new content from pmc

figures/PMC11259605__LSA-2024-02586_FigS1.yml

@@ -1,3 +1,4 @@
+---
 pmcid: PMC11259605
 image_filename: LSA-2024-02586_FigS1.jpg
 figure_link: /pmc/articles/PMC11259605/figure/figS1/
@@ -15,11 +16,11 @@ caption: (A) Analysis of genes up-regulated in Lo-CBX5 patients when compared to
 article_title: Defective Integrator activity shapes the transcriptome of patients
   with multiple sclerosis.
 citation: Yevheniia Porozhan, et al. Life Sci Alliance. 2024 Oct;7(10):e202402586.
+
 doi: 10.26508/lsa.202402586
 journal_title: Life Science Alliance
 journal_nlm_ta: Life Sci Alliance
 publisher_name: Life Science Alliance LLC
-keywords: ~
-status: 'Defective Integrator activity shapes the transcriptome of patients with multiple
-  sclerosis. https://doi.org/10.26508/lsa.202402586 '
-media: PMC11259605__LSA-2024-02586_FigS1.jpg
+
+keywords:
+---

figures/PMC11335993__11357_2024_1169_Fig1_HTML.yml

@@ -1,3 +1,4 @@
+---
 pmcid: PMC11335993
 image_filename: 11357_2024_1169_Fig1_HTML.jpg
 figure_link: /pmc/articles/PMC11335993/figure/Fig1/
@@ -18,14 +19,15 @@ caption: 'Aβ drives proteome-wide protein insolubility that resembles normal ag
   core insoluble proteome, Benjamini Hochberg FDR < 5%'
 article_title: Amyloid β accelerates age-related proteome-wide protein insolubility.
 citation: Edward Anderton, et al. GeroScience. 2024 Oct;46(5):4585-4602.
+
 doi: 10.1007/s11357-024-01169-1
 journal_title: GeroScience
 journal_nlm_ta: GeroScience
 publisher_name: Springer International Publishing
+
 keywords:
 - Amyloid β
 - Proteostasis
 - Protein insolubility
-status: 'Amyloid β accelerates age-related proteome-wide protein insolubility. https://doi.org/10.1007/s11357-024-01169-1
-  #AmyloidΒ #Proteostasis #ProteinInsolubility'
-media: PMC11335993__11357_2024_1169_Fig1_HTML.jpg
+
+---

figures/PMC11519399__41598_2024_76401_Fig1_HTML.yml

@@ -0,0 +1,36 @@
+---
+pmcid: PMC11519399
+image_filename: 41598_2024_76401_Fig1_HTML.jpg
+figure_link: /pmc/articles/PMC11519399/figure/Fig1/
+number: Fig. 1
+figure_title: ''
+caption: Description of work flow for analysis of blood RNA transcriptional profiles
+  in COVID-19 cases. Samples were categorized based on COVID-19 cases with Symptomatic
+  or Asymptomatic infections. They were identified by their infecting SARS-CoV-2 variant
+  as wildtype, or Variants of Concern (VOC). Whole blood was processed for RNA microarray
+  analysis using the Affymetrix system and differentially regulated genes identified
+  (DEGs) identified. These were analysed by bioinformatics analysis using KEGG GO,
+  Reactome and WikiPathways.
+article_title: SARS-CoV-2 variants induce increased inflammatory gene expression but
+  reduced interferon responses and heme synthesis as compared with wild type strains.
+citation: Mariam Merchant, et al. Sci Rep. 2024;14:25734.
+
+doi: 10.1038/s41598-024-76401-1
+journal_title: Scientific Reports
+journal_nlm_ta: Sci Rep
+publisher_name: Nature Publishing Group UK
+
+keywords:
+- SARS-CoV-2
+- Variants of concern
+- EGR1
+- ALAS2
+- ISG
+- Delta variant
+- Infectious diseases
+- Pathogenesis
+- Computational biology and bioinformatics
+- Gene ontology
+- Genome informatics
+
+---

figures/PMC11519399__41598_2024_76401_Fig7_HTML.yml

@@ -0,0 +1,41 @@
+---
+pmcid: PMC11519399
+image_filename: 41598_2024_76401_Fig7_HTML.jpg
+figure_link: /pmc/articles/PMC11519399/figure/Fig7/
+number: Fig. 7
+figure_title: ''
+caption: Differential transcriptional expression between Asymptomatic cases infected
+  with VOC or wildtype SARS-CoV-2. (A) Principal component analysis helps to visualize
+  the clustering of COVID-19 Asymptomatic cases infected with wildtype, or VOC (n = 5)
+  strains. (B) A barplot depicts the hierarchical clustering of differentially expressed
+  genes (DEGs) as Upregulated (red) or Downregulated (green) between individuals infected
+  with VOC as compared with VOC. (C) A volcano plot of DEGs between infection with
+  VOC or wt infections. The x-axis is labelled by fold change and y-axis shows –log10(p-value),
+  the red dot depicts up-regulated genes and blue represents downregulated genes.
+  (D) GSE of Biological processes run on the DEGs. (E) GSE WikiPathways analysis is
+  depicted. Pathways details are displayed on the y-axis and gene ratio is plotted
+  on x-axis. The greater the size of circle the greater the number of genes involved
+  in a pathway; the circles are colored based on p-adjusted value.
+article_title: SARS-CoV-2 variants induce increased inflammatory gene expression but
+  reduced interferon responses and heme synthesis as compared with wild type strains.
+citation: Mariam Merchant, et al. Sci Rep. 2024;14:25734.
+
+doi: 10.1038/s41598-024-76401-1
+journal_title: Scientific Reports
+journal_nlm_ta: Sci Rep
+publisher_name: Nature Publishing Group UK
+
+keywords:
+- SARS-CoV-2
+- Variants of concern
+- EGR1
+- ALAS2
+- ISG
+- Delta variant
+- Infectious diseases
+- Pathogenesis
+- Computational biology and bioinformatics
+- Gene ontology
+- Genome informatics
+
+---

figures/fetch.log

@@ -1,2 +1,2 @@
-https://www.ncbi.nlm.nih.gov/pmc/?term=((wikipathways+OR+pathvisio))+AND+(2024/09/01[PUBDATE]+%3A+3000/01/01[PUBDATE])&report=imagesdocsum&dispmax=100
+https://www.ncbi.nlm.nih.gov/pmc/?term=((wikipathways+OR+pathvisio))+AND+(2024/10/01[PUBDATE]+%3A+3000/01/01[PUBDATE])&report=imagesdocsum&dispmax=100
  4 results

query_config.yml

@@ -1,3 +1,3 @@
 terms: (wikipathways+OR+pathvisio)
-last_run: 2024/10/01
+last_run: 2024/11/01
 date_range: ~