managers that joined after a
diff --git a/src/transaction/tests/test_weakset.py b/src/transaction/tests/test_weakset.py
index ad32dea..2700e03 100644
--- a/src/transaction/tests/test_weakset.py
+++ b/src/transaction/tests/test_weakset.py
@@ -79,7 +79,7 @@ def test_as_weakref_list(self):
         del dummy3
         gc.collect()
         refs = w.as_weakref_list()
-        self.assertTrue(isinstance(refs, list))
+        self.assertIsInstance(refs, list)
         L = [x() for x in refs]
         # L is a list, but it does not have a guaranteed order.
         self.assertTrue(list, type(L))
diff --git a/tox.ini b/tox.ini
index d50444f..b01282e 100644
--- a/tox.ini
+++ b/tox.ini
@@ -5,7 +5,6 @@ minversion = 3.18
 envlist =
     release-check
     lint
-    py37
     py38
     py39
     py310
@@ -20,53 +19,50 @@ envlist =
 usedevelop = true
 package = wheel
 wheel_build_env = .pkg
-pip_pre = py313: true
 deps =
+    setuptools  <74
     zope.testrunner
-    Sphinx
 setenv =
-    py312: VIRTUALENV_PIP=23.1.2
-    py312: PIP_REQUIRE_VIRTUALENV=0
 commands =
     zope-testrunner --test-path=src {posargs:-vc}
     sphinx-build -b doctest -d {envdir}/.cache/doctrees docs {envdir}/.cache/doctest
 extras =
     test
     docs
+
+[testenv:setuptools-latest]
+basepython = python3
+deps =
+    git+https://github.com/pypa/setuptools.git\#egg=setuptools
+    zope.testrunner
+
 [testenv:release-check]
 description = ensure that the distribution is ready to release
 basepython = python3
 skip_install = true
 deps =
+    setuptools <74
     twine
     build
     check-manifest
     check-python-versions >= 0.20.0
     wheel
+commands_pre =
 commands =
     check-manifest
-    check-python-versions
+    check-python-versions --only setup.py,tox.ini,.github/workflows/tests.yml
     python -m build --sdist --no-isolation
     twine check dist/*
 
 [testenv:lint]
+description = This env runs all linters configured in .pre-commit-config.yaml
 basepython = python3
 skip_install = true
 deps =
-    isort
-    flake8
-commands =
-    isort --check-only --diff {toxinidir}/src {toxinidir}/setup.py
-    flake8 src setup.py
-
-[testenv:isort-apply]
-basepython = python3
-skip_install = true
+    pre-commit
 commands_pre =
-deps =
-    isort
 commands =
-    isort {toxinidir}/src {toxinidir}/setup.py []
+    pre-commit run --all-files --show-diff-on-failure
 
 [testenv:docs]
 basepython = python3
@@ -81,30 +77,11 @@ basepython = python3
 allowlist_externals =
     mkdir
 deps =
-    coverage
+    coverage[toml]
     zope.testrunner
-    Sphinx
 commands =
     mkdir -p {toxinidir}/parts/htmlcov
     coverage run -m zope.testrunner --test-path=src {posargs:-vc}
     coverage run -a -m sphinx -b doctest -d {envdir}/.cache/doctrees docs {envdir}/.cache/doctest
-    coverage html --ignore-errors
-    coverage report --ignore-errors --show-missing --fail-under=99
-
-[coverage:run]
-branch = True
-source = transaction
-
-[coverage:report]
-precision = 2
-exclude_lines =
-    pragma: no cover
-    pragma: nocover
-    except ImportError:
-    raise NotImplementedError
-    if __name__ == '__main__':
-    self.fail
-    raise AssertionError
-
-[coverage:html]
-directory = parts/htmlcov
+    coverage html
+    coverage report