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@pauljohanneskraft
pauljohanneskraft committed Jun 17, 2024
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Expand Up @@ -28,14 +28,13 @@ A LocalizedText object cannot be used in FHIR-conforming types due to its incomp
}
```


## /questionnaires

In this section, we describe all the information stored for questionnaires.

### /questionnaires/$questionnaireId$

Based on [FHIR Questionnaire](https://hl7.org/fhir/R4B/questionnaire.html):
Based on [FHIR Questionnaire](https://hl7.org/fhir/R4B/questionnaire.html), the following properties may be used, while additional properties are ignored by the Engage-HF system.

|Property|Type|Values|Comments|
|-|-|-|-|
Expand All @@ -61,7 +60,7 @@ In this section, we describe information regarding all the medications to be spe

### /medications/$medicationId$

Based on [FHIR Medication](https://hl7.org/fhir/R4B/medication.html):
Based on [FHIR Medication](https://hl7.org/fhir/R4B/medication.html), the following properties may be used, while additional properties are ignored by the Engage-HF system.

|Property|Type|Values|Comments|
|-|-|-|-|
Expand Down Expand Up @@ -201,17 +200,175 @@ Q: Which codes should we use for contra-indications? We could simply assume a li

#### Relevant codes

TBD: We need to define a list of relevant codes for each medication class and medication to be used as input by clinicians and further be checked by the algorithm(s). Whenever we interface with an EHR, we will need to add checks for parents/children of the given codes to make sure, we do not ignore a given contra-indication, even though it is input correctly.
Here we keep a list of relevant codes for medication classes & medications for use in /medications, /medicationClasses and /users/$userId$/allergyIntolerances/$allergyIntoleranceId$.

Medication classes:
##### Medication classes

|Medication Class|Code|
|Medication class|SNOMED CT name|code|
|-|-|
|Beta blocker|Substance with beta adrenergic receptor antagonist mechanism of action (substance)|[373254001](https://browser.ihtsdotools.org/?perspective=full&conceptId1=373254001)|
|SGLT2i|Substance with sodium glucose cotransporter subtype 2 inhibitor mechanism of action (substance)|[703673007](https://browser.ihtsdotools.org/?perspective=full&conceptId1=703673007)|
|MRA|Substance with aldosterone receptor antagonist mechanism of action (substance)|[372603003](https://browser.ihtsdotools.org/?perspective=full&conceptId1=372603003)|
|ACEI|Substance with angiotensin-converting enzyme inhibitor mechanism of action (substance)|[372733002](https://browser.ihtsdotools.org/?perspective=full&conceptId1=372733002)|
|ARB|Substance with renin-angiotensin system inhibitor mechanism of action (substance)|[866173006](https://browser.ihtsdotools.org/?perspective=full&conceptId1=866173006)|
|ARNI|Substance with neprilysin inhibitor mechanism of action (substance)|[786886009](https://browser.ihtsdotools.org/?perspective=full&conceptId1=786886009)|
|Diuretics|Diuretic (substance)|[372695000](https://browser.ihtsdotools.org/?perspective=full&conceptId1=372695000)|

Medications:
###### Medications & Doses

|Medication|Code|Alternative|
|Medication|Dose|Code|
|-|-|-|
|Metoprolol succinate|-|[412432007](https://browser.ihtsdotools.org/?perspective=full&conceptId1=412432007)|
|Metoprolol succinate ER|25mg|[879978003](https://browser.ihtsdotools.org/?perspective=full&conceptId1=879978003)|
|Metoprolol succinate ER|50mg|[879979006](https://browser.ihtsdotools.org/?perspective=full&conceptId1=879979006)|
|Metoprolol succinate ER|100mg|[879980009](https://browser.ihtsdotools.org/?perspective=full&conceptId1=879980009)|
|Metoprolol succinate ER|200mg|[879981008](https://browser.ihtsdotools.org/?perspective=full&conceptId1=879981008)|
|Carvedilol|-|[386870007](https://browser.ihtsdotools.org/?perspective=full&conceptId1=386870007)|
|Carvedilol|3.125mg|[318633000](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318633000)|
|Carvedilol|6.25mg|[318635007](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318635007)|
|Carvedilol|12.5mg|[318631003](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318631003)|
|Carvedilol|25mg|[318632005](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318632005)|
|Carvedilol phosphate|-|[426471008](https://browser.ihtsdotools.org/?perspective=full&conceptId1=426471008)|
|Carvedilol phosphate ER|10mg|[1187445001](https://browser.ihtsdotools.org/?perspective=full&conceptId1=1187445001)|
|Carvedilol phosphate ER|20mg|[1187446000](https://browser.ihtsdotools.org/?perspective=full&conceptId1=1187446000)|
|Carvedilol phosphate ER|40mg|[1208576006](https://browser.ihtsdotools.org/?perspective=full&conceptId1=1208576006)|
|Carvedilol phosphate ER|80mg|[1208577002](https://browser.ihtsdotools.org/?perspective=full&conceptId1=1208577002)|
|Bisoprolol|-|[386868003](https://browser.ihtsdotools.org/?perspective=full&conceptId1=386868003)|
|Bisoprolol|5mg|[318590006](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318590006)|
|Bisoprolol|10mg|[318591005](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318591005)|
|Dapagliflozin|-|[703674001](https://browser.ihtsdotools.org/?perspective=full&conceptId1=703674001)|
|Dapagliflozin|10mg|[1145541007](https://browser.ihtsdotools.org/?perspective=full&conceptId1=1145541007)|
|Empagliflozin|-|[703894008](https://browser.ihtsdotools.org/?perspective=full&conceptId1=703894008)|
|Empagliflozin|10mg|[703896005](https://browser.ihtsdotools.org/?perspective=full&conceptId1=703896005)|
|Empagliflozin|25mg|[703897001](https://browser.ihtsdotools.org/?perspective=full&conceptId1=703897001)|
|Sotagliflozin|-|TBD|
|Sotagliflozin|200mg|TBD|
|Sotagliflozin|400mg|TBD|
|Bexagliflozin|-|TBD|
|Bexagliflozin|20mg|TBD|
|Canagliflozin|-|[703676004](https://browser.ihtsdotools.org/?perspective=full&conceptId1=703676004)|
|Canagliflozin|100mg|[703682001](https://browser.ihtsdotools.org/?perspective=full&conceptId1=703682001)|
|Canagliflozin|300mg|[765627002](https://browser.ihtsdotools.org/?perspective=full&conceptId1=765627002)|
|Ertugliflozin|-|[764274008](https://browser.ihtsdotools.org/?perspective=full&conceptId1=764274008)|
|Ertugliflozin|5mg|[1162397007](https://browser.ihtsdotools.org/?perspective=full&conceptId1=1162397007)|
|Ertugliflozin|15mg|[1162394000](https://browser.ihtsdotools.org/?perspective=full&conceptId1=1162394000)|
|Spironolactone|-|[387078006](https://browser.ihtsdotools.org/?perspective=full&conceptId1=387078006)|
|Spironolactone|25mg|[318056008](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318056008)|
|Spironolactone|50mg|[318057004](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318057004)|
|Spironolactone|100mg|[318058009](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318058009)|
|Eplerenone|-|[407010008](https://browser.ihtsdotools.org/?perspective=full&conceptId1=407010008)|
|Eplerenone|25mg|[407011007](https://browser.ihtsdotools.org/?perspective=full&conceptId1=407011007)|
|Eplerenone|50mg|[407012000](https://browser.ihtsdotools.org/?perspective=full&conceptId1=407012000)|
|Quinapril|-|[386874003](https://browser.ihtsdotools.org/?perspective=full&conceptId1=386874003)|
|Quinapril|5mg|[318885001](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318885001)|
|Quinapril|10mg|[318886000](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318886000)|
|Quinapril|20mg|[318887009](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318887009)|
|Quinapril|40mg|[318894007](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318894007)|
|Perindopril|-|[372916001](https://browser.ihtsdotools.org/?perspective=full&conceptId1=372916001)|
|Perindopril|2mg|[318896009](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318896009)|
|Perindopril|4mg|[318897000](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318897000)|
|Perindopril|8mg|[374667004](https://browser.ihtsdotools.org/?perspective=full&conceptId1=374667004)|
|Ramipril|-|[386872004](https://browser.ihtsdotools.org/?perspective=full&conceptId1=386872004)|
|Ramipril|1.25mg|tablet: [408040007](https://browser.ihtsdotools.org/?perspective=full&conceptId1=408040007), capsule: [318900007](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318900007)|
|Ramipril|2.5mg|tablet: [408050008](https://browser.ihtsdotools.org/?perspective=full&conceptId1=408050008), capsule: [318901006](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318901006)|
|Ramipril|5mg|tablet: [408051007](https://browser.ihtsdotools.org/?perspective=full&conceptId1=408051007), capsule: [318902004](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318902004)|
|Ramipril|10mg|tablet: [408052000](https://browser.ihtsdotools.org/?perspective=full&conceptId1=408052000), capsule: [318906001](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318906001)|
|Benazepril|-|[372511001](https://browser.ihtsdotools.org/?perspective=full&conceptId1=372511001)|
|Benazepril|5mg|[376516008](https://browser.ihtsdotools.org/?perspective=full&conceptId1=376516008)|
|Benazepril|10mg|[376518009](https://browser.ihtsdotools.org/?perspective=full&conceptId1=376518009)|
|Benazepril|20mg|[376520007](https://browser.ihtsdotools.org/?perspective=full&conceptId1=376520007)|
|Benazepril|40mg|[376521006](https://browser.ihtsdotools.org/?perspective=full&conceptId1=376521006)|
|Captopril|-|[387160004](https://browser.ihtsdotools.org/?perspective=full&conceptId1=387160004)|
|Captopril|12.5mg|[318820009](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318820009)|
|Captopril|25mg|[318821008](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318821008)|
|Captopril|50mg|[318824000](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318824000)|
|Captopril|100mg|[375105000](https://browser.ihtsdotools.org/?perspective=full&conceptId1=375105000)|
|Enalapril|-|[372658000](https://browser.ihtsdotools.org/?perspective=full&conceptId1=372658000)|
|Enalapril|2.5mg|[318850001](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318850001)|
|Enalapril|5mg|[318851002](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318851002)|
|Enalapril|10mg|[318853004](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318853004)|
|Enalapril|20mg|[318855006](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318855006)|
|Lisinopril|-|[386873009](https://browser.ihtsdotools.org/?perspective=full&conceptId1=386873009)|
|Lisinopril|2.5mg|[318857003](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318857003)|
|Lisinopril|5mg|[318858008](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318858008)|
|Lisinopril|10mg|[318859000](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318859000)|
|Lisinopril|20mg|[318860005](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318860005)|
|Lisinopril|30mg|[374040006](https://browser.ihtsdotools.org/?perspective=full&conceptId1=374040006)|
|Lisinopril|40mg|[376772000](https://browser.ihtsdotools.org/?perspective=full&conceptId1=376772000)|
|Fosinopril|-|[372510000](https://browser.ihtsdotools.org/?perspective=full&conceptId1=372510000), sodium: [108570006](https://browser.ihtsdotools.org/?perspective=full&conceptId1=108570006)|
|Fosinopril|10mg|sodium: [318909008](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318909008)|
|Fosinopril|20mg|sodium: [318910003](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318910003)|
|Fosinopril|40mg|sodium: [376699008](https://browser.ihtsdotools.org/?perspective=full&conceptId1=376699008)|
|Trandolapril|-|[386871006](https://browser.ihtsdotools.org/?perspective=full&conceptId1=386871006)|
|Trandolapril|1mg|[375094007](https://browser.ihtsdotools.org/?perspective=full&conceptId1=375094007)|
|Trandolapril|2mg|[375095008](https://browser.ihtsdotools.org/?perspective=full&conceptId1=375095008)|
|Trandolapril|4mg|[375096009](https://browser.ihtsdotools.org/?perspective=full&conceptId1=375096009)|
|Moexipril|-|[373442003](https://browser.ihtsdotools.org/?perspective=full&conceptId1=373442003)|
|Moexipril|7.5mg|[318934008](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318934008)|
|Moexipril|15mg|[318935009](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318935009)|
|Losartan|-|[373567002](https://browser.ihtsdotools.org/?perspective=full&conceptId1=373567002), potassium: [108582002](https://browser.ihtsdotools.org/?perspective=full&conceptId1=108582002)|
|Losartan|25mg|potassium: [318955005](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318955005)|
|Losartan|50mg|potassium: [318956006](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318956006)|
|Losartan|100mg|potassium: [407784004](https://browser.ihtsdotools.org/?perspective=full&conceptId1=407784004)|
|Valsartan|-|[386876001](https://browser.ihtsdotools.org/?perspective=full&conceptId1=386876001)|
|Valsartan|40mg|[416515008](https://browser.ihtsdotools.org/?perspective=full&conceptId1=416515008)|
|Valsartan|80mg|[375034009](https://browser.ihtsdotools.org/?perspective=full&conceptId1=375034009)|
|Valsartan|160mg|[375035005](https://browser.ihtsdotools.org/?perspective=full&conceptId1=375035005)|
|Valsartan|320mg|[376487009](https://browser.ihtsdotools.org/?perspective=full&conceptId1=376487009)|
|Candesartan|-|[372512008](https://browser.ihtsdotools.org/?perspective=full&conceptId1=372512008)|
|Candesartan|2mg|cilexetil: [318977009](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318977009)|
|Candesartan|4mg|cilexetil: [318978004](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318978004)|
|Candesartan|8mg|cilexetil: [318979007](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318979007)|
|Candesartan|16mg|cilexetil: [318980005](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318980005)|
|Candesartan|32mg|cilexetil: [376998003](https://browser.ihtsdotools.org/?perspective=full&conceptId1=376998003)|
|Irbesartan|-|[386877005](https://browser.ihtsdotools.org/?perspective=full&conceptId1=386877005)|
|Irbesartan|75mg|[318968002](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318968002)|
|Irbesartan|150mg|[318969005](https://browser.ihtsdotools.org/?perspective=full&conceptId1318969005)|
|Irbesartan|300mg|[318970006](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318970006)|
|Telmisartan|-|[387069000](https://browser.ihtsdotools.org/?perspective=full&conceptId1=387069000)|
|Telmisartan|20mg|[134463001](https://browser.ihtsdotools.org/?perspective=full&conceptId1=134463001)|
|Telmisartan|40mg|[318986004](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318986004)|
|Telmisartan|80mg|[318987008](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318987008)|
|Olmesartan|-|[412259001](https://browser.ihtsdotools.org/?perspective=full&conceptId1=412259001), medoxomil: [412260006](https://browser.ihtsdotools.org/?perspective=full&conceptId1=412260006)|
|Olmesartan|5mg|medoxomil: [385541002](https://browser.ihtsdotools.org/?perspective=full&conceptId1=385541002)|
|Olmesartan|10mg|medoxomil: [408055003](https://browser.ihtsdotools.org/?perspective=full&conceptId1=408055003)|
|Olmesartan|20mg|medoxomil: [385542009](https://browser.ihtsdotools.org/?perspective=full&conceptId1=385542009)|
|Olmesartan|40mg|medoxomil: [385543004](https://browser.ihtsdotools.org/?perspective=full&conceptId1=385543004)|
|Azilsartan|-|[385542009](https://browser.ihtsdotools.org/?perspective=full&conceptId1=385542009), medoxomil: [449561004](https://browser.ihtsdotools.org/?perspective=full&conceptId1=449561004)|
|Azilsartan|20mg|medoxomil: [895430006](https://browser.ihtsdotools.org/?perspective=full&conceptId1=895430006)|
|Azilsartan|40mg|medoxomil: [1137333005](https://browser.ihtsdotools.org/?perspective=full&conceptId1=1137333005)|
|Azilsartan|80mg|medoxomil: [1137623008](https://browser.ihtsdotools.org/?perspective=full&conceptId1=1137623008)|
|Eprosartan|-|[396044005](https://browser.ihtsdotools.org/?perspective=full&conceptId1=396044005), mesilate: [129488003](https://browser.ihtsdotools.org/?perspective=full&conceptId1=129488003)|
|Eprosartan|300mg|mesilate: [318994006](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318994006)|
|Eprosartan|400mg|mesilate: [318995007](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318995007)|
|Eprosartan|600mg|mesilate: [318996008](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318995007)|
|Eprosartan|800mg|TBD|
|Sacubitril- Valsartan|-|[777480008](https://browser.ihtsdotools.org/?perspective=full&conceptId1=777480008)|
|Sacubitril- Valsartan|24-26mg|[1162681006](https://browser.ihtsdotools.org/?perspective=full&conceptId1=1162681006)|
|Sacubitril- Valsartan|49-51mg|[1162682004](https://browser.ihtsdotools.org/?perspective=full&conceptId1=1162682004)|
|Sacubitril- Valsartan|97-103mg|[1162718004](https://browser.ihtsdotools.org/?perspective=full&conceptId1=1162718004)|
|Furosemide|-|[387475002](https://browser.ihtsdotools.org/?perspective=full&conceptId1=387475002)|
|Furosemide|20mg|[317971007](https://browser.ihtsdotools.org/?perspective=full&conceptId1=317971007)|
|Furosemide|40mg|[317972000](https://browser.ihtsdotools.org/?perspective=full&conceptId1=317972000)|
|Furosemide|80mg|[395510001](https://browser.ihtsdotools.org/?perspective=full&conceptId1=395510001)|
|Furosemide|100mg|[1187430008](https://browser.ihtsdotools.org/?perspective=full&conceptId1=1187430008)|
|Furosemide|500mg|[317973005](https://browser.ihtsdotools.org/?perspective=full&conceptId1=317973005)|
|Bumetanide|-|[387498005](https://browser.ihtsdotools.org/?perspective=full&conceptId1=387498005)|
|Bumetanide|0.5mg|[375553009](https://browser.ihtsdotools.org/?perspective=full&conceptId1=375553009)|
|Bumetanide|1mg|[318021009](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318021009)|
|Bumetanide|2mg|[375648005](https://browser.ihtsdotools.org/?perspective=full&conceptId1=375648005)|
|Bumetanide|5mg|[318022002](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318022002)|
|Torsemide|-|[108476002](https://browser.ihtsdotools.org/?perspective=full&conceptId1=108476002)|
|Torsemide|2.5mg|[318040003](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318040003)|
|Torsemide|5mg|[318041004](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318041004)|
|Torsemide|10mg|[318042006](https://browser.ihtsdotools.org/?perspective=full&conceptId1=318042006)|
|Torsemide|20mg|[375711005](https://browser.ihtsdotools.org/?perspective=full&conceptId1=375711005)|
|Torsemide|40mg|TBD|
|Torsemide|60mg|TBD|
|Torsemide|100mg|[375714002](https://browser.ihtsdotools.org/?perspective=full&conceptId1=375714002)|
|Ethacrynic Acid|-|[373536004](https://browser.ihtsdotools.org/?perspective=full&conceptId1=373536004)|
|Ethacrynic Acid|25mg|[376668007](https://browser.ihtsdotools.org/?perspective=full&conceptId1=376668007)|
|Ethacrynic Acid|50mg|[376679002](https://browser.ihtsdotools.org/?perspective=full&conceptId1=376679002)|

### /users/$userId$/medicationRequests/$medicationRequestId$

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