Update tsv, md and png files

_data/WP4814-bibliography.tsv

@@ -1,2 +1,3 @@
 ID	Database	Citation
+27378692	Pubmed	"A recurrent p.Arg92Trp variant in steroidogenic factor-1 (NR5A1) can act as a molecular switch in human sex development. Bashamboo A, Donohoue PA, Vilain E, Rojo S, Calvel P, Seneviratne SN, et al. Hum Mol Genet. 2016 Aug 15;25(16):3446–53.  <a href=""http://www.ncbi.nlm.nih.gov/pubmed/27378692"" target=""_blank"" class=""external"" rel=""nofollow"">PubMed</a> <a href=""https://europepmc.org/abstract/MED/27378692"" target=""_blank"" class=""external"" rel=""nofollow"">Europe PMC</a> <a href=""https://scholia.toolforge.org/pubmed/27378692"" target=""_blank"" class=""external"" rel=""nofollow"">Scholia</a>"
 27915330	Pubmed	"Mechanism of Sex Determination in Humans: Insights from Disorders of Sex Development. Bashamboo A, McElreavey K. Sex Dev. 2016;10(5–6):313–25.  <a href=""http://www.ncbi.nlm.nih.gov/pubmed/27915330"" target=""_blank"" class=""external"" rel=""nofollow"">PubMed</a> <a href=""https://europepmc.org/abstract/MED/27915330"" target=""_blank"" class=""external"" rel=""nofollow"">Europe PMC</a> <a href=""https://scholia.toolforge.org/pubmed/27915330"" target=""_blank"" class=""external"" rel=""nofollow"">Scholia</a>"

_data/WP4814-datanodes.tsv

@@ -1,5 +1,7 @@
 Label	Type	Identifier	Comment	Ensembl	NCBI gene	HGNC	UniProt	Wikidata	ChEBI	InChI	PubChem	ChemSpider	HMDB	KEGG	LipidMaps
+ZFPM2	GeneProduct	ncbigene:23414	""	ensembl:ENSG00000169946	ncbigene:23414	hgnc.symbol:ZFPM2	uniprot:Q8WW38;uniprot:E7ET52;uniprot:E5RJX0								
 DHH	GeneProduct	ensembl:ENSG00000139549	""	ensembl:ENSG00000139549	ncbigene:50846	hgnc.symbol:DHH	uniprot:O43323								
+CTNNB1	GeneProduct	ncbigene:1499	""	ensembl:ENSG00000168036	ncbigene:1499	hgnc.symbol:CTNNB1	uniprot:A0A2R8Y6G0;uniprot:A0A2R8Y804;uniprot:A0A2R8Y815;uniprot:A0A2R8Y5A3;uniprot:C9IZ65;uniprot:A0A2R8Y5C3;uniprot:P35222;uniprot:A0A2R8Y7Z0;uniprot:A0A2R8YG06;uniprot:A0A2R8Y5Z1;uniprot:A0A2R8Y750;uniprot:A0A2R8YCH5;uniprot:A0A024R2Q3;uniprot:A0A2R8Y543;uniprot:B4DGU4								
 FOXL2	GeneProduct	ensembl:ENSG00000183770	""	ensembl:ENSG00000183770	ncbigene:668	hgnc.symbol:FOXL2	uniprot:P58012;uniprot:Q53ZD3								
 SOX9	GeneProduct	ensembl:ENSG00000125398	""	ensembl:ENSG00000125398	ncbigene:6662	hgnc.symbol:SOX9	uniprot:P48436								
 AMH	GeneProduct	ensembl:ENSG00000104899	""	ensembl:ENSG00000104899	ncbigene:268	hgnc.symbol:AMH	uniprot:P03971								

_data/WP5504-bibliography.tsv

@@ -1,4 +1,6 @@
 ID	Database	Citation
 9783642403361	ISBN	"Physician’s Guide to the Diagnosis, Treatment, and Follow-Up of Inherited Metabolic Diseases [Internet]. Blau N, Duran M, Gibson KM, Dionisi-Vici C. Springer; 2014. 0 p. Available from: https://books.google.com/books/about/Physician_s_Guide_to_the_Diagnosis_Treat.html?hl=&id=wJRBnwEACAAJ <a href=""https://openlibrary.org/search?isbn=9783642403361"" target=""_blank"" class=""external"" rel=""nofollow"">OpenLibrary</a> <a href=""https://www.worldcat.org/search?qt=wikipathways&q=isbn%3A9783642403361"" target=""_blank"" class=""external"" rel=""nofollow"">Worldcat</a>"
 37884807	Pubmed	"Mitochondrial matrix RTN4IP1/OPA10 is an oxidoreductase for coenzyme Q synthesis. Park I, Kim KE, Kim J, Kim AK, Bae S, Jung M, et al. Nat Chem Biol. 2024 Feb;20(2):221–33.  <a href=""http://www.ncbi.nlm.nih.gov/pubmed/37884807"" target=""_blank"" class=""external"" rel=""nofollow"">PubMed</a> <a href=""https://europepmc.org/abstract/MED/37884807"" target=""_blank"" class=""external"" rel=""nofollow"">Europe PMC</a> <a href=""https://scholia.toolforge.org/pubmed/37884807"" target=""_blank"" class=""external"" rel=""nofollow"">Scholia</a>"
+38199007	Pubmed	"Identification of TMEM126A as OXA1L-interacting protein reveals cotranslational quality control in mitochondria. Poerschke S, Oeljeklaus S, Cruz-Zaragoza LD, Schenzielorz A, Dahal D, Hillen HS, et al. Mol Cell. 2024 Jan 18;84(2):345-358.e5.  <a href=""http://www.ncbi.nlm.nih.gov/pubmed/38199007"" target=""_blank"" class=""external"" rel=""nofollow"">PubMed</a> <a href=""https://europepmc.org/abstract/MED/38199007"" target=""_blank"" class=""external"" rel=""nofollow"">Europe PMC</a> <a href=""https://scholia.toolforge.org/pubmed/38199007"" target=""_blank"" class=""external"" rel=""nofollow"">Scholia</a>"
+38891822	Pubmed	"Valosin-Containing Protein (VCP): A Review of Its Diverse Molecular Functions and Clinical Phenotypes. Pontifex CS, Zaman M, Fanganiello RD, Shutt TE, Pfeffer G. Int J Mol Sci. 2024 May 22;25(11):5633.  <a href=""http://www.ncbi.nlm.nih.gov/pubmed/38891822"" target=""_blank"" class=""external"" rel=""nofollow"">PubMed</a> <a href=""https://europepmc.org/abstract/MED/38891822"" target=""_blank"" class=""external"" rel=""nofollow"">Europe PMC</a> <a href=""https://scholia.toolforge.org/pubmed/38891822"" target=""_blank"" class=""external"" rel=""nofollow"">Scholia</a>"
 39075050	Pubmed	"Deubiquitinase USP9x regulates the proline biosynthesis pathway in non-small cell lung cancer. Becirovic T, Zhang B, Lindskog C, Norberg E, Vakifahmetoglu-Norberg H, Kaminskyy VO, et al. Cell Death Discov. 2024 Jul 29;10(1):342.  <a href=""http://www.ncbi.nlm.nih.gov/pubmed/39075050"" target=""_blank"" class=""external"" rel=""nofollow"">PubMed</a> <a href=""https://europepmc.org/abstract/MED/39075050"" target=""_blank"" class=""external"" rel=""nofollow"">Europe PMC</a> <a href=""https://scholia.toolforge.org/pubmed/39075050"" target=""_blank"" class=""external"" rel=""nofollow"">Scholia</a>"

_data/WP5504-datanodes.tsv

@@ -1,8 +1,10 @@
 Label	Type	Identifier	Comment	Ensembl	NCBI gene	HGNC	UniProt	Wikidata	ChEBI	InChI	PubChem	ChemSpider	HMDB	KEGG	LipidMaps
+arginine	Metabolite	chebi:29016	""					wikidata:Q27104032	chebi:29016	inchikey:ODKSFYDXXFIFQN-UHFFFAOYSA-N	pubchem.compound:59119146;pubchem.compound:232;pubchem.compound:5246487	chemspider:227	hmdb:HMDB0251511	kegg.compound:C02385	
 NADPH	Metabolite	chebi:16474	"cofactor to PYCR3"					wikidata:Q26841327	chebi:16474	inchikey:ACFIXJIJDZMPPO-NNYOXOHSSA-N	pubchem.compound:5884	chemspider:5673	hmdb:HMDB0000221	kegg.compound:C00005	
 pyrroline-5-carboxylate	Metabolite	chebi:15893	"AKA P5C"					wikidata:Q27098284	chebi:15893	inchikey:DWAKNKKXGALPNW-UHFFFAOYSA-M	pubchem.compound:11966213	chemspider:10140206		kegg.compound:C04322	
 Proline	Metabolite	chebi:26271	""					wikidata:Q484583	chebi:26271	inchikey:ONIBWKKTOPOVIA-UHFFFAOYSA-N	pubchem.compound:25246272;pubchem.compound:614	chemspider:594	hmdb:HMDB0251528	kegg.compound:C16435	
 biotin	Metabolite	chebi:15956	""					wikidata:Q181354	chebi:15956	inchikey:YBJHBAHKTGYVGT-ZKWXMUAHSA-N	pubchem.compound:171548	chemspider:149962	hmdb:HMDB0000030	kegg.compound:C00120	
+ornithine	Metabolite	chebi:18257	""					wikidata:Q27102952	chebi:18257	inchikey:AHLPHDHHMVZTML-UHFFFAOYSA-N	pubchem.compound:134895646;pubchem.compound:389	chemspider:380		kegg.compound:C01602	lipidmaps:LMFA01100057
 glutamate	Metabolite	chebi:14321	""					wikidata:Q27108980	chebi:14321	inchikey:WHUUTDBJXJRKMK-UHFFFAOYSA-M	pubchem.compound:4452358;pubchem.compound:4179667;pubchem.compound:4525487	chemspider:3390755			
 α-Ketoglutarate	Metabolite	chebi:30915	"aka 2-oxoglutaric acid"					wikidata:Q306140	chebi:30915	inchikey:KPGXRSRHYNQIFN-UHFFFAOYSA-N	pubchem.compound:156274072;pubchem.compound:51	chemspider:50	hmdb:HMDB0000208	kegg.compound:C00026	
 AFG3L2	GeneProduct	ensembl:ENSG00000141385	""	ensembl:ENSG00000141385	ncbigene:10939	hgnc.symbol:AFG3L2	uniprot:K7EP56;uniprot:Q9Y4W6								
@@ -16,6 +18,7 @@ GFER	GeneProduct	hgnc.symbol:GFER	""	ensembl:ENSG00000127554	ncbigene:2671	hgnc.
 HSPA9	GeneProduct	ensembl:ENSG00000113013	""	ensembl:ENSG00000113013	ncbigene:3313	hgnc.symbol:HSPA9	uniprot:A0A7I2V3F7;uniprot:A0A7I2V3D9;uniprot:H0Y8K0;uniprot:A0A384P5G6;uniprot:A0A7I2V4A9;uniprot:D6RCD7;uniprot:A0A3B3ITI4;uniprot:A0A7I2YQQ5;uniprot:A0A7I2V2S7;uniprot:A0A7I2V2G2;uniprot:A0A7I2V2K6;uniprot:P38646;uniprot:H0Y8S0;uniprot:A0A7I2YQB2								
 HSPD1	GeneProduct	ensembl:ENSG00000144381	""	ensembl:ENSG00000144381	ncbigene:3329	hgnc.symbol:HSPD1	uniprot:C9JL19;uniprot:E7ESH4;uniprot:A0A7I2YQ71;uniprot:C9JL25;uniprot:F8WBB1;uniprot:C9J0S9;uniprot:A0A7I2V2X6;uniprot:P10809;uniprot:E7EXB4;uniprot:A0A024R3X4;uniprot:A0A7I2V369;uniprot:A0A7I2V599;uniprot:A0A7I2V5M1;uniprot:A0A7I2YQK6;uniprot:C9JCQ4;uniprot:A0A7I2V5K3								
 HTRA2	GeneProduct	ensembl:ENSG00000115317	""	ensembl:ENSG00000115317	ncbigene:27429	hgnc.symbol:HTRA2	uniprot:A0A384MDW9;uniprot:A0A0C4DG44;uniprot:O43464								
+LONP1	GeneProduct	uniprot:P36776	""	ensembl:ENSG00000196365	ncbigene:9361	hgnc.symbol:LONP1	uniprot:K7ERS1;uniprot:K7EJE8;uniprot:K7EKE6;uniprot:K7ERR6;uniprot:K7ER27;uniprot:P36776;uniprot:K7EQF8;uniprot:K7ER56								
 MIPEP	GeneProduct	ensembl:ENSG00000027001	""	ensembl:ENSG00000027001	ncbigene:4285	hgnc.symbol:MIPEP	uniprot:Q99797								
 PAM16	GeneProduct	ensembl:ENSG00000217930	""	ensembl:ENSG00000217930	ncbigene:51025	hgnc.symbol:PAM16	uniprot:Q9Y3D7;uniprot:A0A0B4J298;uniprot:I3L1U7;uniprot:I3L3G8;uniprot:I3L0X9;uniprot:I3L1K9;uniprot:I3L3T0								
 PITRM1	GeneProduct	ensembl:ENSG00000107959	""	ensembl:ENSG00000107959	ncbigene:10531	hgnc.symbol:PITRM1	uniprot:A0A7I2V5C6;uniprot:A0A7I2V3B6;uniprot:A0A7I2YQX5;uniprot:A0A7I2YQT2;uniprot:A0A7I2V3X0;uniprot:A0A7I2V2T0;uniprot:H0Y7L7;uniprot:H0Y4F7;uniprot:A0A7I2V397;uniprot:B4DEU0;uniprot:A0A7I2V4X7;uniprot:A0A0A0MRX9;uniprot:A0A7I2V5R2;uniprot:B1APQ0;uniprot:A0A7I2V449;uniprot:A0A7I2V4N3;uniprot:B1APQ1;uniprot:A0A7I2V5K2;uniprot:A0A7I2V3L7;uniprot:A0A7I2V5H2;uniprot:Q5JRX3								
@@ -44,9 +47,12 @@ TXNRD2	GeneProduct	ensembl:ENSG00000184470	""	ensembl:ENSG00000184470	ncbigene:1
 MICU1	GeneProduct	ensembl:ENSG00000107745	""	ensembl:ENSG00000107745	ncbigene:10367	hgnc.symbol:MICU1	uniprot:S4R3V1;uniprot:S4R3W3;uniprot:A0A0U1RRK1;uniprot:A0A286YF11;uniprot:S4R3D7;uniprot:E9PQV6;uniprot:Q9BPX6								
 ATAD3A	GeneProduct	ensembl:ENSG00000197785	""	ensembl:ENSG00000197785	ncbigene:55210	hgnc.symbol:ATAD3A	uniprot:H0Y2W2;uniprot:Q5SV16;uniprot:Q9NVI7								
 MICOS13	GeneProduct	ensembl:ENSG00000174917	""	ensembl:ENSG00000174917	ncbigene:125988	hgnc.symbol:MICOS13	uniprot:A0A140TA84;uniprot:A0A140TA86;uniprot:Q5XKP0;uniprot:K7EIR2								
+UBXN1	Protein	uniprot:Q04323	""	ensembl:ENSG00000162191	ncbigene:51035	hgnc.symbol:UBXN1	uniprot:A0A024R539;uniprot:E9PRQ7;uniprot:E9PS08;uniprot:A0A087WTZ5;uniprot:Q04323;uniprot:A0A024R598;uniprot:E9PJ81								
+OXA1L	Protein	uniprot:Q15070	""	ensembl:ENSG00000155463	ncbigene:5018	hgnc.symbol:OXA1L	uniprot:E7EVY0;uniprot:H7BZE6;uniprot:J3KNA0;uniprot:Q15070;uniprot:C9JC63;uniprot:A0A087X0L7								
 YME1L1	Protein	uniprot:Q96TA2	"Not in Figure, but added in Table 46.35"	ensembl:ENSG00000136758	ncbigene:10730	hgnc.symbol:YME1L1	uniprot:R4GNA5;uniprot:Q6PJ89;uniprot:Q5T8D2;uniprot:Q5T8D1;uniprot:Q96TA2								
 PYCR3	Protein	uniprot:Q53H96	"Active in Cytosol"	ensembl:ENSG00000104524	ncbigene:65263	hgnc.symbol:PYCR3	uniprot:A0A087WTU2;uniprot:F8WEI0;uniprot:A0A0A0MQS1;uniprot:B5MD87;uniprot:Q53H96								
 OPA3?	Protein	uniprot:Q9H6K4	""	ensembl:ENSG00000125741	ncbigene:80207	hgnc.symbol:OPA3	uniprot:B4DK77;uniprot:Q9H6K4								
+UFD1	Protein	uniprot:Q92890	""	ensembl:ENSG00000070010	ncbigene:7353	hgnc.symbol:UFD1	uniprot:C9J6N9;uniprot:Q92890;uniprot:C9J7C8;uniprot:Q541A5;uniprot:C9IZG3;uniprot:C9JNP9								
 COQ3	Protein	uniprot:Q9NZJ6	""	ensembl:ENSG00000132423	ncbigene:51805	hgnc.symbol:COQ3	uniprot:F6WGP0;uniprot:Q9NZJ6								
 MSTO1?	Protein	uniprot:Q9BUK6	""	ensembl:ENSG00000125459	ncbigene:55154	hgnc.symbol:MSTO1	uniprot:V9GYF2;uniprot:Q9BUK6;uniprot:A0A3B3IUD2								
 SACS?	Protein	uniprot:Q9NZJ4	""	ensembl:ENSG00000151835	ncbigene:26278	hgnc.symbol:SACS	uniprot:A0A804HHS6;uniprot:A0A804HL98;uniprot:A0A804HK57;uniprot:H0Y6M8;uniprot:A0A804HKY6;uniprot:A0A804HIQ1;uniprot:A0A804HJS2;uniprot:B2REB0;uniprot:A0A804HLL1;uniprot:Q9NZJ4;uniprot:A0A804HK18;uniprot:A0A804HKB3;uniprot:A0A804HIG5;uniprot:A0A804HLK7;uniprot:A0A804HIU0								
@@ -59,3 +65,10 @@ PYCR1	Protein	uniprot:P32322	"Active in Cytosol"	ensembl:ENSG00000183010	ncbigen
 PYCR2	Protein	uniprot:Q96C36	"Active in Cytosol"	ensembl:ENSG00000143811	ncbigene:29920	hgnc.symbol:PYCR2	uniprot:A0A087WX69;uniprot:A0A0S2Z5U6;uniprot:A0A087WTV6;uniprot:A0A087WZF0;uniprot:Q96C36								
 OPA3	Protein	uniprot:Q9H6K4	""	ensembl:ENSG00000125741	ncbigene:80207	hgnc.symbol:OPA3	uniprot:B4DK77;uniprot:Q9H6K4								
 MSTO1	Protein	uniprot:Q9BUK6	""	ensembl:ENSG00000125459	ncbigene:55154	hgnc.symbol:MSTO1	uniprot:V9GYF2;uniprot:Q9BUK6;uniprot:A0A3B3IUD2								
+LONP1	Protein	uniprot:P36776	""	ensembl:ENSG00000196365	ncbigene:9361	hgnc.symbol:LONP1	uniprot:K7ERS1;uniprot:K7EJE8;uniprot:K7EKE6;uniprot:K7ERR6;uniprot:K7ER27;uniprot:P36776;uniprot:K7EQF8;uniprot:K7ER56								
+NPLOC4	Protein	uniprot:Q8TAT6	"AKA NPL4"	ensembl:ENSG00000182446	ncbigene:55666	hgnc.symbol:NPLOC4	uniprot:Q8TAT6;uniprot:A0A0D9SFI9;uniprot:I3L4U9;uniprot:I3L4S2;uniprot:K7EJN1;uniprot:I3L283;uniprot:I3L281;uniprot:I3L3I1;uniprot:A0A024R8R4;uniprot:I3L0W3								
+p47	Protein	uniprot:P08567	""	ensembl:ENSG00000115956	ncbigene:5341	hgnc.symbol:PLEK	uniprot:P08567								
+MFN1	Protein	uniprot:Q8IWA4	""	ensembl:ENSG00000171109	ncbigene:55669	hgnc.symbol:MFN1	uniprot:C9JQT7;uniprot:Q8IWA4;uniprot:H7C5H5;uniprot:C9JXQ1								
+UBXD1/UBXN6	Protein	uniprot:Q9BZV1	""	ensembl:ENSG00000167671	ncbigene:80700	hgnc.symbol:UBXN6	uniprot:K7ELN1;uniprot:K7EP32;uniprot:Q9BZV1;uniprot:K7EJ02								
+MCL1	Protein	uniprot:Q07820	""	ensembl:ENSG00000143384	ncbigene:574406;ncbigene:4170	hgnc.symbol:MCL1	uniprot:Q07820;uniprot:A0A087WT64;uniprot:A0A7I2V2W2								
+MARCHF5	Protein	uniprot:Q9NX47	"MITOL/March5"	ensembl:ENSG00000198060	ncbigene:54708	hgnc.symbol:MARCHF5	uniprot:Q9NX47								

_pathways/WP3611.md

@@ -23,19 +23,20 @@ citedin:
   title: 'A Practical Strategy for Exploring the Pharmacological Mechanism of Luteolin
     Against COVID-19/Asthma Comorbidity: Findings of System Pharmacology and Bioinformatics
     Analysis (2024)'
+communities: []
 description: Photodynamic therapy may induce an acute stress response mediated by
   mitogen-activated protein kinase kinase kinase 5 (MAP3K5), its downstream MAPKs
   that target c-Jun N-terminal kinase (JNK, MAPK8) and p38MAPK, and the transcription
   factors of the activator protein 1 (AP-1) family.
-last-edited: 2021-12-09
+last-edited: 2024-12-20
 ndex: 274026a0-8b67-11eb-9e72-0ac135e8bacf
 organisms:
 - Homo sapiens
 redirect_from:
 - /index.php/Pathway:WP3611
 - /instance/WP3611
-- /instance/WP3611_r120501
-revision: r120501
+- /instance/WP3611_r136148
+revision: r136148
 schema-jsonld:
 - '@context': https://schema.org/
   '@id': https://wikipathways.github.io/pathways/WP3611.html

_pathways/WP4030.md

@@ -30,15 +30,15 @@ description: 'The short-chain fatty acids (SCFA) acetate, propionate and butyrat
   transporter type 4 (GLUT4) and decreases glycolysis. In addition to AMPK activation,
   SCFA might also induce peroxisome proliferator activated receptor delta (PPARD)
   expression, another process contributing to enhanced fat oxidation levels.    '
-last-edited: 2024-12-19
+last-edited: 2024-12-20
 ndex: 331ac03a-8b69-11eb-9e72-0ac135e8bacf
 organisms:
 - Homo sapiens
 redirect_from:
 - /index.php/Pathway:WP4030
 - /instance/WP4030
-- /instance/WP4030_r136104
-revision: r136104
+- /instance/WP4030_r136145
+revision: r136145
 schema-jsonld:
 - '@context': https://schema.org/
   '@id': https://wikipathways.github.io/pathways/WP4030.html

_pathways/WP4814.md

@@ -1,54 +1,60 @@
 ---
 annotations:
+- id: CL:0000178
+  parent: native cell
+  type: Cell Type Ontology
+  value: Leydig cell
+- id: DOID:1923
+  type: Disease Ontology
+  value: disorder of sexual development
 - id: PW:0000003
   parent: signaling pathway
   type: Pathway Ontology
   value: signaling pathway
-- id: DOID:1923
-  type: Disease Ontology
-  value: disorder of sexual development
 authors:
 - JenG
 - Fehrhart
 - Eweitz
+- Khanspers
 citedin:
 - link: 10.1186/s13148-023-01612-8
   title: 'Methylation analysis by targeted bisulfite sequencing in large for gestational
     age (LGA) newborns: the LARGAN cohort (2024)'
 communities:
 - RareDiseases
-description: This pathway describes the sex determination in a fetus.  For the male
+description: 'This pathway describes the sex determination in a fetus.  For the male
   development the SRY gene plays an important role, leading to the SOX9 expression
   which will then stimulate AMH expression and testis development. In adults DMRT1
   and SOX9 inhibit the FOXL2 gene, maintaining the male sex determination.  For the
   female development the WNT4 and RSPO1 signaling pathways lead to beta-catenin accumulation
   which inhibits SOX9 and the development of ovaries. In adults, Foxl2 repress Sox9
-  expression to maintain ovarian identity.
-last-edited: 2021-05-07
+  expression to maintain ovarian identity. '
+last-edited: 2024-12-20
 ndex: b6c7699b-8b6d-11eb-9e72-0ac135e8bacf
 organisms:
 - Homo sapiens
 redirect_from:
 - /index.php/Pathway:WP4814
 - /instance/WP4814
-- /instance/WP4814_r116554
-revision: r116554
+- /instance/WP4814_r136147
+revision: r136147
 schema-jsonld:
 - '@context': https://schema.org/
   '@id': https://wikipathways.github.io/pathways/WP4814.html
   '@type': Dataset
   creator:
     '@type': Organization
     name: WikiPathways
-  description: This pathway describes the sex determination in a fetus.  For the male
-    development the SRY gene plays an important role, leading to the SOX9 expression
+  description: 'This pathway describes the sex determination in a fetus.  For the
+    male development the SRY gene plays an important role, leading to the SOX9 expression
     which will then stimulate AMH expression and testis development. In adults DMRT1
     and SOX9 inhibit the FOXL2 gene, maintaining the male sex determination.  For
     the female development the WNT4 and RSPO1 signaling pathways lead to beta-catenin
     accumulation which inhibits SOX9 and the development of ovaries. In adults, Foxl2
-    repress Sox9 expression to maintain ovarian identity.
+    repress Sox9 expression to maintain ovarian identity. '
   keywords:
   - AMH
+  - CTNNB1
   - DHH
   - DMRT1
   - FGF9
@@ -62,6 +68,7 @@ schema-jsonld:
   - SRY
   - WNT4
   - WT1
+  - ZFPM2
   license: CC0
   name: Somatic sex determination
 seo: CreativeWork

_pathways/WP5504.md

@@ -1,13 +1,13 @@
 ---
 annotations:
-- id: PW:0000013
-  parent: disease pathway
-  type: Pathway Ontology
-  value: disease pathway
 - id: PW:0001669
   parent: disease pathway
   type: Pathway Ontology
   value: mitochondrial disease pathway
+- id: PW:0000013
+  parent: disease pathway
+  type: Pathway Ontology
+  value: disease pathway
 authors:
 - Egonw
 - DeSl
@@ -20,15 +20,15 @@ description: This pathway lists several genes involved in mechanisms involved in
   pathway was inspired by Figure 46.1 of Edition 5, Chapter 46 of the book of Blau
   (ISBN 9783030677268). Genes linked to a disease in this book chapter are depicted
   in red.
-last-edited: 2024-12-19
+last-edited: 2024-12-20
 ndex: null
 organisms:
 - Homo sapiens
 redirect_from:
 - /index.php/Pathway:WP5504
 - /instance/WP5504
-- /instance/WP5504_r136128
-revision: r136128
+- /instance/WP5504_r136141
+revision: r136141
 schema-jsonld:
 - '@context': https://schema.org/
   '@id': https://wikipathways.github.io/pathways/WP5504.html
@@ -58,17 +58,23 @@ schema-jsonld:
   - HSPA9
   - HSPD1
   - HTRA2
+  - LONP1
+  - MARCHF5
+  - MCL1
   - MFF
+  - MFN1
   - MFN2
   - MICOS13
   - MICU1
   - MIPEP
   - MSTO1
   - MSTO1?
   - NADPH
+  - NPLOC4
   - OPA1
   - OPA3
   - OPA3?
+  - OXA1L
   - PAM16
   - PINK1
   - PITRM1
@@ -93,12 +99,18 @@ schema-jsonld:
   - TRAK1
   - TXN2
   - TXNRD2
+  - UBXD1/UBXN6
+  - UBXN1
+  - UFD1
   - USP9X
   - VCP
   - 'XPNPEP3 '
   - YME1L1
+  - arginine
   - biotin
   - glutamate
+  - ornithine
+  - p47
   - pyrroline-5-carboxylate
   - α-Ketoglutarate
   license: CC0

_pathways/WP5505.md

@@ -1,21 +1,21 @@
 ---
 annotations:
-- id: PW:0000002
-  parent: classic metabolic pathway
-  type: Pathway Ontology
-  value: classic metabolic pathway
 - id: PW:0000161
   parent: classic metabolic pathway
   type: Pathway Ontology
   value: glycosylphosphatidylinositol anchor biosynthetic pathway
+- id: PW:0000002
+  parent: classic metabolic pathway
+  type: Pathway Ontology
+  value: classic metabolic pathway
 authors:
 - Egonw
 - Mkutmon
 citedin: ''
 communities:
 - MetaKids
 description: Literature reference
-last-edited: 2024-12-19
+last-edited: 2024-12-20
 ndex: null
 organisms:
 - Homo sapiens