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Minimap2-2.8 (r672)

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@lh3 lh3 released this 01 Feb 17:53
· 510 commits to master since this release

Notable changes in this release include:

  • Speed up short-read alignment by ~10%. The overall mapping accuracy stays
    the same, but the output alignments are not always identical to v2.7 due to
    unstable sorting employed during chaining. Long-read alignment is not
    affected by this change as the speedup is short-read specific.

  • Mappy now supports paired-end short-read alignment (#87). Please see
    python/README.rst for details.

  • Added option --for-only and --rev-only to perform alignment against the
    forward or the reverse strand of the reference genome only (#91).

  • Alleviated the issue with undesired diagonal alignment in the self mapping
    mode (#10). Even if the output is not ideal, it should not interfere with
    other alignments. Fully resolving the issue is intricate and may require
    additional heuristic thresholds.

  • Enhanced error checking against incorrect input (#92 and #96).

For long query sequences, minimap2 should output identical alignments to v2.7.

(2.8: 1 February 2018, r672)